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p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis.
Cha-Molstad H, Yu JE, Feng Z, Lee SH, Kim JG, Yang P, Han B, Sung KW, Yoo YD, Hwang J, McGuire T, Shim SM, Song HD, Ganipisetti S, Wang N, Jang JM, Lee MJ, Kim SJ, Lee KH, Hong JT, Ciechanover A, Mook-Jung I, Kim KP, Xie XQ, Kwon YT, Kim BY. Cha-Molstad H, et al. Among authors: sung kw. Nat Commun. 2017 Jul 24;8(1):102. doi: 10.1038/s41467-017-00085-7. Nat Commun. 2017. PMID: 28740232 Free PMC article.
N-terminal arginylation generates a bimodal degron that modulates autophagic proteolysis.
Yoo YD, Mun SR, Ji CH, Sung KW, Kang KY, Heo AJ, Lee SH, An JY, Hwang J, Xie XQ, Ciechanover A, Kim BY, Kwon YT. Yoo YD, et al. Among authors: sung kw. Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):E2716-E2724. doi: 10.1073/pnas.1719110115. Epub 2018 Mar 5. Proc Natl Acad Sci U S A. 2018. PMID: 29507222 Free PMC article.
318 results