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Spontaneous HIV expression during suppressive ART is associated with the magnitude and function of HIV-specific CD4+ and CD8+ T cells.
Dubé M, Tastet O, Dufour C, Sannier G, Brassard N, Delgado GG, Pagliuzza A, Richard C, Nayrac M, Routy JP, Prat A, Estes JD, Fromentin R, Chomont N, Kaufmann DE. Dubé M, et al. Among authors: routy jp. Cell Host Microbe. 2023 Sep 13;31(9):1507-1522.e5. doi: 10.1016/j.chom.2023.08.006. Cell Host Microbe. 2023. PMID: 37708853 Free PMC article.
Longitudinal assessment of changes in HIV-specific effector activity in HIV-infected patients starting highly active antiretroviral therapy in primary infection.
Alter G, Hatzakis G, Tsoukas CM, Pelley K, Rouleau D, LeBlanc R, Baril JG, Dion H, Lefebvre E, Thomas R, Côté P, Lapointe N, Routy JP, Sékaly RP, Conway B, Bernard NF. Alter G, et al. Among authors: routy jp. J Immunol. 2003 Jul 1;171(1):477-88. doi: 10.4049/jimmunol.171.1.477. J Immunol. 2003. PMID: 12817033
Transcription factor FOXO3a controls the persistence of memory CD4(+) T cells during HIV infection.
van Grevenynghe J, Procopio FA, He Z, Chomont N, Riou C, Zhang Y, Gimmig S, Boucher G, Wilkinson P, Shi Y, Yassine-Diab B, Said EA, Trautmann L, El Far M, Balderas RS, Boulassel MR, Routy JP, Haddad EK, Sekaly RP. van Grevenynghe J, et al. Among authors: routy jp. Nat Med. 2008 Mar;14(3):266-74. doi: 10.1038/nm1728. Epub 2008 Mar 2. Nat Med. 2008. PMID: 18311149
HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation.
Chomont N, El-Far M, Ancuta P, Trautmann L, Procopio FA, Yassine-Diab B, Boucher G, Boulassel MR, Ghattas G, Brenchley JM, Schacker TW, Hill BJ, Douek DC, Routy JP, Haddad EK, Sékaly RP. Chomont N, et al. Among authors: routy jp. Nat Med. 2009 Aug;15(8):893-900. doi: 10.1038/nm.1972. Epub 2009 Jun 21. Nat Med. 2009. PMID: 19543283 Free PMC article. Clinical Trial.
Changes in function of HIV-specific T-cell responses with increasing time from infection.
Ndongala ML, Kamya P, Boulet S, Peretz Y, Rouleau D, Tremblay C, Leblanc R, Côté P, Baril JG, Thomas R, Vézina S, Boulassel MR, Routy JP, Sékaly RP, Bernard NF. Ndongala ML, et al. Among authors: routy jp. Viral Immunol. 2010 Apr;23(2):159-68. doi: 10.1089/vim.2009.0084. Viral Immunol. 2010. PMID: 20373996 Free PMC article.
477 results