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Page 1
Preclinical anti-tumour activity of HexaBody-CD38, a next-generation CD38 antibody with superior complement-dependent cytotoxic activity.
Hiemstra IH, Santegoets KCM, Janmaat ML, De Goeij BECG, Ten Hagen W, van Dooremalen S, Boross P, van den Brakel J, Bosgra S, Andringa G, van Kessel-Welmers B, Verzijl D, Hibbert RG, Frerichs KA, Mutis T, van de Donk NWCJ, Ahmadi T, Satijn D, Sasser AK, Breij ECW. Hiemstra IH, et al. Among authors: hibbert rg. EBioMedicine. 2023 Jul;93:104663. doi: 10.1016/j.ebiom.2023.104663. Epub 2023 Jun 26. EBioMedicine. 2023. PMID: 37379657 Free PMC article.
Comparison of methods generating antibody-epitope conjugates for targeting cancer with virus-specific T cells.
van der Wulp W, Gram AM, Bleijlevens B, Hagedoorn RS, Araman C, Kim RQ, Drijfhout JW, Parren PWHI, Hibbert RG, Hoeben RC, van Kasteren SI, Schuurman J, Ressing ME, Heemskerk MHM. van der Wulp W, et al. Among authors: hibbert rg. Front Immunol. 2023 May 16;14:1183914. doi: 10.3389/fimmu.2023.1183914. eCollection 2023. Front Immunol. 2023. PMID: 37261346 Free PMC article.
Dual Epitope Targeting and Enhanced Hexamerization by DR5 Antibodies as a Novel Approach to Induce Potent Antitumor Activity Through DR5 Agonism.
Overdijk MB, Strumane K, Beurskens FJ, Ortiz Buijsse A, Vermot-Desroches C, Vuillermoz BS, Kroes T, de Jong B, Hoevenaars N, Hibbert RG, Lingnau A, Forssmann U, Schuurman J, Parren PWHI, de Jong RN, Breij ECW. Overdijk MB, et al. Among authors: hibbert rg. Mol Cancer Ther. 2020 Oct;19(10):2126-2138. doi: 10.1158/1535-7163.MCT-20-0044. Epub 2020 Aug 26. Mol Cancer Ther. 2020. PMID: 32847982
Direct binding of Cdt2 to PCNA is important for targeting the CRL4Cdt2 E3 ligase activity to Cdt1.
Hayashi A, Giakoumakis NN, Heidebrecht T, Ishii T, Panagopoulos A, Caillat C, Takahara M, Hibbert RG, Suenaga N, Stadnik-Spiewak M, Takahashi T, Shiomi Y, Taraviras S, von Castelmur E, Lygerou Z, Perrakis A, Nishitani H. Hayashi A, et al. Among authors: hibbert rg. Life Sci Alliance. 2018 Dec 31;1(6):e201800238. doi: 10.26508/lsa.201800238. eCollection 2018 Dec. Life Sci Alliance. 2018. PMID: 30623174 Free PMC article.
Symmetry and asymmetry of the RING-RING dimer of Rad18.
Huang A, Hibbert RG, de Jong RN, Das D, Sixma TK, Boelens R. Huang A, et al. Among authors: hibbert rg. J Mol Biol. 2011 Jul 15;410(3):424-35. doi: 10.1016/j.jmb.2011.04.051. Epub 2011 Apr 27. J Mol Biol. 2011. PMID: 21549715
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