Gao ZG - Search Results

1

Structure-Activity Relationship of Truncated 2,8-Disubstituted-Adenosine Derivatives as Dual A_2A/A₃ Adenosine Receptor Antagonists and Their Cancer Immunotherapeutic Activity.

Kim G, Hou X, Byun WS, Kim G, Jarhad DB, Lee G, Hyun YE, Yu J, Lee CS, Qu S, Warnick E, Gao ZG, Kim JY, Ji S, Shin H, Choi JR, Jacobson KA, Lee HW, Lee SK, Jeong LS. Kim G, et al. Among authors: gao zg. J Med Chem. 2023 Sep 14;66(17):12249-12265. doi: 10.1021/acs.jmedchem.3c00806. Epub 2023 Aug 21. J Med Chem. 2023. PMID: 37603705 Free PMC article.

2

Identification by site-directed mutagenesis of residues involved in ligand recognition and activation of the human A3 adenosine receptor.

Gao ZG, Chen A, Barak D, Kim SK, Müller CE, Jacobson KA. Gao ZG, et al. J Biol Chem. 2002 May 24;277(21):19056-63. doi: 10.1074/jbc.M110960200. Epub 2002 Mar 12. J Biol Chem. 2002. PMID: 11891221 Free PMC article.

3

2-Chloro-N(6)-cyclopentyladenosine, adenosine A(1) receptor agonist, antagonizes the adenosine A(3) receptor.

Gao ZG, Jacobson KA. Gao ZG, et al. Eur J Pharmacol. 2002 May 17;443(1-3):39-42. doi: 10.1016/s0014-2999(02)01552-2. Eur J Pharmacol. 2002. PMID: 12044789 Free PMC article.

4

Selective allosteric enhancement of agonist binding and function at human A3 adenosine receptors by a series of imidazoquinoline derivatives.

Gao ZG, Kim SG, Soltysiak KA, Melman N, IJzerman AP, Jacobson KA. Gao ZG, et al. Mol Pharmacol. 2002 Jul;62(1):81-9. doi: 10.1124/mol.62.1.81. Mol Pharmacol. 2002. PMID: 12065758 Free PMC article.

5

Synthesis, biological properties, and molecular modeling investigation of the first potent, selective, and water-soluble human A(3) adenosine receptor antagonist.

Maconi A, Pastorin G, Da Ros T, Spalluto G, Gao ZG, Jacobson KA, Baraldi PG, Cacciari B, Varani K, Moro S, Borea PA. Maconi A, et al. Among authors: gao zg. J Med Chem. 2002 Aug 15;45(17):3579-82. doi: 10.1021/jm020974x. J Med Chem. 2002. PMID: 12166930 Free PMC article.

6

Structural determinants of A(3) adenosine receptor activation: nucleoside ligands at the agonist/antagonist boundary.

Gao ZG, Kim SK, Biadatti T, Chen W, Lee K, Barak D, Kim SG, Johnson CR, Jacobson KA. Gao ZG, et al. J Med Chem. 2002 Sep 26;45(20):4471-84. doi: 10.1021/jm020211+. J Med Chem. 2002. PMID: 12238926 Free PMC article.

7

Differential allosteric modulation by amiloride analogues of agonist and antagonist binding at A(1) and A(3) adenosine receptors.

Gao ZG, Melman N, Erdmann A, Kim SG, Müller CE, IJzerman AP, Jacobson KA. Gao ZG, et al. Biochem Pharmacol. 2003 Feb 15;65(4):525-34. doi: 10.1016/s0006-2952(02)01556-3. Biochem Pharmacol. 2003. PMID: 12566079 Free PMC article.

8

Design, synthesis and binding affinity of 3'-fluoro analogues of Cl-IB-MECA as adenosine A3 receptor ligands.

Lim MH, Kim HO, Moon HR, Lee SJ, Chun MW, Gao ZG, Melman N, Jacobson KA, Kim JH, Jeong LS. Lim MH, et al. Among authors: gao zg. Bioorg Med Chem Lett. 2003 Mar 10;13(5):817-20. doi: 10.1016/s0960-894x(03)00027-1. Bioorg Med Chem Lett. 2003. PMID: 12617898

9

Tumor necrosis factor alpha-induced apoptosis in astrocytes is prevented by the activation of P2Y6, but not P2Y4 nucleotide receptors.

Kim SG, Soltysiak KA, Gao ZG, Chang TS, Chung E, Jacobson KA. Kim SG, et al. Among authors: gao zg. Biochem Pharmacol. 2003 Mar 15;65(6):923-31. doi: 10.1016/s0006-2952(02)01614-3. Biochem Pharmacol. 2003. PMID: 12623123 Free PMC article.

10

Identification of essential residues involved in the allosteric modulation of the human A(3) adenosine receptor.

Gao ZG, Kim SK, Gross AS, Chen A, Blaustein JB, Jacobson KA. Gao ZG, et al. Mol Pharmacol. 2003 May;63(5):1021-31. doi: 10.1124/mol.63.5.1021. Mol Pharmacol. 2003. PMID: 12695530 Free PMC article.

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