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Human intestinal organoid models for celiac disease research.
Dotsenko V, Sioofy-Khojine AB, Hyöty H, Viiri K. Dotsenko V, et al. Among authors: viiri k. Methods Cell Biol. 2023;179:173-193. doi: 10.1016/bs.mcb.2023.01.008. Epub 2023 Feb 24. Methods Cell Biol. 2023. PMID: 37625874
Histological, immunohistochemical and mRNA gene expression responses in coeliac disease patients challenged with gluten using PAXgene fixed paraffin-embedded duodenal biopsies.
Taavela J, Viiri K, Popp A, Oittinen M, Dotsenko V, Peräaho M, Staff S, Sarin J, Leon F, Mäki M, Isola J. Taavela J, et al. Among authors: viiri k. BMC Gastroenterol. 2019 Nov 15;19(1):189. doi: 10.1186/s12876-019-1089-7. BMC Gastroenterol. 2019. PMID: 31730447 Free PMC article.
Genome-Wide Transcriptomic Analysis of Intestinal Mucosa in Celiac Disease Patients on a Gluten-Free Diet and Postgluten Challenge.
Dotsenko V, Oittinen M, Taavela J, Popp A, Peräaho M, Staff S, Sarin J, Leon F, Isola J, Mäki M, Viiri K. Dotsenko V, et al. Among authors: viiri k. Cell Mol Gastroenterol Hepatol. 2021;11(1):13-32. doi: 10.1016/j.jcmgh.2020.07.010. Epub 2020 Jul 31. Cell Mol Gastroenterol Hepatol. 2021. PMID: 32745639 Free PMC article. Clinical Trial.
The Oral Transglutaminase 2 Inhibitor ZED1227 Accumulates in the Villous Enterocytes in Celiac Disease Patients during Gluten Challenge and Drug Treatment.
Isola J, Mäki M, Hils M, Pasternack R, Viiri K, Dotsenko V, Montonen T, Zimmermann T, Mohrbacher R, Greinwald R, Schuppan D. Isola J, et al. Among authors: viiri k. Int J Mol Sci. 2023 Jun 28;24(13):10815. doi: 10.3390/ijms241310815. Int J Mol Sci. 2023. PMID: 37445994 Free PMC article. Clinical Trial.
Transcriptomic analysis of intestine following administration of a transglutaminase 2 inhibitor to prevent gluten-induced intestinal damage in celiac disease.
Dotsenko V, Tewes B, Hils M, Pasternack R, Isola J, Taavela J, Popp A, Sarin J, Huhtala H, Hiltunen P, Zimmermann T, Mohrbacher R, Greinwald R, Lundin KEA, Schuppan D, Mäki M, Viiri K; CEC-3 Investigators. Dotsenko V, et al. Among authors: viiri k. Nat Immunol. 2024 Jul;25(7):1218-1230. doi: 10.1038/s41590-024-01867-0. Epub 2024 Jun 24. Nat Immunol. 2024. PMID: 38914866 Free PMC article. Clinical Trial.
Polycomb Repressive Complex 2 Regulates Genes Necessary for Intestinal Microfold Cell (M Cell) Development.
George JJ, Oittinen M, Martin-Diaz L, Zapilko V, Iqbal S, Rintakangas T, Arrojo Martins FT, Niskanen H, Katajisto P, Kaikkonen MU, Viiri K. George JJ, et al. Among authors: viiri k. Cell Mol Gastroenterol Hepatol. 2021;12(3):873-889. doi: 10.1016/j.jcmgh.2021.05.014. Epub 2021 May 28. Cell Mol Gastroenterol Hepatol. 2021. PMID: 34058415 Free PMC article.
G2/M checkpoint regulation and apoptosis facilitate the nuclear egress of parvoviral capsids.
Mattola S, Mäntylä E, Aho V, Salminen S, Leclerc S, Oittinen M, Salokas K, Järvensivu J, Hakanen S, Ihalainen TO, Viiri K, Vihinen-Ranta M. Mattola S, et al. Among authors: viiri k. Front Cell Dev Biol. 2022 Dec 8;10:1070599. doi: 10.3389/fcell.2022.1070599. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 36568985 Free PMC article.
35 results