Fagnant PM - Search Results

1

Double-headed binding of myosin II to F-actin shows the effect of strain on head structure.

Hojjatian A, Taylor DW, Daneshparvar N, Fagnant PM, Trybus KM, Taylor KA. Hojjatian A, et al. Among authors: fagnant pm. J Struct Biol. 2023 Sep;215(3):107995. doi: 10.1016/j.jsb.2023.107995. Epub 2023 Jul 4. J Struct Biol. 2023. PMID: 37414375 Free PMC article.

2

Role of the essential light chain in the activation of smooth muscle myosin by regulatory light chain phosphorylation.

Taylor KA, Feig M, Brooks CL 3rd, Fagnant PM, Lowey S, Trybus KM. Taylor KA, et al. Among authors: fagnant pm. J Struct Biol. 2014 Mar;185(3):375-82. doi: 10.1016/j.jsb.2013.12.008. Epub 2013 Dec 19. J Struct Biol. 2014. PMID: 24361582 Free PMC article.

3

The carboxyl-terminal isoforms of smooth muscle myosin heavy chain determine thick filament assembly properties.

Rovner AS, Fagnant PM, Lowey S, Trybus KM. Rovner AS, et al. Among authors: fagnant pm. J Cell Biol. 2002 Jan 7;156(1):113-23. doi: 10.1083/jcb.200107131. Epub 2002 Jan 7. J Cell Biol. 2002. PMID: 11781338 Free PMC article.

4

The two heads of smooth muscle myosin are enzymatically independent but mechanically interactive.

Rovner AS, Fagnant PM, Trybus KM. Rovner AS, et al. Among authors: fagnant pm. J Biol Chem. 2003 Jul 18;278(29):26938-45. doi: 10.1074/jbc.M303122200. Epub 2003 Apr 21. J Biol Chem. 2003. PMID: 12709440 Free article.

5

A mutant heterodimeric myosin with one inactive head generates maximal displacement.

Kad NM, Rovner AS, Fagnant PM, Joel PB, Kennedy GG, Patlak JB, Warshaw DM, Trybus KM. Kad NM, et al. Among authors: fagnant pm. J Cell Biol. 2003 Aug 4;162(3):481-8. doi: 10.1083/jcb.200304023. J Cell Biol. 2003. PMID: 12900396 Free PMC article.

6

Expression of a nonpolymerizable actin mutant in Sf9 cells.

Joel PB, Fagnant PM, Trybus KM. Joel PB, et al. Among authors: fagnant pm. Biochemistry. 2004 Sep 14;43(36):11554-9. doi: 10.1021/bi048899a. Biochemistry. 2004. PMID: 15350141

7

Phosphorylation of a single head of smooth muscle myosin activates the whole molecule.

Rovner AS, Fagnant PM, Trybus KM. Rovner AS, et al. Among authors: fagnant pm. Biochemistry. 2006 Apr 25;45(16):5280-9. doi: 10.1021/bi060154c. Biochemistry. 2006. PMID: 16618116 Free PMC article.

8

Mutation of a conserved glycine in the SH1-SH2 helix affects the load-dependent kinetics of myosin.

Kad NM, Patlak JB, Fagnant PM, Trybus KM, Warshaw DM. Kad NM, et al. Among authors: fagnant pm. Biophys J. 2007 Mar 1;92(5):1623-31. doi: 10.1529/biophysj.106.097618. Epub 2006 Dec 1. Biophys J. 2007. PMID: 17142278 Free PMC article.

9

Phosphorylated smooth muscle heavy meromyosin shows an open conformation linked to activation.

Baumann BA, Taylor DW, Huang Z, Tama F, Fagnant PM, Trybus KM, Taylor KA. Baumann BA, et al. Among authors: fagnant pm. J Mol Biol. 2012 Jan 13;415(2):274-87. doi: 10.1016/j.jmb.2011.10.047. Epub 2011 Nov 4. J Mol Biol. 2012. PMID: 22079364 Free PMC article.

10

Vascular disease-causing mutation R258C in ACTA2 disrupts actin dynamics and interaction with myosin.

Lu H, Fagnant PM, Bookwalter CS, Joel P, Trybus KM. Lu H, et al. Among authors: fagnant pm. Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):E4168-77. doi: 10.1073/pnas.1507587112. Epub 2015 Jul 7. Proc Natl Acad Sci U S A. 2015. PMID: 26153420 Free PMC article.

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