Keown JR - Search Results

1

Atomic structure of a nudivirus occlusion body protein determined from a 70-year-old crystal sample.

Keown JR, Crawshaw AD, Trincao J, Carrique L, Gildea RJ, Horrell S, Warren AJ, Axford D, Owen R, Evans G, Bézier A, Metcalf P, Grimes JM. Keown JR, et al. Nat Commun. 2023 Jul 13;14(1):4160. doi: 10.1038/s41467-023-39819-1. Nat Commun. 2023. PMID: 37443157 Free PMC article.

2

Plant DHDPR forms a dimer with unique secondary structure features that preclude higher-order assembly.

Watkin SAJ, Keown JR, Richards E, Goldstone DC, Devenish SRA, Grant Pearce F. Watkin SAJ, et al. Among authors: keown jr. Biochem J. 2018 Jan 5;475(1):137-150. doi: 10.1042/BCJ20170709. Biochem J. 2018. PMID: 29187521

3

The Protozoan Trichomonas vaginalis Targets Bacteria with Laterally Acquired NlpC/P60 Peptidoglycan Hydrolases.

Pinheiro J, Biboy J, Vollmer W, Hirt RP, Keown JR, Artuyants A, Black MM, Goldstone DC, Simoes-Barbosa A. Pinheiro J, et al. Among authors: keown jr. mBio. 2018 Dec 11;9(6):e01784-18. doi: 10.1128/mBio.01784-18. mBio. 2018. PMID: 30538181 Free PMC article.

4

Crystal structure of protein tyrosine phosphatase-2 from Cydia pomonella granulovirus.

Huang G, Oliver MR, Keown JR, Goldstone DC, Metcalf P. Huang G, et al. Among authors: keown jr. Acta Crystallogr F Struct Biol Commun. 2019 Apr 1;75(Pt 4):233-238. doi: 10.1107/S2053230X19002322. Epub 2019 Mar 13. Acta Crystallogr F Struct Biol Commun. 2019. PMID: 30950823 Free PMC article.

5

Structures of influenza A virus RNA polymerase offer insight into viral genome replication.

Fan H, Walker AP, Carrique L, Keown JR, Serna Martin I, Karia D, Sharps J, Hengrung N, Pardon E, Steyaert J, Grimes JM, Fodor E. Fan H, et al. Among authors: keown jr. Nature. 2019 Sep;573(7773):287-290. doi: 10.1038/s41586-019-1530-7. Epub 2019 Sep 4. Nature. 2019. PMID: 31485076 Free PMC article.

6

Design, Synthesis, and Biological Evaluation of Novel Indoles Targeting the Influenza PB2 Cap Binding Region.

McGowan DC, Balemans W, Embrechts W, Motte M, Keown JR, Buyck C, Corbera J, Funes M, Moreno L, Cooymans L, Tahri A, Eymard J, Stoops B, Strijbos R, Van den Berg J, Fodor E, Grimes JM, Koul A, Jonckers THM, Raboisson P, Guillemont J. McGowan DC, et al. Among authors: keown jr. J Med Chem. 2019 Nov 14;62(21):9680-9690. doi: 10.1021/acs.jmedchem.9b01091. Epub 2019 Oct 30. J Med Chem. 2019. PMID: 31647875 Free PMC article.

7

Enisamium is a small molecule inhibitor of the influenza A virus and SARS-CoV-2 RNA polymerases.

Walker AP, Fan H, Keown JR, Margitich V, Grimes JM, Fodor E, Te Velthuis AJW. Walker AP, et al. Among authors: keown jr. bioRxiv [Preprint]. 2020 Jan 6:2020.04.21.053017. doi: 10.1101/2020.04.21.053017. bioRxiv. 2020. PMID: 32511388 Free PMC article. Preprint.

8

Parallel evolution in the emergence of highly pathogenic avian influenza A viruses.

Escalera-Zamudio M, Golden M, Gutiérrez B, Thézé J, Keown JR, Carrique L, Bowden TA, Pybus OG. Escalera-Zamudio M, et al. Among authors: keown jr. Nat Commun. 2020 Nov 2;11(1):5511. doi: 10.1038/s41467-020-19364-x. Nat Commun. 2020. PMID: 33139731 Free PMC article.

9

Host ANP32A mediates the assembly of the influenza virus replicase.

Carrique L, Fan H, Walker AP, Keown JR, Sharps J, Staller E, Barclay WS, Fodor E, Grimes JM. Carrique L, et al. Among authors: keown jr. Nature. 2020 Nov;587(7835):638-643. doi: 10.1038/s41586-020-2927-z. Epub 2020 Nov 18. Nature. 2020. PMID: 33208942 Free PMC article.

10

Publisher Correction: Parallel evolution in the emergence of highly pathogenic avian influenza A viruses.

Escalera-Zamudio M, Golden M, Gutiérrez B, Thézé J, Keown JR, Carrique L, Bowden TA, Pybus OG. Escalera-Zamudio M, et al. Among authors: keown jr. Nat Commun. 2020 Nov 23;11(1):6070. doi: 10.1038/s41467-020-20006-5. Nat Commun. 2020. PMID: 33230170 Free PMC article.

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