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Identification of Brain-Penetrant ATP-Competitive mTOR Inhibitors for CNS Syndromes.
Bonazzi S, Gray A, Thomsen NM, Biag J, Labbe-Giguere N, Keaney EP, Malik HA, Sun Y, Nunez J, Karki RG, Knapp M, Elling R, Fuller J, Pardee G, Craig L, Capre K, Salas S, Gorde A, Liang G, Lubicka D, McTighe SM, Goold C, Liu S, Deng L, Hong J, Fekete A, Stadelmann P, Frieauff W, Elhajouji A, Bauer D, Lerchner A, Radetich B, Furet P, Piizzi G, Burdette D, Wilson CJ, Peukert S, Hamann LG, Murphy LO, Curtis D. Bonazzi S, et al. Among authors: piizzi g. J Med Chem. 2023 Jul 13;66(13):9095-9119. doi: 10.1021/acs.jmedchem.3c00705. Epub 2023 Jul 3. J Med Chem. 2023. PMID: 37399505
Detection of cell-cell interactions via photocatalytic cell tagging.
Oslund RC, Reyes-Robles T, White CH, Tomlinson JH, Crotty KA, Bowman EP, Chang D, Peterson VM, Li L, Frutos S, Vila-Perelló M, Vlerick D, Cromie K, Perlman DH, Ingale S, Hara SDO, Roberts LR, Piizzi G, Hett EC, Hazuda DJ, Fadeyi OO. Oslund RC, et al. Among authors: piizzi g. Nat Chem Biol. 2022 Aug;18(8):850-858. doi: 10.1038/s41589-022-01044-0. Epub 2022 Jun 2. Nat Chem Biol. 2022. PMID: 35654846
High-Throughput Screen for Inhibitors of Klebsiella pneumoniae Virulence Using a Tetrahymena pyriformis Co-Culture Surrogate Host Model.
Woods AL, Parker D, Glick MM, Peng Y, Lenoir F, Mulligan E, Yu V, Piizzi G, Lister T, Lilly MD, Dzink-Fox J, Jansen JM, Ryder NS, Dean CR, Smith TM. Woods AL, et al. Among authors: piizzi g. ACS Omega. 2022 Feb 1;7(6):5401-5414. doi: 10.1021/acsomega.1c06633. eCollection 2022 Feb 15. ACS Omega. 2022. PMID: 35187355 Free PMC article.
Cellular Stress Upregulates Indole Signaling Metabolites in Escherichia coli.
Kim CS, Li JH, Barco B, Park HB, Gatsios A, Damania A, Wang R, Wyche TP, Piizzi G, Clay NK, Crawford JM. Kim CS, et al. Among authors: piizzi g. Cell Chem Biol. 2020 Jun 18;27(6):698-707.e7. doi: 10.1016/j.chembiol.2020.03.003. Epub 2020 Apr 2. Cell Chem Biol. 2020. PMID: 32243812 Free PMC article.
25 results