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Advancing translational research for colorectal immuno-oncology.
Thomas EM, Wright JA, Blake SJ, Page AJ, Worthley DL, Woods SL. Thomas EM, et al. Among authors: woods sl. Br J Cancer. 2023 Oct;129(9):1442-1450. doi: 10.1038/s41416-023-02392-x. Epub 2023 Aug 10. Br J Cancer. 2023. PMID: 37563222 Free PMC article. Review.
Point Mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant.
Li J, Woods SL, Healey S, Beesley J, Chen X, Lee JS, Sivakumaran H, Wayte N, Nones K, Waterfall JJ, Pearson J, Patch AM, Senz J, Ferreira MA, Kaurah P, Mackenzie R, Heravi-Moussavi A, Hansford S, Lannagan TRM, Spurdle AB, Simpson PT, da Silva L, Lakhani SR, Clouston AD, Bettington M, Grimpen F, Busuttil RA, Di Costanzo N, Boussioutas A, Jeanjean M, Chong G, Fabre A, Olschwang S, Faulkner GJ, Bellos E, Coin L, Rioux K, Bathe OF, Wen X, Martin HC, Neklason DW, Davis SR, Walker RL, Calzone KA, Avital I, Heller T, Koh C, Pineda M, Rudloff U, Quezado M, Pichurin PN, Hulick PJ, Weissman SM, Newlin A, Rubinstein WS, Sampson JE, Hamman K, Goldgar D, Poplawski N, Phillips K, Schofield L, Armstrong J, Kiraly-Borri C, Suthers GK, Huntsman DG, Foulkes WD, Carneiro F, Lindor NM, Edwards SL, French JD, Waddell N, Meltzer PS, Worthley DL, Schrader KA, Chenevix-Trench G. Li J, et al. Among authors: woods sl. Am J Hum Genet. 2016 May 5;98(5):830-842. doi: 10.1016/j.ajhg.2016.03.001. Epub 2016 Apr 14. Am J Hum Genet. 2016. PMID: 27087319 Free PMC article.
Oncogenic BRAF mutation induces DNA methylation changes in a murine model for human serrated colorectal neoplasia.
Bond CE, Liu C, Kawamata F, McKeone DM, Fernando W, Jamieson S, Pearson SA, Kane A, Woods SL, Lannagan TRM, Somashekar R, Lee Y, Dumenil T, Hartel G, Spring KJ, Borowsky J, Fennell L, Bettington M, Lee J, Worthley DL, Leggett BA, Whitehall VLJ. Bond CE, et al. Among authors: woods sl. Epigenetics. 2018;13(1):40-48. doi: 10.1080/15592294.2017.1411446. Epub 2018 Feb 19. Epigenetics. 2018. PMID: 29235923 Free PMC article.
Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis.
Lannagan TRM, Lee YK, Wang T, Roper J, Bettington ML, Fennell L, Vrbanac L, Jonavicius L, Somashekar R, Gieniec K, Yang M, Ng JQ, Suzuki N, Ichinose M, Wright JA, Kobayashi H, Putoczki TL, Hayakawa Y, Leedham SJ, Abud HE, Yilmaz ÖH, Marker J, Klebe S, Wirapati P, Mukherjee S, Tejpar S, Leggett BA, Whitehall VLJ, Worthley DL, Woods SL. Lannagan TRM, et al. Among authors: woods sl. Gut. 2019 Apr;68(4):684-692. doi: 10.1136/gutjnl-2017-315920. Epub 2018 Apr 17. Gut. 2019. PMID: 29666172 Free PMC article.
Alpha-Blockers As Colorectal Cancer Chemopreventive: Findings from a Case-Control Study, Human Cell Cultures, and In Vivo Preclinical Testing.
Suzuki N, Niikura R, Ihara S, Hikiba Y, Kinoshita H, Higashishima N, Hayakawa Y, Yamada A, Hirata Y, Nakata R, Okamoto M, Sano M, Kushiyama A, Ichinose M, Woods SL, Worthley D, Iwamoto Y, Koike K. Suzuki N, et al. Among authors: woods sl. Cancer Prev Res (Phila). 2019 Mar;12(3):185-194. doi: 10.1158/1940-6207.CAPR-18-0288. Epub 2019 Jan 30. Cancer Prev Res (Phila). 2019. PMID: 30700439
Cancer-associated fibroblasts in gastrointestinal cancer.
Kobayashi H, Enomoto A, Woods SL, Burt AD, Takahashi M, Worthley DL. Kobayashi H, et al. Among authors: woods sl. Nat Rev Gastroenterol Hepatol. 2019 May;16(5):282-295. doi: 10.1038/s41575-019-0115-0. Nat Rev Gastroenterol Hepatol. 2019. PMID: 30778141 Review.
Cancer-associated fibroblasts-heroes or villains?
Gieniec KA, Butler LM, Worthley DL, Woods SL. Gieniec KA, et al. Among authors: woods sl. Br J Cancer. 2019 Aug;121(4):293-302. doi: 10.1038/s41416-019-0509-3. Epub 2019 Jul 10. Br J Cancer. 2019. PMID: 31289350 Free PMC article. Review.
Meflin-Positive Cancer-Associated Fibroblasts Inhibit Pancreatic Carcinogenesis.
Mizutani Y, Kobayashi H, Iida T, Asai N, Masamune A, Hara A, Esaki N, Ushida K, Mii S, Shiraki Y, Ando K, Weng L, Ishihara S, Ponik SM, Conklin MW, Haga H, Nagasaka A, Miyata T, Matsuyama M, Kobayashi T, Fujii T, Yamada S, Yamaguchi J, Wang T, Woods SL, Worthley D, Shimamura T, Fujishiro M, Hirooka Y, Enomoto A, Takahashi M. Mizutani Y, et al. Among authors: woods sl. Cancer Res. 2019 Oct 15;79(20):5367-5381. doi: 10.1158/0008-5472.CAN-19-0454. Epub 2019 Aug 22. Cancer Res. 2019. PMID: 31439548
Exploiting differential Wnt target gene expression to generate a molecular biomarker for colorectal cancer stratification.
Kleeman SO, Koelzer VH, Jones HJ, Vazquez EG, Davis H, East JE, Arnold R, Koppens MA, Blake A, Domingo E, Cunningham C, Beggs AD, Pestinger V, Loughrey MB, Wang LM, Lannagan TR, Woods SL, Worthley D, Consortium SC, Tomlinson I, Dunne PD, Maughan T, Leedham SJ. Kleeman SO, et al. Among authors: woods sl. Gut. 2020 Jun;69(6):1092-1103. doi: 10.1136/gutjnl-2019-319126. Epub 2019 Sep 28. Gut. 2020. PMID: 31563876 Free PMC article.
94 results