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Exposure of volunteers to microgravity by dry immersion bed over 21 days results in gene expression changes and adaptation of T cells.
Gallardo-Dodd CJ, Oertlin C, Record J, Galvani RG, Sommerauer C, Kuznetsov NV, Doukoumopoulos E, Ali L, Oliveira MMS, Seitz C, Percipalle M, Nikić T, Sadova AA, Shulgina SM, Shmarov VA, Kutko OV, Vlasova DD, Orlova KD, Rykova MP, Andersson J, Percipalle P, Kutter C, Ponomarev SA, Westerberg LS. Gallardo-Dodd CJ, et al. Among authors: oertlin c. Sci Adv. 2023 Aug 25;9(34):eadg1610. doi: 10.1126/sciadv.adg1610. Epub 2023 Aug 25. Sci Adv. 2023. PMID: 37624890 Free PMC article.
Adaptation to mitochondrial stress requires CHOP-directed tuning of ISR.
Kaspar S, Oertlin C, Szczepanowska K, Kukat A, Senft K, Lucas C, Brodesser S, Hatzoglou M, Larsson O, Topisirovic I, Trifunovic A. Kaspar S, et al. Among authors: oertlin c. Sci Adv. 2021 May 26;7(22):eabf0971. doi: 10.1126/sciadv.abf0971. Print 2021 May. Sci Adv. 2021. PMID: 34039602 Free PMC article.
eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma.
Chan K, Robert F, Oertlin C, Kapeller-Libermann D, Avizonis D, Gutierrez J, Handly-Santana A, Doubrovin M, Park J, Schoepfer C, Da Silva B, Yao M, Gorton F, Shi J, Thomas CJ, Brown LE, Porco JA Jr, Pollak M, Larsson O, Pelletier J, Chio IIC. Chan K, et al. Among authors: oertlin c. Nat Commun. 2019 Nov 13;10(1):5151. doi: 10.1038/s41467-019-13086-5. Nat Commun. 2019. PMID: 31723131 Free PMC article.
Polysome-profiling in small tissue samples.
Liang S, Bellato HM, Lorent J, Lupinacci FCS, Oertlin C, van Hoef V, Andrade VP, Roffé M, Masvidal L, Hajj GNM, Larsson O. Liang S, et al. Among authors: oertlin c. Nucleic Acids Res. 2018 Jan 9;46(1):e3. doi: 10.1093/nar/gkx940. Nucleic Acids Res. 2018. PMID: 29069469 Free PMC article.