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Targeting the SphK1/S1P/PFKFB3 axis suppresses hepatocellular carcinoma progression by disrupting glycolytic energy supply that drives tumor angiogenesis.
Liu XT, Huang Y, Liu D, Jiang YC, Zhao M, Chung LH, Han XD, Zhao Y, Chen J, Coleman P, Ting KK, Tran C, Su Y, Dennis CV, Bhatnagar A, Liu K, Don AS, Vadas MA, Gorrell MD, Zhang S, Murray M, Kavurma MM, McCaughan GW, Gamble JR, Qi Y. Liu XT, et al. Among authors: gamble jr. J Transl Med. 2024 Jan 10;22(1):43. doi: 10.1186/s12967-023-04830-z. J Transl Med. 2024. PMID: 38200582 Free PMC article.
The Role of the MiR-181 Family in Hepatocellular Carcinoma.
Chen J, Liu K, Vadas MA, Gamble JR, McCaughan GW. Chen J, et al. Among authors: gamble jr. Cells. 2024 Jul 31;13(15):1289. doi: 10.3390/cells13151289. Cells. 2024. PMID: 39120319 Free PMC article. Review.
Machine learning workflows identify a microRNA signature of insulin transcription in human tissues.
Wong WKM, Joglekar MV, Saini V, Jiang G, Dong CX, Chaitarvornkit A, Maciag GJ, Gerace D, Farr RJ, Satoor SN, Sahu S, Sharangdhar T, Ahmed AS, Chew YV, Liuwantara D, Heng B, Lim CK, Hunter J, Januszewski AS, Sørensen AE, Akil ASA, Gamble JR, Loudovaris T, Kay TW, Thomas HE, O'Connell PJ, Guillemin GJ, Martin D, Simpson AM, Hawthorne WJ, Dalgaard LT, Ma RCW, Hardikar AA. Wong WKM, et al. Among authors: gamble jr. iScience. 2021 Mar 31;24(4):102379. doi: 10.1016/j.isci.2021.102379. eCollection 2021 Apr 23. iScience. 2021. PMID: 33981968 Free PMC article.
Liver-specific deletion of miR-181ab1 reduces liver tumour progression via upregulation of CBX7.
Chen J, Zhao Y, Zhang F, Li J, Boland JA, Cheng NC, Liu K, Tiffen JC, Bertolino P, Bowen DG, Krueger A, Lisowski L, Alexander IE, Vadas MA, El-Omar E, Gamble JR, McCaughan GW. Chen J, et al. Among authors: gamble jr. Cell Mol Life Sci. 2022 Jul 22;79(8):443. doi: 10.1007/s00018-022-04452-6. Cell Mol Life Sci. 2022. PMID: 35867177 Free PMC article.
The aging endothelium.
Ting KK, Coleman P, Zhao Y, Vadas MA, Gamble JR. Ting KK, et al. Among authors: gamble jr. Vasc Biol. 2021 Jan 12;3(1):R35-R47. doi: 10.1530/VB-20-0013. eCollection 2021. Vasc Biol. 2021. PMID: 33880430 Free PMC article. Review.
192 results