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Page 1
RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells.
Krishnan R, Lapierre M, Gautreau B, Nixon KCJ, El Ghamrasni S, Patel PS, Hao J, Yerlici VT, Guturi KKN, St-Germain J, Mateo F, Saad A, Algouneh A, Earnshaw R, Shili D, Seitova A, Miller J, Khosraviani N, Penn A, Ho B, Sanchez O, Hande MP, Masson JY, Brown GW, Alaoui-Jamali M, Reynolds JJ, Arrowsmith C, Raught B, Pujana MA, Mekhail K, Stewart GS, Hakem A, Hakem R. Krishnan R, et al. Among authors: seitova a. Nucleic Acids Res. 2023 Oct 27;51(19):10484-10505. doi: 10.1093/nar/gkad733. Nucleic Acids Res. 2023. PMID: 37697435 Free PMC article.
Structures of the cGMP-dependent protein kinase in malaria parasites reveal a unique structural relay mechanism for activation.
El Bakkouri M, Kouidmi I, Wernimont AK, Amani M, Hutchinson A, Loppnau P, Kim JJ, Flueck C, Walker JR, Seitova A, Senisterra G, Kakihara Y, Kim C, Blackman MJ, Calmettes C, Baker DA, Hui R. El Bakkouri M, et al. Among authors: seitova a. Proc Natl Acad Sci U S A. 2019 Jul 9;116(28):14164-14173. doi: 10.1073/pnas.1905558116. Epub 2019 Jun 25. Proc Natl Acad Sci U S A. 2019. PMID: 31239348 Free PMC article.
Crystallization and preliminary X-ray diffraction analysis of human dipeptidyl peptidase 10 (DPPY), a component of voltage-gated potassium channels.
Bezerra GA, Dobrovetsky E, Seitova A, Dhe-Paganon S, Gruber K. Bezerra GA, et al. Among authors: seitova a. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Feb 1;68(Pt 2):214-7. doi: 10.1107/S1744309111055230. Epub 2012 Jan 26. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012. PMID: 22298003 Free PMC article.
Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex.
Ivanochko D, Halabelian L, Henderson E, Savitsky P, Jain H, Marcon E, Duan S, Hutchinson A, Seitova A, Barsyte-Lovejoy D, Filippakopoulos P, Greenblatt J, Lima-Fernandes E, Arrowsmith CH. Ivanochko D, et al. Among authors: seitova a. Nucleic Acids Res. 2019 Feb 20;47(3):1225-1238. doi: 10.1093/nar/gky1192. Nucleic Acids Res. 2019. PMID: 30462309 Free PMC article.
Design and characterization of mutant and wildtype huntingtin proteins produced from a toolkit of scalable eukaryotic expression systems.
Harding RJ, Loppnau P, Ackloo S, Lemak A, Hutchinson A, Hunt B, Holehouse AS, Ho JC, Fan L, Toledo-Sherman L, Seitova A, Arrowsmith CH. Harding RJ, et al. Among authors: seitova a. J Biol Chem. 2019 Apr 26;294(17):6986-7001. doi: 10.1074/jbc.RA118.007204. Epub 2019 Mar 6. J Biol Chem. 2019. PMID: 30842263 Free PMC article.
Delineation of functional subdomains of Huntingtin protein and their interaction with HAP40.
Alteen MG, Deme JC, Alvarez CP, Loppnau P, Hutchinson A, Seitova A, Chandrasekaran R, Silva Ramos E, Secker C, Alqazzaz M, Wanker EE, Lea SM, Arrowsmith CH, Harding RJ. Alteen MG, et al. Among authors: seitova a. Structure. 2023 Sep 7;31(9):1121-1131.e6. doi: 10.1016/j.str.2023.06.002. Epub 2023 Jun 29. Structure. 2023. PMID: 37390814 Free PMC article.
Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5.
Senisterra G, Wu H, Allali-Hassani A, Wasney GA, Barsyte-Lovejoy D, Dombrovski L, Dong A, Nguyen KT, Smil D, Bolshan Y, Hajian T, He H, Seitova A, Chau I, Li F, Poda G, Couture JF, Brown PJ, Al-Awar R, Schapira M, Arrowsmith CH, Vedadi M. Senisterra G, et al. Among authors: seitova a. Biochem J. 2013 Jan 1;449(1):151-9. doi: 10.1042/BJ20121280. Biochem J. 2013. PMID: 22989411 Free PMC article.
33 results