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Microglial-Targeted nSMase2 Inhibitor Fails to Reduce Tau Propagation in PS19 Mice.
Huang M, Tallon C, Zhu X, Huizar KDJ, Picciolini S, Thomas AG, Tenora L, Liyanage W, Rodà F, Gualerzi A, Kannan RM, Bedoni M, Rais R, Slusher BS. Huang M, et al. Among authors: kannan rm. Pharmaceutics. 2023 Sep 21;15(9):2364. doi: 10.3390/pharmaceutics15092364. Pharmaceutics. 2023. PMID: 37765332 Free PMC article.
Neuroprotective effects of a dendrimer-based glutamate carboxypeptidase inhibitor on superoxide dismutase transgenic mice after neonatal hypoxic-ischemic brain injury.
Arteaga Cabeza O, Zhang Z, Smith Khoury E, Sheldon RA, Sharma A, Zhang F, Slusher BS, Kannan RM, Kannan S, Ferriero DM. Arteaga Cabeza O, et al. Among authors: kannan rm, kannan s. Neurobiol Dis. 2021 Jan;148:105201. doi: 10.1016/j.nbd.2020.105201. Epub 2020 Nov 30. Neurobiol Dis. 2021. PMID: 33271328 Free PMC article.
Dendrimer-2PMPA selectively blocks upregulated microglial GCPII activity and improves cognition in a mouse model of multiple sclerosis.
Hollinger KR, Sharma A, Tallon C, Lovell L, Thomas AG, Zhu X, Wiseman R, Wu Y, Kambhampati SP, Liaw K, Sharma R, Rojas C, Rais R, Kannan S, Kannan RM, Slusher BS. Hollinger KR, et al. Among authors: kannan rm, kannan s. Nanotheranostics. 2022 Jan 1;6(2):126-142. doi: 10.7150/ntno.63158. eCollection 2022. Nanotheranostics. 2022. PMID: 34976589 Free PMC article.
Dendrimer-2PMPA Delays Muscle Function Loss and Denervation in a Murine Model of Amyotrophic Lateral Sclerosis.
Tallon C, Sharma A, Zhang Z, Thomas AG, Ng J, Zhu X, Donoghue A, Schulte M, Joe TR, Kambhampati SP, Sharma R, Liaw K, Kannan S, Kannan RM, Slusher BS. Tallon C, et al. Among authors: kannan rm, kannan s. Neurotherapeutics. 2022 Jan;19(1):274-288. doi: 10.1007/s13311-021-01159-7. Epub 2022 Jan 4. Neurotherapeutics. 2022. PMID: 34984651 Free PMC article.
Dendrimer-Conjugated nSMase2 Inhibitor Reduces Tau Propagation in Mice.
Tallon C, Bell BJ, Sharma A, Pal A, Malvankar MM, Thomas AG, Yoo SW, Hollinger KR, Coleman K, Wilkinson EL, Kannan S, Haughey NJ, Kannan RM, Rais R, Slusher BS. Tallon C, et al. Among authors: kannan rm, kannan s. Pharmaceutics. 2022 Sep 28;14(10):2066. doi: 10.3390/pharmaceutics14102066. Pharmaceutics. 2022. PMID: 36297501 Free PMC article.
125 results