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Page 1
Biomarkers of aging for the identification and evaluation of longevity interventions.
Moqri M, Herzog C, Poganik JR; Biomarkers of Aging Consortium; Justice J, Belsky DW, Higgins-Chen A, Moskalev A, Fuellen G, Cohen AA, Bautmans I, Widschwendter M, Ding J, Fleming A, Mannick J, Han JJ, Zhavoronkov A, Barzilai N, Kaeberlein M, Cummings S, Kennedy BK, Ferrucci L, Horvath S, Verdin E, Maier AB, Snyder MP, Sebastiano V, Gladyshev VN. Moqri M, et al. Among authors: poganik jr. Cell. 2023 Aug 31;186(18):3758-3775. doi: 10.1016/j.cell.2023.08.003. Cell. 2023. PMID: 37657418 Free PMC article. Review.
Biological age is increased by stress and restored upon recovery.
Poganik JR, Zhang B, Baht GS, Tyshkovskiy A, Deik A, Kerepesi C, Yim SH, Lu AT, Haghani A, Gong T, Hedman AM, Andolf E, Pershagen G, Almqvist C, Clish CB, Horvath S, White JP, Gladyshev VN. Poganik JR, et al. Cell Metab. 2023 May 2;35(5):807-820.e5. doi: 10.1016/j.cmet.2023.03.015. Epub 2023 Apr 21. Cell Metab. 2023. PMID: 37086720 Free PMC article.
MethylGPT: a foundation model for the DNA methylome.
Ying K, Song J, Cui H, Zhang Y, Li S, Chen X, Liu H, Eames A, McCartney DL, Marioni RE, Poganik JR, Moqri M, Wang B, Gladyshev VN. Ying K, et al. Among authors: poganik jr. bioRxiv [Preprint]. 2024 Nov 4:2024.10.30.621013. doi: 10.1101/2024.10.30.621013. bioRxiv. 2024. PMID: 39574641 Free PMC article. Preprint.
An Open Competition for Biomarkers of Aging.
Ying K, Paulson S, Reinhard J, de Lima Camillo LP, Träuble J, Jokiel S; Biomarkers of Aging Consortium; Gobel D, Herzog C, Poganik JR, Moqri M, Gladyshev VN. Ying K, et al. Among authors: poganik jr. bioRxiv [Preprint]. 2024 Nov 3:2024.10.29.620782. doi: 10.1101/2024.10.29.620782. bioRxiv. 2024. PMID: 39554132 Free PMC article. Preprint.
High-dimensional Ageome Representations of Biological Aging across Functional Modules.
Ying K, Tyshkovskiy A, Chen Q, Latorre-Crespo E, Zhang B, Liu H, Matei-Dediu B, Poganik JR, Moqri M, Kirschne K, Lasky-Su J, Gladyshev VN. Ying K, et al. Among authors: poganik jr. bioRxiv [Preprint]. 2024 Sep 21:2024.09.17.613599. doi: 10.1101/2024.09.17.613599. bioRxiv. 2024. PMID: 39345525 Free PMC article. Preprint.
Challenges and recommendations for the translation of biomarkers of aging.
Biomarkers of Aging Consortium; Herzog CMS, Goeminne LJE, Poganik JR, Barzilai N, Belsky DW, Betts-LaCroix J, Chen BH, Chen M, Cohen AA, Cummings SR, Fedichev PO, Ferrucci L, Fleming A, Fortney K, Furman D, Gorbunova V, Higgins-Chen A, Hood L, Horvath S, Justice JN, Kiel DP, Kuchel GA, Lasky-Su J, LeBrasseur NK, Maier AB, Schilling B, Sebastiano V, Slagboom PE, Snyder MP, Verdin E, Widschwendter M, Zhavoronkov A, Moqri M, Gladyshev VN. Biomarkers of Aging Consortium, et al. Among authors: poganik jr. Nat Aging. 2024 Oct;4(10):1372-1383. doi: 10.1038/s43587-024-00683-3. Epub 2024 Sep 16. Nat Aging. 2024. PMID: 39285015 Review.
Validation of biomarkers of aging.
Moqri M, Herzog C, Poganik JR, Ying K, Justice JN, Belsky DW, Higgins-Chen AT, Chen BH, Cohen AA, Fuellen G, Hägg S, Marioni RE, Widschwendter M, Fortney K, Fedichev PO, Zhavoronkov A, Barzilai N, Lasky-Su J, Kiel DP, Kennedy BK, Cummings S, Slagboom PE, Verdin E, Maier AB, Sebastiano V, Snyder MP, Gladyshev VN, Horvath S, Ferrucci L. Moqri M, et al. Among authors: poganik jr. Nat Med. 2024 Feb;30(2):360-372. doi: 10.1038/s41591-023-02784-9. Epub 2024 Feb 14. Nat Med. 2024. PMID: 38355974 Free PMC article. Review.
TIME-seq reduces time and cost of DNA methylation measurement for epigenetic clock construction.
Griffin PT, Kane AE, Trapp A, Li J, Arnold M, Poganik JR, Conway RJ, McNamara MS, Meer MV, Hoffman N, Amorim JA, Tian X, MacArthur MR, Mitchell SJ, Mueller AL, Carmody C, Vera DL, Kerepesi C, Ying K, Noren Hooten N, Mitchell JR, Evans MK, Gladyshev VN, Sinclair DA. Griffin PT, et al. Among authors: poganik jr. Nat Aging. 2024 Feb;4(2):261-274. doi: 10.1038/s43587-023-00555-2. Epub 2024 Jan 10. Nat Aging. 2024. PMID: 38200273 Free PMC article.
We need to shift the focus of aging research to aging itself.
Poganik JR, Gladyshev VN. Poganik JR, et al. Proc Natl Acad Sci U S A. 2023 Sep 12;120(37):e2307449120. doi: 10.1073/pnas.2307449120. Epub 2023 Sep 8. Proc Natl Acad Sci U S A. 2023. PMID: 37682890 Free PMC article. No abstract available.
Author Correction: Universal DNA methylation age across mammalian tissues.
Lu AT, Fei Z, Haghani A, Robeck TR, Zoller JA, Li CZ, Lowe R, Yan Q, Zhang J, Vu H, Ablaeva J, Acosta-Rodriguez VA, Adams DM, Almunia J, Aloysius A, Ardehali R, Arneson A, Baker CS, Banks G, Belov K, Bennett NC, Black P, Blumstein DT, Bors EK, Breeze CE, Brooke RT, Brown JL, Carter GG, Caulton A, Cavin JM, Chakrabarti L, Chatzistamou I, Chen H, Cheng K, Chiavellini P, Choi OW, Clarke SM, Cooper LN, Cossette ML, Day J, DeYoung J, DiRocco S, Dold C, Ehmke EE, Emmons CK, Emmrich S, Erbay E, Erlacher-Reid C, Faulkes CG, Ferguson SH, Finno CJ, Flower JE, Gaillard JM, Garde E, Gerber L, Gladyshev VN, Gorbunova V, Goya RG, Grant MJ, Green CB, Hales EN, Hanson MB, Hart DW, Haulena M, Herrick K, Hogan AN, Hogg CJ, Hore TA, Huang T, Izpisua Belmonte JC, Jasinska AJ, Jones G, Jourdain E, Kashpur O, Katcher H, Katsumata E, Kaza V, Kiaris H, Kobor MS, Kordowitzki P, Koski WR, Krützen M, Kwon SB, Larison B, Lee SG, Lehmann M, Lemaitre JF, Levine AJ, Li C, Li X, Lim AR, Lin DTS, Lindemann DM, Little TJ, Macoretta N, Maddox D, Matkin CO, Mattison JA, McClure M, Mergl J, Meudt JJ, Montano GA, Mozhui K, Munshi-South J, Naderi A, Nagy M, Narayan P, Nathanielsz PW, Nguyen NB, Niehrs C, O'Brien JK, O'… See abstract for full author list ➔ Lu AT, et al. Among authors: poganik jr. Nat Aging. 2023 Nov;3(11):1462. doi: 10.1038/s43587-023-00499-7. Nat Aging. 2023. PMID: 37674040 Free PMC article. No abstract available.
29 results