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Ancestry-based differences in the immune phenotype are associated with lupus activity.
Slight-Webb S, Thomas K, Smith M, Wagner CA, Macwana S, Bylinska A, Donato M, Dvorak M, Chang SE, Kuo A, Cheung P, Kalesinskas L, Ganesan A, Dermadi D, Guthridge CJ, DeJager W, Wright C, Foecke MH, Merrill JT, Chakravarty E, Arriens C, Maecker HT, Khatri P, Utz PJ, James JA, Guthridge JM. Slight-Webb S, et al. Among authors: arriens c. JCI Insight. 2023 Aug 22;8(16):e169584. doi: 10.1172/jci.insight.169584. JCI Insight. 2023. PMID: 37606045 Free PMC article.
Autoantibody-positive healthy individuals with lower lupus risk display a unique immune endotype.
Slight-Webb S, Smith M, Bylinska A, Macwana S, Guthridge C, Lu R, Merrill JT, Chakravarty E, Arriens C, Munroe ME, Maecker HT, Utz PJ, Guthridge JM, James JA. Slight-Webb S, et al. Among authors: arriens c. J Allergy Clin Immunol. 2020 Dec;146(6):1419-1433. doi: 10.1016/j.jaci.2020.04.047. Epub 2020 May 22. J Allergy Clin Immunol. 2020. PMID: 32446964 Free PMC article. Clinical Trial.
Adults with systemic lupus exhibit distinct molecular phenotypes in a cross-sectional study.
Guthridge JM, Lu R, Tran LT, Arriens C, Aberle T, Kamp S, Munroe ME, Dominguez N, Gross T, DeJager W, Macwana SR, Bourn RL, Apel S, Thanou A, Chen H, Chakravarty EF, Merrill JT, James JA. Guthridge JM, et al. Among authors: arriens c. EClinicalMedicine. 2020 Mar 4;20:100291. doi: 10.1016/j.eclinm.2020.100291. eCollection 2020 Mar. EClinicalMedicine. 2020. PMID: 32154507 Free PMC article.
Serologic markers of Epstein-Barr virus reactivation are associated with increased disease activity, inflammation, and interferon pathway activation in patients with systemic lupus erythematosus.
Wood RA, Guthridge L, Thurmond E, Guthridge CJ, Kheir JM, Bourn RL, Wagner CA, Chen H, DeJager W, Macwana SR, Kamp S, Lu R, Arriens C, Chakravarty EF, Thanou A, Merrill JT, Guthridge JM, James JA. Wood RA, et al. Among authors: arriens c. J Transl Autoimmun. 2021 Aug 31;4:100117. doi: 10.1016/j.jtauto.2021.100117. eCollection 2021. J Transl Autoimmun. 2021. PMID: 35005588 Free PMC article.
A Flare Risk Index Informed by Select Immune Mediators in Systemic Lupus Erythematosus.
Munroe ME, Blankenship D, DeFreese D, Purushothaman M, DeJager W, Macwana S, Guthridge JM, Kamp S, Redinger N, Aberle T, Chakravarty EF, Arriens C, Li Y, Zeng H, McCarthy-Fruin KA, Osei-Onomahm SA, Thanarajasingam U, James JA, Jupe E. Munroe ME, et al. Among authors: arriens c. Arthritis Rheumatol. 2023 May;75(5):723-735. doi: 10.1002/art.42389. Epub 2023 Mar 6. Arthritis Rheumatol. 2023. PMID: 36245261 Free PMC article.
31 results