Miles MA - Search Results

1

Molecular basis for nuclear accumulation and targeting of the inhibitor of apoptosis BIRC2.

Tencer AH, Yu Y, Causse SZ, Campbell GR, Klein BJ, Xuan H, Cartier J, Miles MA, Gaurav N, Zadoroznyj A, Holt TA, Wen H, Hawkins CJ, Spector SA, Dubrez L, Shi X, Kutateladze TG. Tencer AH, et al. Among authors: miles ma. Nat Struct Mol Biol. 2023 Sep;30(9):1265-1274. doi: 10.1038/s41594-023-01044-1. Epub 2023 Jul 31. Nat Struct Mol Biol. 2023. PMID: 37524969 Free PMC article.

2

Inhibition of Bcl-2 or IAP proteins does not provoke mutations in surviving cells.

Shekhar TM, Green MM, Rayner DM, Miles MA, Cutts SM, Hawkins CJ. Shekhar TM, et al. Among authors: miles ma. Mutat Res. 2015 Jul;777:23-32. doi: 10.1016/j.mrfmmm.2015.04.005. Epub 2015 Apr 15. Mutat Res. 2015. PMID: 25916945

3

TRAIL causes deletions at the HPRT and TK1 loci of clonogenically competent cells.

Miles MA, Shekhar TM, Hall NE, Hawkins CJ. Miles MA, et al. Mutat Res. 2016 May;787:15-31. doi: 10.1016/j.mrfmmm.2016.02.006. Epub 2016 Feb 18. Mutat Res. 2016. PMID: 26943263

4

IAP antagonists sensitize murine osteosarcoma cells to killing by TNFα.

Shekhar TM, Miles MA, Gupte A, Taylor S, Tascone B, Walkley CR, Hawkins CJ. Shekhar TM, et al. Among authors: miles ma. Oncotarget. 2016 Jun 7;7(23):33866-86. doi: 10.18632/oncotarget.8980. Oncotarget. 2016. PMID: 27129149 Free PMC article.

5

Old and Novel Functions of Caspase-2.

Miles MA, Kitevska-Ilioski T, Hawkins CJ. Miles MA, et al. Int Rev Cell Mol Biol. 2017;332:155-212. doi: 10.1016/bs.ircmb.2016.12.002. Epub 2017 Jan 27. Int Rev Cell Mol Biol. 2017. PMID: 28526132 Review.

6

Executioner caspases and CAD are essential for mutagenesis induced by TRAIL or vincristine.

Miles MA, Hawkins CJ. Miles MA, et al. Cell Death Dis. 2017 Oct 5;8(10):e3062. doi: 10.1038/cddis.2017.454. Cell Death Dis. 2017. PMID: 28981092 Free PMC article.

7

Mutagenic assessment of chemotherapy and Smac mimetic drugs in cells with defective DNA damage response pathways.

Miles MA, Hawkins CJ. Miles MA, et al. Sci Rep. 2018 Sep 26;8(1):14421. doi: 10.1038/s41598-018-32517-9. Sci Rep. 2018. PMID: 30258062 Free PMC article.

8

CrmA orthologs from diverse poxviruses potently inhibit caspases-1 and -8, yet cleavage site mutagenesis frequently produces caspase-1-specific variants.

Bloomer DT, Kitevska-Ilioski T, Pantaki-Eimany D, Ji Y, Miles MA, Heras B, Hawkins CJ. Bloomer DT, et al. Among authors: miles ma. Biochem J. 2019 May 7;476(9):1335-1357. doi: 10.1042/BCJ20190202. Biochem J. 2019. PMID: 30992316

9

Proteasome inhibitors trigger mutations via activation of caspases and CAD, but mutagenesis provoked by the HDAC inhibitors vorinostat and romidepsin is caspase/CAD-independent.

Miles MA, Harris MA, Hawkins CJ. Miles MA, et al. Apoptosis. 2019 Jun;24(5-6):404-413. doi: 10.1007/s10495-019-01543-x. Apoptosis. 2019. PMID: 30997620

10

Plexin B2 Is a Regulator of Monocyte Apoptotic Cell Disassembly.

Atkin-Smith GK, Miles MA, Tixeira R, Lay FT, Duan M, Hawkins CJ, Phan TK, Paone S, Mathivanan S, Hulett MD, Chen W, Poon IKH. Atkin-Smith GK, et al. Among authors: miles ma. Cell Rep. 2019 Nov 12;29(7):1821-1831.e3. doi: 10.1016/j.celrep.2019.10.014. Cell Rep. 2019. PMID: 31722200 Free article.

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