Asano R - Search Results

1

Incorporation of a repeated polypeptide sequence in therapeutic antibodies as a universal masking procedure: A case study of T cell-engaging bispecific antibodies.

Maejima A, Suzuki S, Makabe K, Kumagai I, Asano R. Maejima A, et al. Among authors: asano r. N Biotechnol. 2023 Nov 25;77:80-89. doi: 10.1016/j.nbt.2023.07.004. Epub 2023 Jul 17. N Biotechnol. 2023. PMID: 37467927 Free article.

2

Functional construction of the anti-mucin core protein (MUC1) antibody MUSE11 variable regions in a bacterial expression system.

Asano R, Takemura S, Tsumoto K, Sakurai N, Teramae A, Ebara S, Katayose Y, Shinoda M, Suzuki M, Imai K, Matsuno S, Kudo T, Kumagai I. Asano R, et al. J Biochem. 2000 Apr;127(4):673-9. doi: 10.1093/oxfordjournals.jbchem.a022656. J Biochem. 2000. PMID: 10739961 Free article.

3

Functional Fv fragment of an antibody specific for CD28: Fv-mediated co-stimulation of T cells.

Takemura S, Asano R, Tsumoto K, Arai T, Sakurai N, Kodama H, Yoshida H, Katayose Y, Suzuki M, Matsuno S, Kudo T, Kumagai I. Takemura S, et al. Among authors: asano r. FEBS Lett. 2000 Jul 7;476(3):266-71. doi: 10.1016/s0014-5793(00)01741-5. FEBS Lett. 2000. PMID: 10913626 Free article.

4

Construction of a diabody (small recombinant bispecific antibody) using a refolding system.

Takemura S, Asano R, Tsumoto K, Ebara S, Sakurai N, Katayose Y, Kodama H, Yoshida H, Suzuki M, Imai K, Matsuno S, Kudo T, Kumagai I. Takemura S, et al. Among authors: asano r. Protein Eng. 2000 Aug;13(8):583-8. doi: 10.1093/protein/13.8.583. Protein Eng. 2000. PMID: 10964988

5

Mutated SEA-D227A-conjugated antibodies greatly enhance antitumor activity against MUC1-expressing bile duct carcinoma.

Kodama H, Suzuki M, Katayose Y, Shinoda M, Sakurai N, Takemura S, Yoshida H, Saeki H, Ichiyama M, Tsumoto K, Asano R, Kumagai I, Imai K, Hinoda Y, Matsuno S, Kudo T. Kodama H, et al. Among authors: asano r. Cancer Immunol Immunother. 2001 Dec;50(10):539-48. doi: 10.1007/s002620100219. Cancer Immunol Immunother. 2001. PMID: 11776376 Free PMC article.

6

A mutated superantigen SEA D227A fusion diabody specific to MUC1 and CD3 in targeted cancer immunotherapy for bile duct carcinoma.

Takemura S, Kudo T, Asano R, Suzuki M, Tsumoto K, Sakurai N, Katayose Y, Kodama H, Yoshida H, Ebara S, Saeki H, Imai K, Matsuno S, Kumagai I. Takemura S, et al. Among authors: asano r. Cancer Immunol Immunother. 2002 Mar;51(1):33-44. doi: 10.1007/s00262-001-0245-3. Epub 2002 Jan 11. Cancer Immunol Immunother. 2002. PMID: 11845258 Free PMC article.

7

T-cell immunotherapy for human MK-1-expressing tumors using a fusion protein of the superantigen SEA and anti-MK-1 scFv antibody.

Ueno A, Arakawa F, Abe H, Matsumoto H, Kudo T, Asano R, Tsumoto K, Kumagai I, Kuroki M, Kuroki M. Ueno A, et al. Among authors: asano r. Anticancer Res. 2002 Mar-Apr;22(2A):769-76. Anticancer Res. 2002. PMID: 12014649

8

Selection of human antibody fragments on the basis of stabilization of the variable domain in the presence of target antigens.

Watanabe H, Tsumoto K, Asano R, Nishimiya Y, Kumagai I. Watanabe H, et al. Among authors: asano r. Biochem Biophys Res Commun. 2002 Jul 5;295(1):31-6. doi: 10.1016/s0006-291x(02)00616-2. Biochem Biophys Res Commun. 2002. PMID: 12083762

9

Inhibition of hepatitis C virus NS3 protease by peptides derived from complementarity-determining regions (CDRs) of the monoclonal antibody 8D4: tolerance of a CDR peptide to conformational changes of a target.

Tsumoto K, Misawa S, Ohba Y, Ueno T, Hayashi H, Kasai N, Watanabe H, Asano R, Kumagai I. Tsumoto K, et al. Among authors: asano r. FEBS Lett. 2002 Aug 14;525(1-3):77-82. doi: 10.1016/s0014-5793(02)03090-9. FEBS Lett. 2002. PMID: 12163165 Free article.

10

Antitumor activity of interleukin-21 prepared by novel refolding procedure from inclusion bodies expressed in Escherichia coli.

Asano R, Kudo T, Makabe K, Tsumoto K, Kumagai I. Asano R, et al. FEBS Lett. 2002 Sep 25;528(1-3):70-6. doi: 10.1016/s0014-5793(02)03254-4. FEBS Lett. 2002. PMID: 12297282 Free article.

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