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2,253 results

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Page 1
Discovery of a selective and biologically active low-molecular weight antagonist of human interleukin-1β.
Hommel U, Hurth K, Rondeau JM, Vulpetti A, Ostermeier D, Boettcher A, Brady JP, Hediger M, Lehmann S, Koch E, Blechschmidt A, Yamamoto R, Tundo Dottorello V, Haenni-Holzinger S, Kaiser C, Lehr P, Lingel A, Mureddu L, Schleberger C, Blank J, Ramage P, Freuler F, Eder J, Bornancin F. Hommel U, et al. Among authors: yamamoto r. Nat Commun. 2023 Sep 7;14(1):5497. doi: 10.1038/s41467-023-41190-0. Nat Commun. 2023. PMID: 37679328 Free PMC article.
Ligandability Assessment of IL-1β by Integrated Hit Identification Approaches.
Vulpetti A, Rondeau JM, Bellance MH, Blank J, Boesch R, Boettcher A, Bornancin F, Buhr S, Connor LE, Dumelin CE, Esser O, Hediger M, Hintermann S, Hommel U, Koch E, Lapointe G, Leder L, Lehmann S, Lehr P, Meier P, Muller L, Ostermeier D, Ramage P, Schiebel-Haddad S, Smith AB, Stojanovic A, Velcicky J, Yamamoto R, Hurth K. Vulpetti A, et al. Among authors: yamamoto r. J Med Chem. 2024 May 23;67(10):8141-8160. doi: 10.1021/acs.jmedchem.4c00240. Epub 2024 May 10. J Med Chem. 2024. PMID: 38728572
A selective metabotropic glutamate receptor 7 agonist: activation of receptor signaling via an allosteric site modulates stress parameters in vivo.
Mitsukawa K, Yamamoto R, Ofner S, Nozulak J, Pescott O, Lukic S, Stoehr N, Mombereau C, Kuhn R, McAllister KH, van der Putten H, Cryan JF, Flor PJ. Mitsukawa K, et al. Among authors: yamamoto r. Proc Natl Acad Sci U S A. 2005 Dec 20;102(51):18712-7. doi: 10.1073/pnas.0508063102. Epub 2005 Dec 9. Proc Natl Acad Sci U S A. 2005. PMID: 16339898 Free PMC article.
mGluR7 facilitates extinction of aversive memories and controls amygdala plasticity.
Fendt M, Schmid S, Thakker DR, Jacobson LH, Yamamoto R, Mitsukawa K, Maier R, Natt F, Hüsken D, Kelly PH, McAllister KH, Hoyer D, van der Putten H, Cryan JF, Flor PJ. Fendt M, et al. Among authors: yamamoto r. Mol Psychiatry. 2008 Oct;13(10):970-9. doi: 10.1038/sj.mp.4002073. Epub 2007 Aug 21. Mol Psychiatry. 2008. PMID: 17712315
Oxytocin Receptor Polymorphism Is Associated With Sleep Apnea Symptoms.
Goto H, Yamamoto Y, Tsujiguchi H, Sato T, Yamamoto R, Takeshita Y, Nakano Y, Kannon T, Hosomichi K, Suzuki K, Nakamura M, Kambayashi Y, Zhao J, Asai A, Katano K, Ogawa A, Fukushima S, Shibata A, Suzuki F, Tsuboi H, Hara A, Kometani M, Karashima S, Yoneda T, Tajima A, Nakamura H, Takamura T. Goto H, et al. Among authors: yamamoto r. J Endocr Soc. 2024 Nov 26;9(1):bvae198. doi: 10.1210/jendso/bvae198. eCollection 2024 Nov 26. J Endocr Soc. 2024. PMID: 39606181 Free PMC article.
Effects of canagliflozin on brain natriuretic peptide levels in patients with type 2 diabetes on peritoneal dialysis in Japan: protocol for a multicentre, prospective, randomised controlled trial (CARD-PD trial).
Matsuoka N, Nakazawa D, Nishio S, Cho KY, Maoka T, Kaneshima N, Yamamoto R, Yamamoto J, Shimamoto M, Makita M, Iriuda S, Igarashi K, Ito Y, Kato A, Yoshikawa J, Kudo T, Nagashima T, Ito YM, Atsumi T. Matsuoka N, et al. Among authors: yamamoto r. BMJ Open. 2024 Nov 25;14(11):e084846. doi: 10.1136/bmjopen-2024-084846. BMJ Open. 2024. PMID: 39592158 Free PMC article. Clinical Trial.
2,253 results