Copeland WC - Search Results

1

Structure-specific roles for PolG2-DNA complexes in maintenance and replication of mitochondrial DNA.

Wojtaszek JL, Hoff KE, Longley MJ, Kaur P, Andres SN, Wang H, Williams RS, Copeland WC. Wojtaszek JL, et al. Among authors: copeland wc. Nucleic Acids Res. 2023 Oct 13;51(18):9716-9732. doi: 10.1093/nar/gkad679. Nucleic Acids Res. 2023. PMID: 37592734 Free PMC article.

2

Characterization of the native and recombinant catalytic subunit of human DNA polymerase gamma: identification of residues critical for exonuclease activity and dideoxynucleotide sensitivity.

Longley MJ, Ropp PA, Lim SE, Copeland WC. Longley MJ, et al. Among authors: copeland wc. Biochemistry. 1998 Jul 21;37(29):10529-39. doi: 10.1021/bi980772w. Biochemistry. 1998. PMID: 9671525

3

Identification of 5'-deoxyribose phosphate lyase activity in human DNA polymerase gamma and its role in mitochondrial base excision repair in vitro.

Longley MJ, Prasad R, Srivastava DK, Wilson SH, Copeland WC. Longley MJ, et al. Among authors: copeland wc. Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12244-8. doi: 10.1073/pnas.95.21.12244. Proc Natl Acad Sci U S A. 1998. PMID: 9770471 Free PMC article.

4

The mitochondrial p55 accessory subunit of human DNA polymerase gamma enhances DNA binding, promotes processive DNA synthesis, and confers N-ethylmaleimide resistance.

Lim SE, Longley MJ, Copeland WC. Lim SE, et al. Among authors: copeland wc. J Biol Chem. 1999 Dec 31;274(53):38197-203. doi: 10.1074/jbc.274.53.38197. J Biol Chem. 1999. PMID: 10608893 Free article.

5

The fidelity of human DNA polymerase gamma with and without exonucleolytic proofreading and the p55 accessory subunit.

Longley MJ, Nguyen D, Kunkel TA, Copeland WC. Longley MJ, et al. Among authors: copeland wc. J Biol Chem. 2001 Oct 19;276(42):38555-62. doi: 10.1074/jbc.M105230200. Epub 2001 Aug 14. J Biol Chem. 2001. PMID: 11504725 Free article.

6

Active site mutation in DNA polymerase gamma associated with progressive external ophthalmoplegia causes error-prone DNA synthesis.

Ponamarev MV, Longley MJ, Nguyen D, Kunkel TA, Copeland WC. Ponamarev MV, et al. Among authors: copeland wc. J Biol Chem. 2002 May 3;277(18):15225-8. doi: 10.1074/jbc.C200100200. Epub 2002 Mar 15. J Biol Chem. 2002. PMID: 11897778 Free article.

7

Purification, separation, and identification of the human mtDNA polymerase with and without its accessory subunit.

Longley MJ, Copeland WC. Longley MJ, et al. Among authors: copeland wc. Methods Mol Biol. 2002;197:245-57. doi: 10.1385/1-59259-284-8:245. Methods Mol Biol. 2002. PMID: 12013800 No abstract available.

8

The mitochondrial DNA polymerase as a target of oxidative damage.

Graziewicz MA, Day BJ, Copeland WC. Graziewicz MA, et al. Among authors: copeland wc. Nucleic Acids Res. 2002 Jul 1;30(13):2817-24. doi: 10.1093/nar/gkf392. Nucleic Acids Res. 2002. PMID: 12087165 Free PMC article.

9

Mutations in DNA polymerase gamma cause error prone DNA synthesis in human mitochondrial disorders.

Copeland WC, Ponamarev MV, Nguyen D, Kunkel TA, Longley MJ. Copeland WC, et al. Acta Biochim Pol. 2003;50(1):155-67. Acta Biochim Pol. 2003. PMID: 12673356 Review.

10

Structural determinants in human DNA polymerase gamma account for mitochondrial toxicity from nucleoside analogs.

Lim SE, Ponamarev MV, Longley MJ, Copeland WC. Lim SE, et al. Among authors: copeland wc. J Mol Biol. 2003 May 23;329(1):45-57. doi: 10.1016/s0022-2836(03)00405-4. J Mol Biol. 2003. PMID: 12742017

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