Saha S - Search Results

1

R-loops, type I topoisomerases and cancer.

Saha S, Pommier Y. Saha S, et al. NAR Cancer. 2023 Mar 3;5(1):zcad013. doi: 10.1093/narcan/zcad013. eCollection 2023 Mar. NAR Cancer. 2023. PMID: 37600974 Free PMC article.

2

Synthesis and structure-activity relationship of furoquinolinediones as inhibitors of Tyrosyl-DNA phosphodiesterase 2 (TDP2).

Yu LM, Hu Z, Chen Y, Ravji A, Lopez S, Plescia CB, Yu Q, Yang H, Abdelmalak M, Saha S, Agama K, Kiselev E, Marchand C, Pommier Y, An LK. Yu LM, et al. Among authors: saha s. Eur J Med Chem. 2018 May 10;151:777-796. doi: 10.1016/j.ejmech.2018.04.024. Epub 2018 Apr 12. Eur J Med Chem. 2018. PMID: 29677635 Free PMC article.

3

Excision repair of topoisomerase DNA-protein crosslinks (TOP-DPC).

Sun Y, Saha S, Wang W, Saha LK, Huang SN, Pommier Y. Sun Y, et al. Among authors: saha lk, saha s. DNA Repair (Amst). 2020 May;89:102837. doi: 10.1016/j.dnarep.2020.102837. Epub 2020 Mar 7. DNA Repair (Amst). 2020. PMID: 32200233 Free PMC article. Review.

4

Debulking of topoisomerase DNA-protein crosslinks (TOP-DPC) by the proteasome, non-proteasomal and non-proteolytic pathways.

Sun Y, Saha LK, Saha S, Jo U, Pommier Y. Sun Y, et al. Among authors: saha lk, saha s. DNA Repair (Amst). 2020 Oct;94:102926. doi: 10.1016/j.dnarep.2020.102926. Epub 2020 Jul 10. DNA Repair (Amst). 2020. PMID: 32674013 Free PMC article. Review.

5

DNA and RNA Cleavage Complexes and Repair Pathway for TOP3B RNA- and DNA-Protein Crosslinks.

Saha S, Sun Y, Huang SN, Baechler SA, Pongor LS, Agama K, Jo U, Zhang H, Tse-Dinh YC, Pommier Y. Saha S, et al. Cell Rep. 2020 Dec 29;33(13):108569. doi: 10.1016/j.celrep.2020.108569. Cell Rep. 2020. PMID: 33378676 Free PMC article.

6

PARylation prevents the proteasomal degradation of topoisomerase I DNA-protein crosslinks and induces their deubiquitylation.

Sun Y, Chen J, Huang SN, Su YP, Wang W, Agama K, Saha S, Jenkins LM, Pascal JM, Pommier Y. Sun Y, et al. Among authors: saha s. Nat Commun. 2021 Aug 18;12(1):5010. doi: 10.1038/s41467-021-25252-9. Nat Commun. 2021. PMID: 34408146 Free PMC article.

7

Replication-dependent cytotoxicity and Spartan-mediated repair of trapped PARP1-DNA complexes.

Saha LK, Murai Y, Saha S, Jo U, Tsuda M, Takeda S, Pommier Y. Saha LK, et al. Among authors: saha s. Nucleic Acids Res. 2021 Oct 11;49(18):10493-10506. doi: 10.1093/nar/gkab777. Nucleic Acids Res. 2021. PMID: 34551432 Free PMC article.

8

Resolution of R-loops by topoisomerase III-β (TOP3B) in coordination with the DEAD-box helicase DDX5.

Saha S, Yang X, Huang SN, Agama K, Baechler SA, Sun Y, Zhang H, Saha LK, Su S, Jenkins LM, Wang W, Pommier Y. Saha S, et al. Among authors: saha lk. Cell Rep. 2022 Jul 12;40(2):111067. doi: 10.1016/j.celrep.2022.111067. Cell Rep. 2022. PMID: 35830799 Free PMC article.

9

Structural and biochemical basis for DNA and RNA catalysis by human Topoisomerase 3β.

Yang X, Saha S, Yang W, Neuman KC, Pommier Y. Yang X, et al. Among authors: saha s. Nat Commun. 2022 Aug 9;13(1):4656. doi: 10.1038/s41467-022-32221-3. Nat Commun. 2022. PMID: 35945419 Free PMC article.

10

Replication-associated formation and repair of human topoisomerase IIIα cleavage complexes.

Saha LK, Saha S, Yang X, Huang SN, Sun Y, Jo U, Pommier Y. Saha LK, et al. Among authors: saha s. Nat Commun. 2023 Apr 6;14(1):1925. doi: 10.1038/s41467-023-37498-6. Nat Commun. 2023. PMID: 37024461 Free PMC article.

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