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Page 1
The Rad51 paralogs facilitate a novel DNA strand specific damage tolerance pathway.
Rosenbaum JC, Bonilla B, Hengel SR, Mertz TM, Herken BW, Kazemier HG, Pressimone CA, Ratterman TC, MacNary E, De Magis A, Kwon Y, Godin SK, Van Houten B, Normolle DP, Sung P, Das SR, Paeschke K, Roberts SA, VanDemark AP, Bernstein KA. Rosenbaum JC, et al. Nat Commun. 2019 Aug 5;10(1):3515. doi: 10.1038/s41467-019-11374-8. Nat Commun. 2019. PMID: 31383866 Free PMC article.
Xenopus laevis lack the critical sperm factor PLCζ.
Bainbridge RE, Rosenbaum JC, Sau P, Carlson AE. Bainbridge RE, et al. Among authors: rosenbaum jc. bioRxiv [Preprint]. 2023 Feb 3:2023.02.02.526858. doi: 10.1101/2023.02.02.526858. bioRxiv. 2023. PMID: 36778253 Free PMC article. Preprint.
Inactivation of RIP3 kinase sensitizes to 15LOX/PEBP1-mediated ferroptotic death.
Lamade AM, Wu L, Dar HH, Mentrup HL, Shrivastava IH, Epperly MW, St Croix CM, Tyurina YY, Anthonymuthu TS, Yang Q, Kapralov AA, Huang Z, Mao G, Amoscato AA, Hier ZE, Artyukhova MA, Shurin G, Rosenbaum JC, Gough PJ, Bertin J, VanDemark AP, Watkins SC, Mollen KP, Bahar I, Greenberger JS, Kagan VE, Whalen MJ, Bayır H. Lamade AM, et al. Among authors: rosenbaum jc. Redox Biol. 2022 Apr;50:102232. doi: 10.1016/j.redox.2022.102232. Epub 2022 Jan 10. Redox Biol. 2022. PMID: 35101798 Free PMC article.
PEBP1 acts as a rheostat between prosurvival autophagy and ferroptotic death in asthmatic epithelial cells.
Zhao J, Dar HH, Deng Y, St Croix CM, Li Z, Minami Y, Shrivastava IH, Tyurina YY, Etling E, Rosenbaum JC, Nagasaki T, Trudeau JB, Watkins SC, Bahar I, Bayır H, VanDemark AP, Kagan VE, Wenzel SE. Zhao J, et al. Among authors: rosenbaum jc. Proc Natl Acad Sci U S A. 2020 Jun 23;117(25):14376-14385. doi: 10.1073/pnas.1921618117. Epub 2020 Jun 8. Proc Natl Acad Sci U S A. 2020. PMID: 32513718 Free PMC article.
Empowerment of 15-Lipoxygenase Catalytic Competence in Selective Oxidation of Membrane ETE-PE to Ferroptotic Death Signals, HpETE-PE.
Anthonymuthu TS, Kenny EM, Shrivastava I, Tyurina YY, Hier ZE, Ting HC, Dar HH, Tyurin VA, Nesterova A, Amoscato AA, Mikulska-Ruminska K, Rosenbaum JC, Mao G, Zhao J, Conrad M, Kellum JA, Wenzel SE, VanDemark AP, Bahar I, Kagan VE, Bayır H. Anthonymuthu TS, et al. Among authors: rosenbaum jc. J Am Chem Soc. 2018 Dec 26;140(51):17835-17839. doi: 10.1021/jacs.8b09913. Epub 2018 Dec 17. J Am Chem Soc. 2018. PMID: 30525572 Free PMC article.
PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals.
Wenzel SE, Tyurina YY, Zhao J, St Croix CM, Dar HH, Mao G, Tyurin VA, Anthonymuthu TS, Kapralov AA, Amoscato AA, Mikulska-Ruminska K, Shrivastava IH, Kenny EM, Yang Q, Rosenbaum JC, Sparvero LJ, Emlet DR, Wen X, Minami Y, Qu F, Watkins SC, Holman TR, VanDemark AP, Kellum JA, Bahar I, Bayır H, Kagan VE. Wenzel SE, et al. Among authors: rosenbaum jc. Cell. 2017 Oct 19;171(3):628-641.e26. doi: 10.1016/j.cell.2017.09.044. Cell. 2017. PMID: 29053969 Free PMC article.
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