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Page 1
Plasma cell differentiation, antibody quality, and initial germinal center B cell population depend on glucose influx rate.
Brookens SK, Cho SH, Paik Y, Meyer K, Raybuck AL, Park C, Greenwood DL, Rathmell JC, Boothby MR. Brookens SK, et al. Among authors: rathmell jc. bioRxiv [Preprint]. 2023 Sep 16:2023.09.13.557599. doi: 10.1101/2023.09.13.557599. bioRxiv. 2023. Update in: J Immunol. 2024 Jan 1;212(1):43-56. doi: 10.4049/jimmunol.2200756. PMID: 37745429 Free PMC article. Updated. Preprint.
MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function.
Sugiura A, Andrejeva G, Voss K, Heintzman DR, Xu X, Madden MZ, Ye X, Beier KL, Chowdhury NU, Wolf MM, Young AC, Greenwood DL, Sewell AE, Shahi SK, Freedman SN, Cameron AM, Foerch P, Bourne T, Garcia-Canaveras JC, Karijolich J, Newcomb DC, Mangalam AK, Rabinowitz JD, Rathmell JC. Sugiura A, et al. Among authors: rathmell jc. Immunity. 2022 Jan 11;55(1):65-81.e9. doi: 10.1016/j.immuni.2021.10.011. Epub 2021 Nov 11. Immunity. 2022. PMID: 34767747 Free PMC article.
Neutrophil trafficking to the site of infection requires Cpt1a-dependent fatty acid β-oxidation.
Pham L, Komalavilas P, Eddie AM, Thayer TE, Greenwood DL, Liu KH, Weinberg J, Patterson A, Fessel JP, Boyd KL, Schafer JC, Kuck JL, Shaver AC, Flaherty DK, Matlock BK, Wijers CDM, Serezani CH, Jones DP, Brittain EL, Rathmell JC, Noto MJ. Pham L, et al. Among authors: rathmell jc. Commun Biol. 2022 Dec 13;5(1):1366. doi: 10.1038/s42003-022-04339-z. Commun Biol. 2022. PMID: 36513703 Free PMC article.
Acly Deficiency Enhances Myelopoiesis through Acetyl Coenzyme A and Metabolic-Epigenetic Cross-Talk.
Greenwood DL, Ramsey HE, Nguyen PTT, Patterson AR, Voss K, Bader JE, Sugiura A, Bacigalupa ZA, Schaefer S, Ye X, Dahunsi DO, Madden MZ, Wellen KE, Savona MR, Ferrell PB, Rathmell JC. Greenwood DL, et al. Among authors: rathmell jc. Immunohorizons. 2022 Dec 1;6(12):837-850. doi: 10.4049/immunohorizons.2200086. Immunohorizons. 2022. PMID: 36547387 Free PMC article.
Lactate Utilization Enables Metabolic Escape to Confer Resistance to BET Inhibition in Acute Myeloid Leukemia.
Monteith AJ, Ramsey HE, Silver AJ, Brown D, Greenwood D, Smith BN, Wise AD, Liu J, Olmstead SD, Watke J, Arrate MP, Gorska AE, Fuller L, Locasale JW, Stubbs MC, Rathmell JC, Savona MR. Monteith AJ, et al. Among authors: rathmell jc. Cancer Res. 2024 Apr 1;84(7):1101-1114. doi: 10.1158/0008-5472.CAN-23-0291. Cancer Res. 2024. PMID: 38285895 Free PMC article.
Functional Overlap of Inborn Errors of Immunity and Metabolism Genes Define T Cell Immunometabolic Vulnerabilities.
Patterson AR, Needle GA, Sugiura A, Chi C, Steiner KK, Fisher EL, Robertson GL, Bodnya C, Markle JG, Gama V, Rathmell JC. Patterson AR, et al. Among authors: rathmell jc. bioRxiv [Preprint]. 2023 Jan 24:2023.01.24.525419. doi: 10.1101/2023.01.24.525419. bioRxiv. 2023. Update in: Sci Immunol. 2024 Aug 16;9(98):eadh0368. doi: 10.1126/sciimmunol.adh0368. PMID: 36747715 Free PMC article. Updated. Preprint.
Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability.
Abbott KL, Ali A, Reinfeld BI, Deik A, Subudhi S, Landis MD, Hongo RA, Young KL, Kunchok T, Nabel CS, Crowder KD, Kent JR, Madariaga MLL, Jain RK, Beckermann KE, Lewis CA, Clish CB, Muir A, Rathmell WK, Rathmell JC, Vander Heiden MG. Abbott KL, et al. Among authors: rathmell jc, rathmell wk. bioRxiv [Preprint]. 2024 Apr 8:2023.12.24.573250. doi: 10.1101/2023.12.24.573250. bioRxiv. 2024. Update in: Elife. 2024 May 24;13:RP95652. doi: 10.7554/eLife.95652. PMID: 38187626 Free PMC article. Updated. Preprint.
230 results