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Page 1
Association of Statin Use With Risk of Liver Disease, Hepatocellular Carcinoma, and Liver-Related Mortality.
Vell MS, Loomba R, Krishnan A, Wangensteen KJ, Trebicka J, Creasy KT, Trautwein C, Scorletti E, Seeling KS, Hehl L, Rendel MD, Zandvakili I, Li T, Chen J, Vujkovic M, Alqahtani S, Rader DJ, Schneider KM, Schneider CV. Vell MS, et al. Among authors: scorletti e. JAMA Netw Open. 2023 Jun 1;6(6):e2320222. doi: 10.1001/jamanetworkopen.2023.20222. JAMA Netw Open. 2023. PMID: 37358849 Free PMC article.
A coding variant in the microsomal triglyceride transfer protein reduces both hepatic steatosis and plasma lipids.
Schneider CV, Hehl L, Creasy KT, Vitali C, Vell MS, Vujkovic M, Park J, Scorletti E, Seeling KS, Rendel MD, Conlon DM, Huang H, Zandvakili I, Valmiki S; Regeneron Center; Schneider KM, Hussain MM, Rader DJ. Schneider CV, et al. Among authors: scorletti e. Aliment Pharmacol Ther. 2023 Jul;58(2):238-249. doi: 10.1111/apt.17566. Epub 2023 May 29. Aliment Pharmacol Ther. 2023. PMID: 37248657
Large-scale identification of undiagnosed hepatic steatosis using natural language processing.
Schneider CV, Li T, Zhang D, Mezina AI, Rattan P, Huang H, Creasy KT, Scorletti E, Zandvakili I, Vujkovic M, Hehl L, Fiksel J, Park J, Wangensteen K, Risman M, Chang KM, Serper M, Carr RM, Schneider KM, Chen J, Rader DJ. Schneider CV, et al. Among authors: scorletti e. EClinicalMedicine. 2023 Aug 9;62:102149. doi: 10.1016/j.eclinm.2023.102149. eCollection 2023 Aug. EClinicalMedicine. 2023. PMID: 37599905 Free PMC article.
Aspirin is associated with a reduced incidence of liver disease in men.
Vell MS, Krishnan A, Wangensteen K, Serper M, Seeling KS, Hehl L, Rendel MD, Zandvakili I, Vujkovic M, Scorletti E, Creasy KT, Trautwein C, Rader DJ, Alqahtani S, Schneider KM, Schneider CV. Vell MS, et al. Among authors: scorletti e. Hepatol Commun. 2023 Sep 15;7(10):e0268. doi: 10.1097/HC9.0000000000000268. eCollection 2023 Oct 1. Hepatol Commun. 2023. PMID: 37708453 Free PMC article.
Ceramide synthase 6 (CerS6) is upregulated in alcohol-associated liver disease and exhibits sex-based differences in the regulation of energy homeostasis and lipid droplet accumulation.
Jeon S, Scorletti E, Dempsey J, Buyco D, Lin C, Saiman Y, Bayen S, Harkin J, Martin J, Hooks R, Ogretmen B, Argemi J, Melo L, Bataller R, Carr RM. Jeon S, et al. Among authors: scorletti e. Mol Metab. 2023 Dec;78:101804. doi: 10.1016/j.molmet.2023.101804. Epub 2023 Sep 14. Mol Metab. 2023. PMID: 37714377 Free PMC article.
Concomitant western diet and chronic-binge alcohol dysregulate hepatic metabolism.
Buyco DG, Dempsey JL, Scorletti E, Jeon S, Lin C, Harkin J, Bayen S, Furth EE, Martin J, Delima M, Hooks R, Sostre-Colón J, Gharib SA, Titchenell PM, Carr RM. Buyco DG, et al. Among authors: scorletti e. PLoS One. 2023 May 3;18(5):e0281954. doi: 10.1371/journal.pone.0281954. eCollection 2023. PLoS One. 2023. PMID: 37134024 Free PMC article.
The common p.Ile291Val variant of ERLIN1 enhances TM6SF2 function and is associated with protection against MASLD.
Rendel MD, Vitali C, Creasy KT, Zhang D, Scorletti E, Huang H, Seeling KS, Park J, Hehl L, Vell MS, Conlon D, Hayat S; Regeneron Center; Phillips MC, Schneider KM, Rader DJ, Schneider CV. Rendel MD, et al. Among authors: scorletti e. Med. 2024 Aug 9;5(8):963-980.e5. doi: 10.1016/j.medj.2024.04.010. Epub 2024 May 21. Med. 2024. PMID: 38776916 Free article.
A genome-first approach to variants in MLXIPL and their association with hepatic steatosis and plasma lipids.
Hehl L, Creasy KT, Vitali C, Scorletti E, Seeling KS, Vell MS, Rendel MD, Conlon D, Vujkovic M, Zandvakili I, Trautwein C, Schneider KM, Rader DJ, Schneider CV; Regeneron Genetics Center. Hehl L, et al. Among authors: scorletti e. Hepatol Commun. 2024 Apr 26;8(5):e0427. doi: 10.1097/HC9.0000000000000427. eCollection 2024 May 1. Hepatol Commun. 2024. PMID: 38668731 Free article.
65 results