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Zika virus impairs growth in human neurospheres and brain organoids.
Garcez PP, Loiola EC, Madeiro da Costa R, Higa LM, Trindade P, Delvecchio R, Nascimento JM, Brindeiro R, Tanuri A, Rehen SK. Garcez PP, et al. Among authors: higa lm. Science. 2016 May 13;352(6287):816-8. doi: 10.1126/science.aaf6116. Epub 2016 Apr 10. Science. 2016. PMID: 27064148
Evidence for Transmission of Zika Virus by Platelet Transfusion.
Motta IJ, Spencer BR, Cordeiro da Silva SG, Arruda MB, Dobbin JA, Gonzaga YB, Arcuri IP, Tavares RC, Atta EH, Fernandes RF, Costa DA, Ribeiro LJ, Limonte F, Higa LM, Voloch CM, Brindeiro RM, Tanuri A, Ferreira OC Jr. Motta IJ, et al. Among authors: higa lm. N Engl J Med. 2016 Sep 15;375(11):1101-3. doi: 10.1056/NEJMc1607262. Epub 2016 Aug 17. N Engl J Med. 2016. PMID: 27532622 Free article. No abstract available.
Congenital Zika Virus Infection: Beyond Neonatal Microcephaly.
Melo AS, Aguiar RS, Amorim MM, Arruda MB, Melo FO, Ribeiro ST, Batista AG, Ferreira T, Dos Santos MP, Sampaio VV, Moura SR, Rabello LP, Gonzaga CE, Malinger G, Ximenes R, de Oliveira-Szejnfeld PS, Tovar-Moll F, Chimelli L, Silveira PP, Delvechio R, Higa L, Campanati L, Nogueira RM, Filippis AM, Szejnfeld J, Voloch CM, Ferreira OC Jr, Brindeiro RM, Tanuri A. Melo AS, et al. JAMA Neurol. 2016 Dec 1;73(12):1407-1416. doi: 10.1001/jamaneurol.2016.3720. JAMA Neurol. 2016. PMID: 27695855
Chloroquine, an Endocytosis Blocking Agent, Inhibits Zika Virus Infection in Different Cell Models.
Delvecchio R, Higa LM, Pezzuto P, Valadão AL, Garcez PP, Monteiro FL, Loiola EC, Dias AA, Silva FJ, Aliota MT, Caine EA, Osorio JE, Bellio M, O'Connor DH, Rehen S, de Aguiar RS, Savarino A, Campanati L, Tanuri A. Delvecchio R, et al. Among authors: higa lm. Viruses. 2016 Nov 29;8(12):322. doi: 10.3390/v8120322. Viruses. 2016. PMID: 27916837 Free PMC article.
Zika virus disrupts molecular fingerprinting of human neurospheres.
Garcez PP, Nascimento JM, de Vasconcelos JM, Madeiro da Costa R, Delvecchio R, Trindade P, Loiola EC, Higa LM, Cassoli JS, Vitória G, Sequeira PC, Sochacki J, Aguiar RS, Fuzii HT, de Filippis AM, da Silva Gonçalves Vianez Júnior JL, Tanuri A, Martins-de-Souza D, Rehen SK. Garcez PP, et al. Among authors: higa lm. Sci Rep. 2017 Jan 23;7:40780. doi: 10.1038/srep40780. Sci Rep. 2017. PMID: 28112162 Free PMC article.
Co-protoporphyrin IX and Sn-protoporphyrin IX inactivate Zika, Chikungunya and other arboviruses by targeting the viral envelope.
Neris RLS, Figueiredo CM, Higa LM, Araujo DF, Carvalho CAM, Verçoza BRF, Silva MOL, Carneiro FA, Tanuri A, Gomes AMO, Bozza MT, Da Poian AT, Cruz-Oliveira C, Assunção-Miranda I. Neris RLS, et al. Among authors: higa lm. Sci Rep. 2018 Jun 28;8(1):9805. doi: 10.1038/s41598-018-27855-7. Sci Rep. 2018. PMID: 29955082 Free PMC article.
Zika virus impairs the development of blood vessels in a mouse model of congenital infection.
Garcez PP, Stolp HB, Sravanam S, Christoff RR, Ferreira JCCG, Dias AA, Pezzuto P, Higa LM, Barbeito-Andrés J, Ferreira RO, Andrade CBV, Siqueira M, Santos TMP, Drumond J, Hoerder-Suabedissen A, de Lima CVF, Tovar-Moll F, Lopes RT, Fragel-Madeira L, Lent R, Ortiga-Carvalho TM, Stipursky J, Bellio M, Tanuri A, Molnár Z. Garcez PP, et al. Among authors: higa lm. Sci Rep. 2018 Aug 24;8(1):12774. doi: 10.1038/s41598-018-31149-3. Sci Rep. 2018. PMID: 30143723 Free PMC article.
Yellow fever virus is susceptible to sofosbuvir both in vitro and in vivo.
de Freitas CS, Higa LM, Sacramento CQ, Ferreira AC, Reis PA, Delvecchio R, Monteiro FL, Barbosa-Lima G, James Westgarth H, Vieira YR, Mattos M, Rocha N, Hoelz LVB, Leme RPP, Bastos MM, Rodrigues GOL, Lopes CEM, Queiroz-Junior CM, Lima CX, Costa VV, Teixeira MM, Bozza FA, Bozza PT, Boechat N, Tanuri A, Souza TML. de Freitas CS, et al. Among authors: higa lm. PLoS Negl Trop Dis. 2019 Jan 30;13(1):e0007072. doi: 10.1371/journal.pntd.0007072. eCollection 2019 Jan. PLoS Negl Trop Dis. 2019. PMID: 30699122 Free PMC article.
48 results