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881 results

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Page 1
Molecular Characterization of Endometrial Carcinomas in Black and White Patients Reveals Disparate Drivers with Therapeutic Implications.
Weigelt B, Marra A, Selenica P, Rios-Doria E, Momeni-Boroujeni A, Berger MF, Arora K, Nemirovsky D, Iasonos A, Chakravarty D, Abu-Rustum NR, Da Cruz Paula A, Dessources K, Ellenson LH, Liu YL, Aghajanian C, Brown CL. Weigelt B, et al. Among authors: arora k. Cancer Discov. 2023 Nov 1;13(11):2356-2369. doi: 10.1158/2159-8290.CD-23-0546. Cancer Discov. 2023. PMID: 37651310 Free PMC article.
Differences in Prostate Cancer Genomes by Self-reported Race: Contributions of Genetic Ancestry, Modifiable Cancer Risk Factors, and Clinical Factors.
Stopsack KH, Nandakumar S, Arora K, Nguyen B, Vasselman SE, Nweji B, McBride SM, Morris MJ, Rathkopf DE, Slovin SF, Danila DC, Autio KA, Scher HI, Mucci LA, Solit DB, Gönen M, Chen Y, Berger MF, Schultz N, Abida W, Kantoff PW. Stopsack KH, et al. Among authors: arora k. Clin Cancer Res. 2022 Jan 15;28(2):318-326. doi: 10.1158/1078-0432.CCR-21-2577. Epub 2021 Oct 19. Clin Cancer Res. 2022. PMID: 34667026 Free PMC article.
Diverse alterations associated with resistance to KRAS(G12C) inhibition.
Zhao Y, Murciano-Goroff YR, Xue JY, Ang A, Lucas J, Mai TT, Da Cruz Paula AF, Saiki AY, Mohn D, Achanta P, Sisk AE, Arora KS, Roy RS, Kim D, Li C, Lim LP, Li M, Bahr A, Loomis BR, de Stanchina E, Reis-Filho JS, Weigelt B, Berger M, Riely G, Arbour KC, Lipford JR, Li BT, Lito P. Zhao Y, et al. Nature. 2021 Nov;599(7886):679-683. doi: 10.1038/s41586-021-04065-2. Epub 2021 Nov 10. Nature. 2021. PMID: 34759319 Free PMC article.
Molecular and phenotypic profiling of colorectal cancer patients in West Africa reveals biological insights.
Alatise OI, Knapp GC, Sharma A, Chatila WK, Arowolo OA, Olasehinde O, Famurewa OC, Omisore AD, Komolafe AO, Olaofe OO, Katung AI, Ibikunle DE, Egberongbe AA, Olatoke SA, Agodirin SO, Adesiyun OA, Adeyeye A, Kolawole OA, Olakanmi AO, Arora K, Constable J, Shah R, Basunia A, Sylvester B, Wu C, Weiser MR, Seier K, Gonen M, Stadler ZK, Kemel Y, Vakiani E, Berger MF, Chan TA, Solit DB, Shia J, Sanchez-Vega F, Schultz N, Brennan M, Smith JJ, Kingham TP. Alatise OI, et al. Among authors: arora k. Nat Commun. 2021 Nov 24;12(1):6821. doi: 10.1038/s41467-021-27106-w. Nat Commun. 2021. PMID: 34819518 Free PMC article.
Disparities in cancer genetics care by race/ethnicity among pan-cancer patients with pathogenic germline variants.
Liu YL, Maio A, Kemel Y, Salo-Mullen EE, Sheehan M, Tejada PR, Trottier M, Arnold AG, Fleischut MH, Latham A, Carlo MI, Murciano-Goroff YR, Walsh MF, Mandelker D, Mehta N, Bandlamudi C, Arora K, Zehir A, Berger MF, Solit DB, Aghajanian C, Diaz LA Jr, Robson ME, Brown CL, Offit K, Hamilton JG, Stadler ZK. Liu YL, et al. Among authors: arora k. Cancer. 2022 Nov 1;128(21):3870-3879. doi: 10.1002/cncr.34434. Epub 2022 Aug 30. Cancer. 2022. PMID: 36041233 Free PMC article.
Genetic Ancestry Correlates with Somatic Differences in a Real-World Clinical Cancer Sequencing Cohort.
Arora K, Tran TN, Kemel Y, Mehine M, Liu YL, Nandakumar S, Smith SA, Brannon AR, Ostrovnaya I, Stopsack KH, Razavi P, Safonov A, Rizvi HA, Hellmann MD, Vijai J, Reynolds TC, Fagin JA, Carrot-Zhang J, Offit K, Solit DB, Ladanyi M, Schultz N, Zehir A, Brown CL, Stadler ZK, Chakravarty D, Bandlamudi C, Berger MF. Arora K, et al. Cancer Discov. 2022 Nov 2;12(11):2552-2565. doi: 10.1158/2159-8290.CD-22-0312. Cancer Discov. 2022. PMID: 36048199 Free PMC article.
Ancestry-driven recalibration of tumor mutational burden and disparate clinical outcomes in response to immune checkpoint inhibitors.
Nassar AH, Adib E, Abou Alaiwi S, El Zarif T, Groha S, Akl EW, Nuzzo PV, Mouhieddine TH, Perea-Chamblee T, Taraszka K, El-Khoury H, Labban M, Fong C, Arora KS, Labaki C, Xu W, Sonpavde G, Haddad RI, Mouw KW, Giannakis M, Hodi FS, Zaitlen N, Schoenfeld AJ, Schultz N, Berger MF, MacConaill LE, Ananda G, Kwiatkowski DJ, Choueiri TK, Schrag D, Carrot-Zhang J, Gusev A. Nassar AH, et al. Among authors: arora ks. Cancer Cell. 2022 Oct 10;40(10):1161-1172.e5. doi: 10.1016/j.ccell.2022.08.022. Epub 2022 Sep 29. Cancer Cell. 2022. PMID: 36179682 Free PMC article.
Germline Pathogenic Variants and Genetic Counseling by Ancestry in Patients With Epithelial Ovarian Cancer.
Sia TY, Maio A, Kemel YM, Arora KS, Gordhandas SB, Kahn RM, Salo-Mullen EE, Sheehan MA, Tejada PR, Bandlamudi C, Zhou Q, Iasonos A, Grisham RN, O'Cearbhaill RE, Tew WP, Long Roche K, Zivanovic O, Sonoda Y, Gardner GJ, Chi DS, Latham AJ, Carlo MI, Murciano-Goroff YR, Will M, Walsh MF, Robson ME, Mandelker DL, Berger MF, Abu-Rustum NR, Brown CL, Offit K, Hamilton JG, Aghajanian C, Weigelt B, Stadler ZK, Liu YL. Sia TY, et al. Among authors: arora ks. JCO Precis Oncol. 2023 Sep;7:e2300137. doi: 10.1200/PO.23.00137. JCO Precis Oncol. 2023. PMID: 37738546 Free PMC article.
Genomic ancestry in kidney cancer: Correlations with clinical and molecular features.
Kotecha RR, Knezevic A, Arora K, Bandlamudi C, Kuo F, Carlo MI, Fitzgerald KN, Feldman DR, Shah NJ, Reznik E, Hakimi AA, Carrot-Zhang J, Mandelker D, Berger M, Lee CH, Motzer RJ, Voss MH. Kotecha RR, et al. Among authors: arora k. Cancer. 2024 Mar 1;130(5):692-701. doi: 10.1002/cncr.35074. Epub 2023 Oct 21. Cancer. 2024. PMID: 37864521 Free PMC article.
Pathogenic germline variants in patients with endometrial cancer of diverse ancestry.
Liu YL, Gordhandas S, Arora K, Rios-Doria E, Cadoo KA, Catchings A, Maio A, Kemel Y, Sheehan M, Salo-Mullen E, Zhou Q, Iasonos A, Carrot-Zhang J, Manning-Geist B, Sia TY, Selenica P, Vanderbilt C, Misyura M, Latham A, Bandlamudi C, Berger MF, Hamilton JG, Makker V, Abu-Rustum NR, Ellenson LH, Offit K, Mandelker DL, Stadler Z, Weigelt B, Aghajanian C, Brown C. Liu YL, et al. Among authors: arora k. Cancer. 2024 Feb 15;130(4):576-587. doi: 10.1002/cncr.35071. Epub 2023 Oct 27. Cancer. 2024. PMID: 37886874
881 results