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213 results

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Page 1
Gene correction of human induced pluripotent stem cells repairs the cellular phenotype in pulmonary alveolar proteinosis.
Lachmann N, Happle C, Ackermann M, Lüttge D, Wetzke M, Merkert S, Hetzel M, Kensah G, Jara-Avaca M, Mucci A, Skuljec J, Dittrich AM, Pfaff N, Brennig S, Schambach A, Steinemann D, Göhring G, Cantz T, Martin U, Schwerk N, Hansen G, Moritz T. Lachmann N, et al. Am J Respir Crit Care Med. 2014 Jan 15;189(2):167-82. doi: 10.1164/rccm.201306-1012OC. Am J Respir Crit Care Med. 2014. PMID: 24279725
Promoter and lineage independent anti-silencing activity of the A2 ubiquitous chromatin opening element for optimized human pluripotent stem cell-based gene therapy.
Ackermann M, Lachmann N, Hartung S, Eggenschwiler R, Pfaff N, Happle C, Mucci A, Göhring G, Niemann H, Hansen G, Schambach A, Cantz T, Zweigerdt R, Moritz T. Ackermann M, et al. Among authors: lachmann n. Biomaterials. 2014 Feb;35(5):1531-42. doi: 10.1016/j.biomaterials.2013.11.024. Epub 2013 Nov 26. Biomaterials. 2014. PMID: 24290698
Pulmonary transplantation of macrophage progenitors as effective and long-lasting therapy for hereditary pulmonary alveolar proteinosis.
Happle C, Lachmann N, Škuljec J, Wetzke M, Ackermann M, Brennig S, Mucci A, Jirmo AC, Groos S, Mirenska A, Hennig C, Rodt T, Bankstahl JP, Schwerk N, Moritz T, Hansen G. Happle C, et al. Among authors: lachmann n. Sci Transl Med. 2014 Aug 20;6(250):250ra113. doi: 10.1126/scitranslmed.3009750. Sci Transl Med. 2014. PMID: 25143363
A minimal ubiquitous chromatin opening element (UCOE) effectively prevents silencing of juxtaposed heterologous promoters by epigenetic remodeling in multipotent and pluripotent stem cells.
Müller-Kuller U, Ackermann M, Kolodziej S, Brendel C, Fritsch J, Lachmann N, Kunkel H, Lausen J, Schambach A, Moritz T, Grez M. Müller-Kuller U, et al. Among authors: lachmann n. Nucleic Acids Res. 2015 Feb 18;43(3):1577-92. doi: 10.1093/nar/gkv019. Epub 2015 Jan 20. Nucleic Acids Res. 2015. PMID: 25605798 Free PMC article.
Large-scale hematopoietic differentiation of human induced pluripotent stem cells provides granulocytes or macrophages for cell replacement therapies.
Lachmann N, Ackermann M, Frenzel E, Liebhaber S, Brennig S, Happle C, Hoffmann D, Klimenkova O, Lüttge D, Buchegger T, Kühnel MP, Schambach A, Janciauskiene S, Figueiredo C, Hansen G, Skokowa J, Moritz T. Lachmann N, et al. Stem Cell Reports. 2015 Feb 10;4(2):282-96. doi: 10.1016/j.stemcr.2015.01.005. Stem Cell Reports. 2015. PMID: 25680479 Free PMC article.
Lost in translation: pluripotent stem cell-derived hematopoiesis.
Ackermann M, Liebhaber S, Klusmann JH, Lachmann N. Ackermann M, et al. Among authors: lachmann n. EMBO Mol Med. 2015 Nov;7(11):1388-402. doi: 10.15252/emmm.201505301. EMBO Mol Med. 2015. PMID: 26174486 Free PMC article. Review.
213 results