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DNA Methylation Signatures of Multiple Sclerosis Occur Independently of Known Genetic Risk and Are Primarily Attributed to B Cells and Monocytes.
Xavier A, Maltby VE, Ewing E, Campagna MP, Burnard SM, Tegner JN, Slee M, Butzkueven H, Kockum I, Kular L, Ausimmune/AusLong Investigators Group, Jokubaitis VG, Kilpatrick T, Alfredsson L, Jagodic M, Ponsonby AL, Taylor BV, Scott RJ, Lea RA, Lechner-Scott J. Xavier A, et al. Among authors: kular l. Int J Mol Sci. 2023 Aug 8;24(16):12576. doi: 10.3390/ijms241612576. Int J Mol Sci. 2023. PMID: 37628757 Free PMC article.
Epigenetic research in multiple sclerosis: progress, challenges, and opportunities.
Zheleznyakova GY, Piket E, Marabita F, Pahlevan Kakhki M, Ewing E, Ruhrmann S, Needhamsen M, Jagodic M, Kular L. Zheleznyakova GY, et al. Among authors: kular l. Physiol Genomics. 2017 Sep 1;49(9):447-461. doi: 10.1152/physiolgenomics.00060.2017. Epub 2017 Jul 28. Physiol Genomics. 2017. PMID: 28754822 Review.
Hypermethylation of MIR21 in CD4+ T cells from patients with relapsing-remitting multiple sclerosis associates with lower miRNA-21 levels and concomitant up-regulation of its target genes.
Ruhrmann S, Ewing E, Piket E, Kular L, Cetrulo Lorenzi JC, Fernandes SJ, Morikawa H, Aeinehband S, Sayols-Baixeras S, Aslibekyan S, Absher DM, Arnett DK, Tegner J, Gomez-Cabrero D, Piehl F, Jagodic M. Ruhrmann S, et al. Among authors: kular l. Mult Scler. 2018 Sep;24(10):1288-1300. doi: 10.1177/1352458517721356. Epub 2017 Aug 2. Mult Scler. 2018. PMID: 28766461 Free PMC article.
Genome-Wide Screen for MicroRNAs Reveals a Role for miR-203 in Melanoma Metastasis.
Lohcharoenkal W, Das Mahapatra K, Pasquali L, Crudden C, Kular L, Akkaya Ulum YZ, Zhang L, Xu Landén N, Girnita L, Jagodic M, Ståhle M, Sonkoly E, Pivarcsi A. Lohcharoenkal W, et al. Among authors: kular l. J Invest Dermatol. 2018 Apr;138(4):882-892. doi: 10.1016/j.jid.2017.09.049. Epub 2018 Feb 13. J Invest Dermatol. 2018. PMID: 29104160 Free article.
40 results