Mathijssen RHJ - Search Results

1

Survival of Patients With Cancer With DPYD Variant Alleles and Dose-Individualized Fluoropyrimidine Therapy-A Matched-Pair Analysis.

Knikman JE, Wilting TA, Lopez-Yurda M, Henricks LM, Lunenburg CATC, de Man FM, Meulendijks D, Nieboer P, Droogendijk HJ, Creemers GJ, Mandigers CMPW, Imholz ALT, Mathijssen RHJ, Portielje JEA, Valkenburg-van Iersel L, Vulink A, van der Poel MHW, Baars A, Swen JJ, Gelderblom H, Schellens JHM, Beijnen JH, Guchelaar HJ, Cats A. Knikman JE, et al. Among authors: mathijssen rhj. J Clin Oncol. 2023 Dec 10;41(35):5411-5421. doi: 10.1200/JCO.22.02780. Epub 2023 Aug 28. J Clin Oncol. 2023. PMID: 37639651

2

Pharmacogenetic pathway analysis for determination of sunitinib-induced toxicity.

van Erp NP, Eechoute K, van der Veldt AA, Haanen JB, Reyners AK, Mathijssen RH, Boven E, van der Straaten T, Baak-Pablo RF, Wessels JA, Guchelaar HJ, Gelderblom H. van Erp NP, et al. J Clin Oncol. 2009 Sep 10;27(26):4406-12. doi: 10.1200/JCO.2008.21.7679. Epub 2009 Aug 10. J Clin Oncol. 2009. PMID: 19667267

3

Influence of pharmacogenetic variability on the pharmacokinetics and toxicity of the aurora kinase inhibitor danusertib.

Steeghs N, Mathijssen RH, Wessels JA, de Graan AJ, van der Straaten T, Mariani M, Laffranchi B, Comis S, de Jonge MJ, Gelderblom H, Guchelaar HJ. Steeghs N, et al. Invest New Drugs. 2011 Oct;29(5):953-62. doi: 10.1007/s10637-010-9405-7. Epub 2010 Feb 25. Invest New Drugs. 2011. PMID: 20182906 Free PMC article. Clinical Trial.

4

Pharmacogenetics of tomorrow: the 1 + 1 = 3 principle.

Pander J, Wessels JA, Mathijssen RH, Gelderblom H, Guchelaar HJ. Pander J, et al. Pharmacogenomics. 2010 Jul;11(7):1011-7. doi: 10.2217/pgs.10.87. Pharmacogenomics. 2010. PMID: 20602619

5

Effects of methimazole on the elimination of irinotecan.

van der Bol JM, Visser TJ, Loos WJ, de Jong FA, Wiemer EA, van Aken MO, Planting AS, Schellens JH, Verweij J, Mathijssen RH. van der Bol JM, et al. Cancer Chemother Pharmacol. 2011 Jan;67(1):231-6. doi: 10.1007/s00280-010-1414-x. Epub 2010 Aug 1. Cancer Chemother Pharmacol. 2011. PMID: 20680278 Free PMC article.

6

Moving towards dose individualization of tyrosine kinase inhibitors.

Klümpen HJ, Samer CF, Mathijssen RH, Schellens JH, Gurney H. Klümpen HJ, et al. Cancer Treat Rev. 2011 Jun;37(4):251-60. doi: 10.1016/j.ctrv.2010.08.006. Epub 2010 Sep 15. Cancer Treat Rev. 2011. PMID: 20833478 Review.

7

Genetic polymorphisms associated with a prolonged progression-free survival in patients with metastatic renal cell cancer treated with sunitinib.

van der Veldt AA, Eechoute K, Gelderblom H, Gietema J, Guchelaar HJ, van Erp NP, van den Eertwegh AJ, Haanen JB, Mathijssen RH, Wessels JA. van der Veldt AA, et al. Clin Cancer Res. 2011 Feb 1;17(3):620-9. doi: 10.1158/1078-0432.CCR-10-1828. Epub 2010 Nov 19. Clin Cancer Res. 2011. PMID: 21097692

8

Dextromethorphan as a phenotyping test to predict endoxifen exposure in patients on tamoxifen treatment.

de Graan AJ, Teunissen SF, de Vos FY, Loos WJ, van Schaik RH, de Jongh FE, de Vos AI, van Alphen RJ, van der Holt B, Verweij J, Seynaeve C, Beijnen JH, Mathijssen RH. de Graan AJ, et al. J Clin Oncol. 2011 Aug 20;29(24):3240-6. doi: 10.1200/JCO.2010.32.9839. Epub 2011 Jul 18. J Clin Oncol. 2011. PMID: 21768449 Clinical Trial.

9

Association analysis of genetic polymorphisms in genes related to sunitinib pharmacokinetics, specifically clearance of sunitinib and SU12662.

Diekstra MH, Klümpen HJ, Lolkema MP, Yu H, Kloth JS, Gelderblom H, van Schaik RH, Gurney H, Swen JJ, Huitema AD, Steeghs N, Mathijssen RH. Diekstra MH, et al. Clin Pharmacol Ther. 2014 Jul;96(1):81-9. doi: 10.1038/clpt.2014.47. Epub 2014 Feb 24. Clin Pharmacol Ther. 2014. PMID: 24566734

10

Population pharmacokinetic modelling to assess the impact of CYP2D6 and CYP3A metabolic phenotypes on the pharmacokinetics of tamoxifen and endoxifen.

ter Heine R, Binkhorst L, de Graan AJ, de Bruijn P, Beijnen JH, Mathijssen RH, Huitema AD. ter Heine R, et al. Br J Clin Pharmacol. 2014 Sep;78(3):572-86. doi: 10.1111/bcp.12388. Br J Clin Pharmacol. 2014. PMID: 24697814 Free PMC article.

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