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Structural modeling of antibody variable regions using deep learning-progress and perspectives on drug discovery.
Jaszczyszyn I, Bielska W, Gawlowski T, Dudzic P, Satława T, Kończak J, Wilman W, Janusz B, Wróbel S, Chomicz D, Galson JD, Leem J, Kelm S, Krawczyk K. Jaszczyszyn I, et al. Among authors: leem j. Front Mol Biosci. 2023 Jul 7;10:1214424. doi: 10.3389/fmolb.2023.1214424. eCollection 2023. Front Mol Biosci. 2023. PMID: 37484529 Free PMC article. Review.
SAbDab: the structural antibody database.
Dunbar J, Krawczyk K, Leem J, Baker T, Fuchs A, Georges G, Shi J, Deane CM. Dunbar J, et al. Among authors: leem j. Nucleic Acids Res. 2014 Jan;42(Database issue):D1140-6. doi: 10.1093/nar/gkt1043. Epub 2013 Nov 8. Nucleic Acids Res. 2014. PMID: 24214988 Free PMC article.
SAbPred: a structure-based antibody prediction server.
Dunbar J, Krawczyk K, Leem J, Marks C, Nowak J, Regep C, Georges G, Kelm S, Popovic B, Deane CM. Dunbar J, et al. Among authors: leem j. Nucleic Acids Res. 2016 Jul 8;44(W1):W474-8. doi: 10.1093/nar/gkw361. Epub 2016 Apr 29. Nucleic Acids Res. 2016. PMID: 27131379 Free PMC article.
STCRDab: the structural T-cell receptor database.
Leem J, de Oliveira SHP, Krawczyk K, Deane CM. Leem J, et al. Nucleic Acids Res. 2018 Jan 4;46(D1):D406-D412. doi: 10.1093/nar/gkx971. Nucleic Acids Res. 2018. PMID: 29087479 Free PMC article.
Structurally Mapping Antibody Repertoires.
Krawczyk K, Kelm S, Kovaltsuk A, Galson JD, Kelly D, Trück J, Regep C, Leem J, Wong WK, Nowak J, Snowden J, Wright M, Starkie L, Scott-Tucker A, Shi J, Deane CM. Krawczyk K, et al. Among authors: leem j. Front Immunol. 2018 Jul 23;9:1698. doi: 10.3389/fimmu.2018.01698. eCollection 2018. Front Immunol. 2018. PMID: 30083160 Free PMC article.
SCALOP: sequence-based antibody canonical loop structure annotation.
Wong WK, Georges G, Ros F, Kelm S, Lewis AP, Taddese B, Leem J, Deane CM. Wong WK, et al. Among authors: leem j. Bioinformatics. 2019 May 15;35(10):1774-1776. doi: 10.1093/bioinformatics/bty877. Bioinformatics. 2019. PMID: 30321295 Free PMC article.
Building Representation Learning Models for Antibody Comprehension.
Barton J, Gaspariunas A, Galson JD, Leem J. Barton J, et al. Among authors: leem j. Cold Spring Harb Perspect Biol. 2024 Mar 1;16(3):a041462. doi: 10.1101/cshperspect.a041462. Cold Spring Harb Perspect Biol. 2024. PMID: 38012013 Review.
503 results