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445 results

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Page 1
Catastrophic ATP loss underlies a metabolic combination therapy tailored for MYCN-amplified neuroblastoma.
Dalton KM, Lochmann TL, Floros KV, Calbert ML, Kurupi R, Stein GT, McClanaghan J, Murchie E, Egan RK, Greninger P, Dozmorov M, Ramamoorthy S, Puchalapalli M, Hu B, Shock L, Koblinski J, Glod J, Boikos SA, Benes CH, Faber AC. Dalton KM, et al. Proc Natl Acad Sci U S A. 2021 Mar 30;118(13):e2009620118. doi: 10.1073/pnas.2009620118. Proc Natl Acad Sci U S A. 2021. PMID: 33762304 Free PMC article.
Venetoclax-based Rational Combinations are Effective in Models of MYCN-amplified Neuroblastoma.
Dalton KM, Krytska K, Lochmann TL, Sano R, Casey C, D'Aulerio A, Khan QA, Crowther GS, Coon C, Cai J, Jacob S, Kurupi R, Hu B, Dozmorov M, Greninger P, Souers AJ, Benes CH, Mossé YP, Faber AC. Dalton KM, et al. Mol Cancer Ther. 2021 Aug;20(8):1400-1411. doi: 10.1158/1535-7163.MCT-20-0710. Epub 2021 Jun 4. Mol Cancer Ther. 2021. PMID: 34088831 Free PMC article.
High-risk neuroblastoma with NF1 loss of function is targetable using SHP2 inhibition.
Cai J, Jacob S, Kurupi R, Dalton KM, Coon C, Greninger P, Egan RK, Stein GT, Murchie E, McClanaghan J, Adachi Y, Hirade K, Dozmorov M, Glod J, Boikos SA, Ebi H, Hao H, Caponigro G, Benes CH, Faber AC. Cai J, et al. Among authors: dalton km. Cell Rep. 2022 Jul 26;40(4):111095. doi: 10.1016/j.celrep.2022.111095. Cell Rep. 2022. PMID: 35905710 Free PMC article.
Pharmacologic Inhibition of SHP2 Blocks Both PI3K and MEK Signaling in Low-epiregulin HNSCC via GAB1.
Kurupi R, Floros KV, Jacob S, Chawla AT, Cai J, Hu B, Puchalapalli M, Coon CM, Khatri R, Crowther GS, Egan RK, Murchie E, Greninger P, Dalton KM, Ghotra MS, Boikos SA, Koblinski JE, Harada H, Sun Y, Morgan IM, Basu D, Dozmorov MG, Benes CH, Faber AC. Kurupi R, et al. Among authors: dalton km. Cancer Res Commun. 2022 Sep;2(9):1061-1074. doi: 10.1158/2767-9764.crc-21-0137. Epub 2022 Sep 26. Cancer Res Commun. 2022. PMID: 36506869 Free PMC article.
Targeting of SUMOylation leads to cBAF complex stabilization and disruption of the SS18::SSX transcriptome in Synovial Sarcoma.
Floros KV, Fairchild CK, Li J, Zhang K, Roberts JL, Kurupi R, Hu B, Kraskauskiene V, Hosseini N, Shen S, Inge MM, Smith-Fry K, Li L, Sotiriou A, Dalton KM, Jose A, Abdelfadiel EI, Xing Y, Hill RD, Slaughter JM, Shende M, Lorenz MR, Hinojosa MR, Belvin BR, Lai Z, Boikos SA, Stamatouli AM, Lewis JP, Manjili MH, Valerie K, Li R, Banito A, Poklepovic A, Koblinski JE, Siggers T, Dozmorov MG, Jones KB, Radhakrishnan SK, Faber AC. Floros KV, et al. Among authors: dalton km. bioRxiv [Preprint]. 2024 Apr 27:2024.04.25.591023. doi: 10.1101/2024.04.25.591023. bioRxiv. 2024. PMID: 38712286 Free PMC article. Preprint.
Targeting of SUMOylation leads to cBAF complex stabilization and disruption of the SS18::SSX transcriptome in Synovial Sarcoma.
Floros KV, Fairchild CK Jr, Li J, Zhang K, Roberts JL, Kurupi R, Hu B, Kraskauskiene V, Hosseini N, Shen S, Inge MM, Smith-Fry K, Li L, Sotiriou A, Dalton KM, Jose A, Abdelfadiel EI, Xing Y, Hill RD, Slaughter JM, Shende M, Lorenz MR, Hinojosa MR, Belvin BR, Lai Z, Boikos SA, Stamatouli AM, Lewis JP, Manjili MH, Valerie K, Li R, Banito A, Poklepovic A, Koblinski JE, Siggers T, Dozmorov MG, Jones KB, Radhakrishnan SK, Faber AC. Floros KV, et al. Among authors: dalton km. Res Sq [Preprint]. 2024 Jun 6:rs.3.rs-4362092. doi: 10.21203/rs.3.rs-4362092/v1. Res Sq. 2024. PMID: 38883782 Free PMC article. Preprint.
Exploring Sex, Gender, and Gender-Related Sociocultural Factors in Clinical Decision-Making for Older Adults Using a Prescribing Cascade Vignette: A Transnational Qualitative Study.
Kthupi A, Rochon PA, Santini S, Paoletti L, Mason R, McCarthy LM, Carrieri B, Dalton K, Li J, Sivayoganathan K, Borhani P, Sternberg SA, Zwas DR, Savage RD; iKASCADE Team. Kthupi A, et al. Among authors: dalton k. Drugs Aging. 2024 Nov 27. doi: 10.1007/s40266-024-01158-1. Online ahead of print. Drugs Aging. 2024. PMID: 39602002
TET2 regulates early and late transitions in exhausted CD8+ T cell differentiation and limits CAR T cell function.
Dimitri AJ, Baxter AE, Chen GM, Hopkins CR, Rouin GT, Huang H, Kong W, Holliday CH, Wiebking V, Bartoszek R, Drury S, Dalton K, Koucky OM, Chen Z, Giles JR, Dils AT, Jung IY, O'Connor R, Collins S, Everett JK, Amses K, Sherrill-Mix S, Chandra A, Goldman N, Vahedi G, Jadlowsky JK, Young RM, Melenhorst JJ, Maude SL, Levine BL, Frey NV, Berger SL, Grupp SA, Porter DL, Herbst F, Porteus MH, Carty SA, Bushman FD, Weber EW, Wherry EJ, Jordan MS, Fraietta JA. Dimitri AJ, et al. Among authors: dalton k. Sci Adv. 2024 Nov 15;10(46):eadp9371. doi: 10.1126/sciadv.adp9371. Epub 2024 Nov 13. Sci Adv. 2024. PMID: 39536093 Free PMC article.
Para athlete concussion care following the Amsterdam 2022 International Consensus Statement on Concussion in Sport: an urgent need for inclusivity within concussion research.
Weiler R, Dalton K, Guenther A, Mitchell K, Van de Vliet P, Babul S, Blauwet C, Clarke D, Dea J, Derman W, Emery C, Fagher K, Gouttebarge V, Haider MN, Hunt T, Lee K, Lexell J, Moran RN, Pilon F, Prince F, Runciman P, Smetana R, Verhagen E, Webborn N, Ahmed OH. Weiler R, et al. Among authors: dalton k. Br J Sports Med. 2024 Nov 7:bjsports-2024-108871. doi: 10.1136/bjsports-2024-108871. Online ahead of print. Br J Sports Med. 2024. PMID: 39510817 No abstract available.
445 results