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CMC Regulatory Considerations for Antibody-Drug Conjugates.
Bechtold-Peters K, Ruggiero A, Vriezen N, Ihle N, Klein A, Morgan C, Schweizer D, Liu D, Jacobson F, Buecheler J, Panek M, Duggan N, Malyala P, Dupraz P, Desai P, Niu S, Feng Y, Wang X. Bechtold-Peters K, et al. Among authors: jacobson f. J Pharm Sci. 2023 Dec;112(12):2965-2980. doi: 10.1016/j.xphs.2023.09.007. Epub 2023 Sep 21. J Pharm Sci. 2023. PMID: 37741455 Review.
Investigation of low recovery in the free drug assay for antibody drug conjugates by size exclusion-reversed phase two dimensional-liquid chromatography.
Li Y, Stella C, Zheng L, Bechtel C, Gruenhagen J, Jacobson F, Medley CD. Li Y, et al. Among authors: jacobson f. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Oct 1;1032:112-118. doi: 10.1016/j.jchromb.2016.05.011. Epub 2016 May 10. J Chromatogr B Analyt Technol Biomed Life Sci. 2016. PMID: 27212187
Statistical characterization of therapeutic protein modifications.
Tsai TH, Hao Z, Hong Q, Moore B, Stella C, Zhang JH, Chen Y, Kim M, Koulis T, Ryslik GA, Verschueren E, Jacobson F, Haskins WE, Vitek O. Tsai TH, et al. Among authors: jacobson f. Sci Rep. 2017 Aug 11;7(1):7896. doi: 10.1038/s41598-017-08333-y. Sci Rep. 2017. PMID: 28801661 Free PMC article.
Protein aggregation and bioprocessing.
Cromwell ME, Hilario E, Jacobson F. Cromwell ME, et al. Among authors: jacobson f. AAPS J. 2006 Sep 15;8(3):E572-9. doi: 10.1208/aapsj080366. AAPS J. 2006. PMID: 17025275 Free PMC article. Review.
249 results