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Clinical phenotypes and outcomes in children with multisystem inflammatory syndrome across SARS-CoV-2 variant eras: a multinational study from the 4CE consortium.
Sperotto F, Gutiérrez-Sacristán A, Makwana S, Li X, Rofeberg VN, Cai T, Bourgeois FT, Omenn GS, Hanauer DA, Sáez C, Bonzel CL, Bucholz E, Dionne A, Elias MD, García-Barrio N, González TG, Issitt RW, Kernan KF, Laird-Gion J, Maidlow SE, Mandl KD, Ahooyi TM, Moraleda C, Morris M, Moshal KL, Pedrera-Jiménez M, Shah MA, South AM, Spiridou A, Taylor DM, Verdy G, Visweswaran S, Wang X, Xia Z, Zachariasse JM; Consortium for Clinical Characterization of COVID-19 by EHR (4CE); Newburger JW, Avillach P. Sperotto F, et al. Among authors: kernan kf. EClinicalMedicine. 2023 Sep 14;64:102212. doi: 10.1016/j.eclinm.2023.102212. eCollection 2023 Oct. EClinicalMedicine. 2023. PMID: 37745025 Free PMC article.
International comparisons of laboratory values from the 4CE collaborative to predict COVID-19 mortality.
Weber GM, Hong C, Xia Z, Palmer NP, Avillach P, L'Yi S, Keller MS, Murphy SN, Gutiérrez-Sacristán A, Bonzel CL, Serret-Larmande A, Neuraz A, Omenn GS, Visweswaran S, Klann JG, South AM, Loh NHW, Cannataro M, Beaulieu-Jones BK, Bellazzi R, Agapito G, Alessiani M, Aronow BJ, Bell DS, Benoit V, Bourgeois FT, Chiovato L, Cho K, Dagliati A, DuVall SL, Barrio NG, Hanauer DA, Ho YL, Holmes JH, Issitt RW, Liu M, Luo Y, Lynch KE, Maidlow SE, Malovini A, Mandl KD, Mao C, Matheny ME, Moore JH, Morris JS, Morris M, Mowery DL, Ngiam KY, Patel LP, Pedrera-Jimenez M, Ramoni RB, Schriver ER, Schubert P, Balazote PS, Spiridou A, Tan ALM, Tan BWL, Tibollo V, Torti C, Trecarichi EM, Wang X; Consortium for Clinical Characterization of COVID-19 by EHR (4CE); Kohane IS, Cai T, Brat GA. Weber GM, et al. NPJ Digit Med. 2022 Jun 13;5(1):74. doi: 10.1038/s41746-022-00601-0. NPJ Digit Med. 2022. PMID: 35697747 Free PMC article.
Acute Disorders of Consciousness in Pediatric Severe Sepsis and Organ Failure: Secondary Analysis of the Multicenter Phenotyping Sepsis-Induced Multiple Organ Failure Study.
Cheung C, Kernan KF, Berg RA, Zuppa AF, Notterman DA, Pollack MM, Wessel D, Meert KL, Hall MW, Newth C, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Banks RK, Reeder RW, Holubkov R, Carcillo JA, Fink EL; on behalf of the Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network. Cheung C, et al. Among authors: kernan kf. Pediatr Crit Care Med. 2023 Oct 1;24(10):840-848. doi: 10.1097/PCC.0000000000003300. Epub 2023 Jun 14. Pediatr Crit Care Med. 2023. PMID: 37314247 Free PMC article.
Machine learning derivation of four computable 24-h pediatric sepsis phenotypes to facilitate enrollment in early personalized anti-inflammatory clinical trials.
Qin Y, Kernan KF, Fan Z, Park HJ, Kim S, Canna SW, Kellum JA, Berg RA, Wessel D, Pollack MM, Meert K, Hall M, Newth C, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Banks R, Reeder RW, Holubkov R, Notterman DA, Michael Dean J, Carcillo JA. Qin Y, et al. Among authors: kernan kf. Crit Care. 2022 May 7;26(1):128. doi: 10.1186/s13054-022-03977-3. Crit Care. 2022. PMID: 35526000 Free PMC article.
Hyperferritinemia and inflammation.
Kernan KF, Carcillo JA. Kernan KF, et al. Int Immunol. 2017 Nov 1;29(9):401-409. doi: 10.1093/intimm/dxx031. Int Immunol. 2017. PMID: 28541437 Free PMC article. Review.
Prevalence of Pathogenic and Potentially Pathogenic Inborn Error of Immunity Associated Variants in Children with Severe Sepsis.
Kernan KF, Ghaloul-Gonzalez L, Vockley J, Lamb J, Hollingshead D, Chandran U, Sethi R, Park HJ, Berg RA, Wessel D, Pollack MM, Meert KL, Hall MW, Newth CJL, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Banks R, Reeder RW, Holubkov R, Notterman DA, Dean JM, Carcillo JA. Kernan KF, et al. J Clin Immunol. 2022 Feb;42(2):350-364. doi: 10.1007/s10875-021-01183-4. Epub 2022 Jan 1. J Clin Immunol. 2022. PMID: 34973142 Free PMC article.
35 results