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A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity.
Liang S, Tran E, Du X, Dong J, Sudholz H, Chen H, Qu Z, Huntington ND, Babon JJ, Kershaw NJ, Zhang ZY, Baell JB, Wiede F, Tiganis T. Liang S, et al. Among authors: kershaw nj. Nat Commun. 2023 Jul 27;14(1):4524. doi: 10.1038/s41467-023-40170-8. Nat Commun. 2023. PMID: 37500611 Free PMC article.
Regulation of Janus kinases by SOCS proteins.
Kershaw NJ, Murphy JM, Lucet IS, Nicola NA, Babon JJ. Kershaw NJ, et al. Biochem Soc Trans. 2013 Aug;41(4):1042-7. doi: 10.1042/BST20130077. Biochem Soc Trans. 2013. PMID: 23863176 Free PMC article. Review.
Roquin binds microRNA-146a and Argonaute2 to regulate microRNA homeostasis.
Srivastava M, Duan G, Kershaw NJ, Athanasopoulos V, Yeo JH, Ose T, Hu D, Brown SH, Jergic S, Patel HR, Pratama A, Richards S, Verma A, Jones EY, Heissmeyer V, Preiss T, Dixon NE, Chong MM, Babon JJ, Vinuesa CG. Srivastava M, et al. Among authors: kershaw nj. Nat Commun. 2015 Feb 20;6:6253. doi: 10.1038/ncomms7253. Nat Commun. 2015. PMID: 25697406 Free PMC article.
VHL: Cullin-g the hypoxic response.
Kershaw NJ, Babon JJ. Kershaw NJ, et al. Structure. 2015 Mar 3;23(3):435-436. doi: 10.1016/j.str.2015.02.003. Structure. 2015. PMID: 25738382 Free article.
Attenuation of AMPK signaling by ROQUIN promotes T follicular helper cell formation.
Ramiscal RR, Parish IA, Lee-Young RS, Babon JJ, Blagih J, Pratama A, Martin J, Hawley N, Cappello JY, Nieto PF, Ellyard JI, Kershaw NJ, Sweet RA, Goodnow CC, Jones RG, Febbraio MA, Vinuesa CG, Athanasopoulos V. Ramiscal RR, et al. Among authors: kershaw nj. Elife. 2015 Oct 23;4:e08698. doi: 10.7554/eLife.08698. Elife. 2015. PMID: 26496200 Free PMC article.
JAK1 Takes a FERM Hold of Type II Cytokine Receptors.
Babon JJ, Liau NP, Kershaw NJ. Babon JJ, et al. Among authors: kershaw nj. Structure. 2016 Jun 7;24(6):840-2. doi: 10.1016/j.str.2016.05.007. Structure. 2016. PMID: 27276423 Free article.
56 results