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Page 1
Specific quinone reductase 2 inhibitors reduce metabolic burden and reverse Alzheimer's disease phenotype in mice.
Gould NL, Scherer GR, Carvalho S, Shurrush K, Kayyal H, Edry E, Elkobi A, David O, Foqara M, Thakar D, Pavesi T, Sharma V, Walker M, Maitland M, Dym O, Albeck S, Peleg Y, Germain N, Babaev I, Sharir H, Lalzar M, Shklyar B, Hazut N, Khamaisy M, Lévesque M, Lajoie G, Avoli M, Amitai G, Lefker B, Subramanyam C, Shilton B, Barr H, Rosenblum K. Gould NL, et al. Among authors: dym o. J Clin Invest. 2023 Oct 2;133(19):e162120. doi: 10.1172/JCI162120. J Clin Invest. 2023. PMID: 37561584 Free PMC article.
The impact of molecular variants, crystallization conditions and the space group on ligand-protein complexes: a case study on bacterial phosphotriesterase.
Dym O, Aggarwal N, Ashani Y, Leader H, Albeck S, Unger T, Hamer-Rogotner S, Silman I, Tawfik DS, Sussman JL. Dym O, et al. Acta Crystallogr D Struct Biol. 2023 Nov 1;79(Pt 11):992-1009. doi: 10.1107/S2059798323007672. Epub 2023 Oct 20. Acta Crystallogr D Struct Biol. 2023. PMID: 37860961 Free PMC article.
Diversity of CysD domains in gel-forming mucins.
Khmelnitsky L, Milo A, Dym O, Fass D. Khmelnitsky L, et al. Among authors: dym o. FEBS J. 2023 Nov;290(21):5196-5203. doi: 10.1111/febs.16918. Epub 2023 Aug 11. FEBS J. 2023. PMID: 37526947 Free article.
VWD domain stabilization by autocatalytic Asp-Pro cleavage.
Yeshaya N, Gupta PK, Dym O, Morgenstern D, Major DT, Fass D. Yeshaya N, et al. Among authors: dym o. Protein Sci. 2024 Mar;33(3):e4929. doi: 10.1002/pro.4929. Protein Sci. 2024. PMID: 38380729 Free PMC article.
Stable Mammalian Serum Albumins Designed for Bacterial Expression.
Khersonsky O, Goldsmith M, Zaretsky I, Hamer-Rogotner S, Dym O, Unger T, Yona M, Fridmann-Sirkis Y, Fleishman SJ. Khersonsky O, et al. Among authors: dym o. J Mol Biol. 2023 Sep 1;435(17):168191. doi: 10.1016/j.jmb.2023.168191. Epub 2023 Jun 28. J Mol Biol. 2023. PMID: 37385581
Design of a stable human acid-β-glucosidase: towards improved Gaucher disease therapy and mutation classification.
Pokorna S, Khersonsky O, Lipsh-Sokolik R, Goldenzweig A, Nielsen R, Ashani Y, Peleg Y, Unger T, Albeck S, Dym O, Tirosh A, Tarayra R, Hocquemiller M, Laufer R, Ben-Dor S, Silman I, Sussman JL, Fleishman SJ, Futerman AH. Pokorna S, et al. Among authors: dym o. FEBS J. 2023 Jul;290(13):3383-3399. doi: 10.1111/febs.16758. Epub 2023 Mar 23. FEBS J. 2023. PMID: 36808692 Free article.
83 results