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Page 1
Exploring switch II pocket conformation of KRAS(G12D) with mutant-selective monobody inhibitors.
Akkapeddi P, Hattori T, Khan I, Glasser E, Koide A, Ketavarapu G, Whaby M, Zuberi M, Teng KW, Lefler J, Maso L, Bang I, Ostrowski MC, O'Bryan JP, Koide S. Akkapeddi P, et al. Among authors: ostrowski mc. Proc Natl Acad Sci U S A. 2023 Jul 11;120(28):e2302485120. doi: 10.1073/pnas.2302485120. Epub 2023 Jul 3. Proc Natl Acad Sci U S A. 2023. PMID: 37399416 Free PMC article.
The impact of inflammation and acute phase activation in cancer cachexia.
Robinson TP, Hamidi T, Counts B, Guttridge DC, Ostrowski MC, Zimmers TA, Koniaris LG. Robinson TP, et al. Among authors: ostrowski mc. Front Immunol. 2023 Oct 31;14:1207746. doi: 10.3389/fimmu.2023.1207746. eCollection 2023. Front Immunol. 2023. PMID: 38022578 Free PMC article. Review.
Profiling of collagen and extracellular matrix deposition from cell culture using in vitro ExtraCellular matrix mass spectrometry imaging (ivECM-MSI).
Zambrzycki SC, Saberi S, Biggs R, Eskandari N, Delisi D, Taylor H, Mehta AS, Drake RR, Gentile S, Bradshaw AD, Ostrowski M, Angel PM. Zambrzycki SC, et al. Matrix Biol Plus. 2024 Sep 25;24:100161. doi: 10.1016/j.mbplus.2024.100161. eCollection 2024 Dec. Matrix Biol Plus. 2024. PMID: 39435160 Free PMC article.
Cancer cachexia: involvement of an expanding macroenvironment.
Pryce BR, Wang DJ, Zimmers TA, Ostrowski MC, Guttridge DC. Pryce BR, et al. Among authors: ostrowski mc. Cancer Cell. 2023 Mar 13;41(3):581-584. doi: 10.1016/j.ccell.2023.02.007. Epub 2023 Mar 2. Cancer Cell. 2023. PMID: 36868225 Free PMC article.
Muscle inflammation is regulated by NF-κB from multiple cells to control distinct states of wasting in cancer cachexia.
Pryce BR, Oles A, Talbert EE, Romeo MJ, Vaena S, Sharma S, Spadafora V, Tolliver L, Mahvi DA, Morgan KA, Lancaster WP, Beal E, Koren N, Watts B, Overstreet M, Berto S, Subramanian S, Calisir K, Crawford A, Neelon B, Ostrowski MC, Zimmers TA, Tidball JG, Wang DJ, Guttridge DC. Pryce BR, et al. Among authors: ostrowski mc. Cell Rep. 2024 Nov 26;43(11):114925. doi: 10.1016/j.celrep.2024.114925. Epub 2024 Oct 30. Cell Rep. 2024. PMID: 39475511 Free article.
Hepatic protein kinase Cbeta deficiency mitigates late-onset obesity.
Shu Y, Gumma N, Hassan F, Branch DA, Baer LA, Ostrowski MC, Stanford KI, Baskin KK, Mehta KD. Shu Y, et al. Among authors: ostrowski mc. J Biol Chem. 2023 Aug;299(8):104917. doi: 10.1016/j.jbc.2023.104917. Epub 2023 Jun 12. J Biol Chem. 2023. PMID: 37315788 Free PMC article.
Pubertal exposure to dietary advanced glycation end products disrupts ductal morphogenesis and induces atypical hyperplasia in the mammary gland.
Krisanits BA, Schuster R, Randise J, Nogueira LM, Lane JT, Panguluri GA, Li H, Helke K, Cuitiño MC, Koivisto C, Spruill L, Ostrowski MC, Anderson SM, Turner DP, Findlay VJ. Krisanits BA, et al. Among authors: ostrowski mc. Breast Cancer Res. 2023 Oct 6;25(1):118. doi: 10.1186/s13058-023-01714-4. Breast Cancer Res. 2023. PMID: 37803429 Free PMC article.
The splanchnic mesenchyme is the tissue of origin for pancreatic fibroblasts during homeostasis and tumorigenesis.
Han L, Wu Y, Fang K, Sweeney S, Roesner UK, Parrish M, Patel K, Walter T, Piermattei J, Trimboli A, Lefler J, Timmers CD, Yu XZ, Jin VX, Zimmermann MT, Mathison AJ, Urrutia R, Ostrowski MC, Leone G. Han L, et al. Among authors: ostrowski mc. Nat Commun. 2023 Jan 3;14(1):1. doi: 10.1038/s41467-022-34464-6. Nat Commun. 2023. PMID: 36596776 Free PMC article.
STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer.
Lefler JE, MarElia-Bennett CB, Thies KA, Hildreth BE 3rd, Sharma SM, Pitarresi JR, Han L, Everett C, Koivisto C, Cuitino MC, Timmers CD, O'Quinn E, Parrish M, Romeo MJ, Linke AJ, Hobbs GA, Leone G, Guttridge DC, Zimmers TA, Lesinski GB, Ostrowski MC. Lefler JE, et al. Among authors: ostrowski mc. Life Sci Alliance. 2022 Jul 8;5(11):e202201460. doi: 10.26508/lsa.202201460. Print 2022 Nov. Life Sci Alliance. 2022. PMID: 35803738 Free PMC article.
170 results