Liin SI - Search Results

1

Mechanistic insights into robust cardiac I_Ks potassium channel activation by aromatic polyunsaturated fatty acid analogues.

Bohannon BM, Jowais JJ, Nyberg L, Olivier-Meo V, Corradi V, Tieleman DP, Liin SI, Larsson HP. Bohannon BM, et al. Among authors: liin si. Elife. 2023 Jun 23;12:e85773. doi: 10.7554/eLife.85773. Elife. 2023. PMID: 37350568 Free PMC article.

2

KCNE1 divides the voltage sensor movement in KCNQ1/KCNE1 channels into two steps.

Barro-Soria R, Rebolledo S, Liin SI, Perez ME, Sampson KJ, Kass RS, Larsson HP. Barro-Soria R, et al. Among authors: liin si. Nat Commun. 2014 Apr 28;5:3750. doi: 10.1038/ncomms4750. Nat Commun. 2014. PMID: 24769622 Free PMC article.

3

The KCNQ1 channel - remarkable flexibility in gating allows for functional versatility.

Liin SI, Barro-Soria R, Larsson HP. Liin SI, et al. J Physiol. 2015 Jun 15;593(12):2605-15. doi: 10.1113/jphysiol.2014.287607. Epub 2015 Mar 18. J Physiol. 2015. PMID: 25653179 Free PMC article. Review.

4

Polyunsaturated fatty acid analogs act antiarrhythmically on the cardiac IKs channel.

Liin SI, Silverå Ejneby M, Barro-Soria R, Skarsfeldt MA, Larsson JE, Starck Härlin F, Parkkari T, Bentzen BH, Schmitt N, Larsson HP, Elinder F. Liin SI, et al. Proc Natl Acad Sci U S A. 2015 May 5;112(18):5714-9. doi: 10.1073/pnas.1503488112. Epub 2015 Apr 21. Proc Natl Acad Sci U S A. 2015. PMID: 25901329 Free PMC article.

5

Fatty acid analogue N-arachidonoyl taurine restores function of I_Ks channels with diverse long QT mutations.

Liin SI, Larsson JE, Barro-Soria R, Bentzen BH, Larsson HP. Liin SI, et al. Elife. 2016 Sep 30;5:e20272. doi: 10.7554/eLife.20272. Elife. 2016. PMID: 27690226 Free PMC article.

6

Specificity of M-channel activators: binding or effect?

Barro-Soria R, Liin SI, Larsson HP. Barro-Soria R, et al. Among authors: liin si. J Physiol. 2017 Feb 1;595(3):605-606. doi: 10.1113/JP273250. J Physiol. 2017. PMID: 28145011 Free PMC article. No abstract available.

7

Using fluorescence to understand β subunit-Na_V channel interactions.

Barro-Soria R, Liin SI, Larsson HP. Barro-Soria R, et al. Among authors: liin si. J Gen Physiol. 2017 Jul 18;149(8):757-62. doi: 10.1085/jgp.201711843. Online ahead of print. J Gen Physiol. 2017. PMID: 28720591 Free PMC article.

8

KCNE1 and KCNE3 modulate KCNQ1 channels by affecting different gating transitions.

Barro-Soria R, Ramentol R, Liin SI, Perez ME, Kass RS, Larsson HP. Barro-Soria R, et al. Among authors: liin si. Proc Natl Acad Sci U S A. 2017 Aug 29;114(35):E7367-E7376. doi: 10.1073/pnas.1710335114. Epub 2017 Aug 14. Proc Natl Acad Sci U S A. 2017. PMID: 28808020 Free PMC article.

9

KCNE1 tunes the sensitivity of K_V7.1 to polyunsaturated fatty acids by moving turret residues close to the binding site.

Larsson JE, Larsson HP, Liin SI. Larsson JE, et al. Among authors: liin si. Elife. 2018 Jul 17;7:e37257. doi: 10.7554/eLife.37257. Elife. 2018. PMID: 30014849 Free PMC article.

10

ω-6 and ω-9 polyunsaturated fatty acids with double bonds near the carboxyl head have the highest affinity and largest effects on the cardiac I_K_s potassium channel.

Bohannon BM, Perez ME, Liin SI, Larsson HP. Bohannon BM, et al. Among authors: liin si. Acta Physiol (Oxf). 2019 Feb;225(2):e13186. doi: 10.1111/apha.13186. Epub 2018 Oct 17. Acta Physiol (Oxf). 2019. PMID: 30184322 Free PMC article.

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