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Formate Supplementation Enhances Antitumor CD8+ T-cell Fitness and Efficacy of PD-1 Blockade.
Rowe JH, Elia I, Shahid O, Gaudiano EF, Sifnugel NE, Johnson S, Reynolds AG, Fung ME, Joshi S, LaFleur MW, Park JS, Pauken KE, Rabinowitz JD, Freeman GJ, Haigis MC, Sharpe AH. Rowe JH, et al. Among authors: freeman gj. Cancer Discov. 2023 Dec 12;13(12):2566-2583. doi: 10.1158/2159-8290.CD-22-1301. Cancer Discov. 2023. PMID: 37728660 Free PMC article.
PD-L2 is a second ligand for PD-1 and inhibits T cell activation.
Latchman Y, Wood CR, Chernova T, Chaudhary D, Borde M, Chernova I, Iwai Y, Long AJ, Brown JA, Nunes R, Greenfield EA, Bourque K, Boussiotis VA, Carter LL, Carreno BM, Malenkovich N, Nishimura H, Okazaki T, Honjo T, Sharpe AH, Freeman GJ. Latchman Y, et al. Among authors: freeman gj. Nat Immunol. 2001 Mar;2(3):261-8. doi: 10.1038/85330. Nat Immunol. 2001. PMID: 11224527
B7-dependent T-cell costimulation in mice lacking CD28 and CTLA4.
Mandelbrot DA, Oosterwegel MA, Shimizu K, Yamada A, Freeman GJ, Mitchell RN, Sayegh MH, Sharpe AH. Mandelbrot DA, et al. Among authors: freeman gj. J Clin Invest. 2001 Apr;107(7):881-7. doi: 10.1172/JCI11710. J Clin Invest. 2001. PMID: 11285307 Free PMC article.
ICOS is critical for CD40-mediated antibody class switching.
McAdam AJ, Greenwald RJ, Levin MA, Chernova T, Malenkovich N, Ling V, Freeman GJ, Sharpe AH. McAdam AJ, et al. Among authors: freeman gj. Nature. 2001 Jan 4;409(6816):102-5. doi: 10.1038/35051107. Nature. 2001. PMID: 11343122
446 results