Smith MD - Search Results

1

Quantitative flow cytometric selection of tau conformational nanobodies specific for pathological aggregates.

Zupancic JM, Smith MD, Trzeciakiewicz H, Skinner ME, Ferris SP, Makowski EK, Lucas MJ, McArthur N, Kane RS, Paulson HL, Tessier PM. Zupancic JM, et al. Among authors: smith md. Front Immunol. 2023 Aug 9;14:1164080. doi: 10.3389/fimmu.2023.1164080. eCollection 2023. Front Immunol. 2023. PMID: 37622125 Free PMC article.

2

Physicochemical Rules for Identifying Monoclonal Antibodies with Drug-like Specificity.

Zhang Y, Wu L, Gupta P, Desai AA, Smith MD, Rabia LA, Ludwig SD, Tessier PM. Zhang Y, et al. Among authors: smith md. Mol Pharm. 2020 Jul 6;17(7):2555-2569. doi: 10.1021/acs.molpharmaceut.0c00257. Epub 2020 Jun 11. Mol Pharm. 2020. PMID: 32453957 Free PMC article.

3

Directed evolution methods for overcoming trade-offs between protein activity and stability.

Stimple SD, Smith MD, Tessier PM. Stimple SD, et al. Among authors: smith md. AIChE J. 2020 Mar;66(3):e16814. doi: 10.1002/aic.16814. Epub 2019 Oct 9. AIChE J. 2020. PMID: 32719568 Free PMC article.

4

Rational affinity maturation of anti-amyloid antibodies with high conformational and sequence specificity.

Desai AA, Smith MD, Zhang Y, Makowski EK, Gerson JE, Ionescu E, Starr CG, Zupancic JM, Moore SJ, Sutter AB, Ivanova MI, Murphy GG, Paulson HL, Tessier PM. Desai AA, et al. Among authors: smith md. J Biol Chem. 2021 Jan-Jun;296:100508. doi: 10.1016/j.jbc.2021.100508. Epub 2021 Mar 4. J Biol Chem. 2021. PMID: 33675750 Free PMC article.

5

Directed evolution of potent neutralizing nanobodies against SARS-CoV-2 using CDR-swapping mutagenesis.

Zupancic JM, Desai AA, Schardt JS, Pornnoppadol G, Makowski EK, Smith MD, Kennedy AA, Garcia de Mattos Barbosa M, Cascalho M, Lanigan TM, Tai AW, Tessier PM. Zupancic JM, et al. Among authors: smith md. Cell Chem Biol. 2021 Sep 16;28(9):1379-1388.e7. doi: 10.1016/j.chembiol.2021.05.019. Epub 2021 Jun 24. Cell Chem Biol. 2021. PMID: 34171229 Free PMC article.

6

Engineered Multivalent Nanobodies Potently and Broadly Neutralize SARS-CoV-2 Variants.

Zupancic JM, Schardt JS, Desai AA, Makowski EK, Smith MD, Pornnoppadol G, Garcia de Mattos Barbosa M, Cascalho M, Lanigan TM, Tessier PM. Zupancic JM, et al. Among authors: smith md. Adv Ther (Weinh). 2021 Aug;4(8):2100099. doi: 10.1002/adtp.202100099. Epub 2021 Aug 2. Adv Ther (Weinh). 2021. PMID: 34514086 Free PMC article.

7

Agonist antibody discovery: Experimental, computational, and rational engineering approaches.

Schardt JS, Jhajj HS, O'Meara RL, Lwo TS, Smith MD, Tessier PM. Schardt JS, et al. Among authors: smith md. Drug Discov Today. 2022 Jan;27(1):31-48. doi: 10.1016/j.drudis.2021.09.008. Epub 2021 Sep 24. Drug Discov Today. 2022. PMID: 34571277 Free PMC article. Review.

8

Discovery and characterization of high-affinity, potent SARS-CoV-2 neutralizing antibodies via single B cell screening.

Schardt JS, Pornnoppadol G, Desai AA, Park KS, Zupancic JM, Makowski EK, Smith MD, Chen H, Garcia de Mattos Barbosa M, Cascalho M, Lanigan TM, Moon JJ, Tessier PM. Schardt JS, et al. Among authors: smith md. Sci Rep. 2021 Oct 20;11(1):20738. doi: 10.1038/s41598-021-99401-x. Sci Rep. 2021. PMID: 34671080 Free PMC article.

9

Rapid and Quantitative In Vitro Evaluation of SARS-CoV-2 Neutralizing Antibodies and Nanobodies.

Wu W, Tan X, Zupancic J, Schardt JS, Desai AA, Smith MD, Zhang J, Xie L, Oo MK, Tessier PM, Fan X. Wu W, et al. Among authors: smith md. Anal Chem. 2022 Mar 15;94(10):4504-4512. doi: 10.1021/acs.analchem.2c00062. Epub 2022 Mar 3. Anal Chem. 2022. PMID: 35238533 Free PMC article.

10

Isolating Anti-amyloid Antibodies from Yeast-Displayed Libraries.

Desai AA, Zupancic JM, Smith MD, Tessier PM. Desai AA, et al. Among authors: smith md. Methods Mol Biol. 2022;2491:471-490. doi: 10.1007/978-1-0716-2285-8_22. Methods Mol Biol. 2022. PMID: 35482203 Free PMC article.

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