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248 results

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A lentiviral vector B cell gene therapy platform for the delivery of the anti-HIV-1 eCD4-Ig-knob-in-hole-reversed immunoadhesin.
Vamva E, Ozog S, Leaman DP, Yu-Hong Cheng R, Irons NJ, Ott A, Stoffers C, Khan I, Goebrecht GKE, Gardner MR, Farzan M, Rawlings DJ, Zwick MB, James RG, Torbett BE. Vamva E, et al. Among authors: rawlings dj. Mol Ther Methods Clin Dev. 2023 Feb 11;28:366-384. doi: 10.1016/j.omtm.2023.02.004. eCollection 2023 Mar 9. Mol Ther Methods Clin Dev. 2023. PMID: 36879849 Free PMC article.
A chemically inducible IL-2 receptor signaling complex allows for effective in vitro and in vivo selection of engineered CD4+ T cells.
Cook PJ, Yang SJ, Uenishi GI, Grimm A, West SE, Wang LJ, Jacobs C, Repele A, Drow T, Boukhris A, Dahl NP, Sommer K, Scharenberg AM, Rawlings DJ. Cook PJ, et al. Among authors: rawlings dj. Mol Ther. 2023 Aug 2;31(8):2472-2488. doi: 10.1016/j.ymthe.2023.04.021. Epub 2023 May 4. Mol Ther. 2023. PMID: 37147803 Free PMC article.
Efficient and sustained FOXP3 locus editing in hematopoietic stem cells as a therapeutic approach for IPEX syndrome.
Singh S, Pugliano CM, Honaker Y, Laird A, DeGottardi MQ, Lopez E, Lachkar S, Stoffers C, Sommer K, Khan IF, Rawlings DJ. Singh S, et al. Among authors: rawlings dj. Mol Ther Methods Clin Dev. 2023 Dec 26;32(1):101183. doi: 10.1016/j.omtm.2023.101183. eCollection 2024 Mar 14. Mol Ther Methods Clin Dev. 2023. PMID: 38282895 Free PMC article.
GNTI-122: an autologous antigen-specific engineered Treg cell therapy for type 1 diabetes.
Uenishi GI, Repic M, Yam JY, Landuyt A, Saikumar-Lakshmi P, Guo T, Zarin P, Sassone-Corsi M, Chicoine A, Kellogg H, Hunt M, Drow T, Tewari R, Cook PJ, Yang SJ, Cerosaletti K, Schweinoch D, Guiastrennec B, James E, Patel C, Chen TF, Buckner JH, Rawlings DJ, Wickham TJ, Mueller KT. Uenishi GI, et al. Among authors: rawlings dj. JCI Insight. 2024 Feb 8;9(6):e171844. doi: 10.1172/jci.insight.171844. JCI Insight. 2024. PMID: 38516892 Free PMC article.
Identification of a novel PDC-E2 epitope in primary biliary cholangitis: Application for engineered Treg therapy.
Tewari R, Yang SJ, McClain ED, Hu A, Mortensen E, DeSchmidt A, Chen J, Kancharla A, Singh AK, James EA, Burman BE, Siddique A, Rawlings DJ, Patel C, Cerosaletti K, Buckner JH. Tewari R, et al. Among authors: rawlings dj. J Autoimmun. 2024 Oct 29;149:103327. doi: 10.1016/j.jaut.2024.103327. Online ahead of print. J Autoimmun. 2024. PMID: 39476446
248 results