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Comparative Safety and Effectiveness of Biologic Therapy for Crohn's Disease: A CA-IBD Cohort Study.
Singh S, Kim J, Luo J, Paul P, Rudrapatna V, Park S, Zheng K, Syal G, Ha C, Fleshner P, McGovern D, Sauk JS, Limketkai B, Dulai PS, Boland BS, Eisenstein S, Ramamoorthy S, Melmed G, Mahadevan U, Sandborn WJ, Ohno-Machado L. Singh S, et al. Among authors: mcgovern d. Clin Gastroenterol Hepatol. 2023 Aug;21(9):2359-2369.e5. doi: 10.1016/j.cgh.2022.10.029. Epub 2022 Nov 5. Clin Gastroenterol Hepatol. 2023. PMID: 36343846
Use of animal models in elucidating disease pathogenesis in IBD.
Khanna PV, Shih DQ, Haritunians T, McGovern DP, Targan S. Khanna PV, et al. Semin Immunopathol. 2014 Sep;36(5):541-51. doi: 10.1007/s00281-014-0444-6. Epub 2014 Sep 12. Semin Immunopathol. 2014. PMID: 25212688 Free PMC article. Review.
Profiling immune cell tissue niches in the spatial "omics" era.
Lee CY, McCaffrey J, McGovern D, Clatworthy MR. Lee CY, et al. Among authors: mcgovern d. J Allergy Clin Immunol. 2024 Nov 8:S0091-6749(24)01178-3. doi: 10.1016/j.jaci.2024.11.001. Online ahead of print. J Allergy Clin Immunol. 2024. PMID: 39522655 Free article. Review.
Macrophage LRRK2 hyperactivity impairs autophagy and induces Paneth cell dysfunction.
Sun S, Hodel M, Wang X, De Vicente J, Haritunians T, Debebe A, Hung CT, Ma C, Malique A, Nguyen HN, Agam M, Maloney MT, Goo MS, Kluss JH, Mishra R, Frein J, Foster A, Ballentine S, Pandey U, Kern J, Yang S, Mengesha E, Balasubramanian I, Arguello A, Estrada AA, Gao N, Peter I, McGovern DPB, Henry AG, Stappenbeck TS, Liu TC. Sun S, et al. Among authors: mcgovern dpb. Sci Immunol. 2024 Nov 8;9(101):eadi7907. doi: 10.1126/sciimmunol.adi7907. Epub 2024 Nov 8. Sci Immunol. 2024. PMID: 39514635
A Proteomics Pipeline for Generating Clinical Grade Biomarker Candidates from Data-Independent Acquisition Mass Spectrometry (DIA-MS) Discovery.
Fu Q, Vegesna M, Sundararaman N, Damoc E, Arrey TN, Pashkova A, Mengesha E, Debbas P, Joung S, Li D, Cheng S, Braun J, McGovern DPB, Murray CI, Xuan Y, Van Eyk JE. Fu Q, et al. Among authors: mcgovern dpb. Angew Chem Int Ed Engl. 2024 Oct 21:e202409446. doi: 10.1002/anie.202409446. Online ahead of print. Angew Chem Int Ed Engl. 2024. PMID: 39432331
The JAK inhibitor, Tofacitinib, Corrects the Overexpression of CEACAM6 and Limits Susceptibility to AIEC Caused by Reduced Activity of the IBD Associated Gene, PTPN2.
Chatterjee P, Canale V, King SJ, Shawki A, Lei H, Haddad M, Gries CM, McGovern DPB, Borneman J, McCole DF. Chatterjee P, et al. Among authors: mcgovern dpb. medRxiv [Preprint]. 2024 Sep 28:2024.09.26.24314341. doi: 10.1101/2024.09.26.24314341. medRxiv. 2024. PMID: 39399045 Free PMC article. Preprint.
417 results