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Reliable identification of cardiac conduction abnormalities in drug discovery using automated patch clamp II: Best practices for Nav1.5 peak current in a high throughput screening environment.
Rotordam MG, Obergrussberger A, Brinkwirth N, Takasuna K, Becker N, Horváth A, Goetze TA, Rapedius M, Furukawa H, Hasegawa Y, Oka T, Fertig N, Stoelzle-Feix S. Rotordam MG, et al. Among authors: oka t. J Pharmacol Toxicol Methods. 2021 Nov-Dec;112:107125. doi: 10.1016/j.vascn.2021.107125. Epub 2021 Sep 6. J Pharmacol Toxicol Methods. 2021. PMID: 34500078
Reliable identification of cardiac liability in drug discovery using automated patch clamp: Benchmarking best practices and calibration standards for improved proarrhythmic assessment.
Brinkwirth N, Takasuna K, Doi M, Becker N, Obergrussberger A, Friis S, Furukawa H, Hasegawa Y, Oka T, Ohtsuki A, Fertig N, Stoelzle-Feix S. Brinkwirth N, et al. Among authors: oka t. J Pharmacol Toxicol Methods. 2020 Sep;105:106884. doi: 10.1016/j.vascn.2020.106884. Epub 2020 Jun 18. J Pharmacol Toxicol Methods. 2020. PMID: 32565325
Automated Patch Clamp Meets High-Throughput Screening: 384 Cells Recorded in Parallel on a Planar Patch Clamp Module.
Obergrussberger A, Brüggemann A, Goetze TA, Rapedius M, Haarmann C, Rinke I, Becker N, Oka T, Ohtsuki A, Stengel T, Vogel M, Steindl J, Mueller M, Stiehler J, George M, Fertig N. Obergrussberger A, et al. Among authors: oka t. J Lab Autom. 2016 Dec;21(6):779-793. doi: 10.1177/2211068215623209. Epub 2015 Dec 23. J Lab Autom. 2016. PMID: 26702021
Comparative analysis of gut microbiota in hormone-sensitive and castration-resistant prostate cancer in Japanese men.
Fujimoto S, Hatano K, Banno E, Motooka D, De Velasco MA, Kura Y, Toyoda S, Hashimoto M, Adomi S, Minami T, Yoshimura K, Oka T, Hata J, Matsushita M, Takao T, Takada S, Tsujimura A, Kojima Y, Obara W, Nakamura S, Uemura H, Nonomura N, Fujita K. Fujimoto S, et al. Among authors: oka t. Cancer Sci. 2024 Dec 3. doi: 10.1111/cas.16408. Online ahead of print. Cancer Sci. 2024. PMID: 39628067 Free article.
MS-DIAL 5 multimodal mass spectrometry data mining unveils lipidome complexities.
Takeda H, Matsuzawa Y, Takeuchi M, Takahashi M, Nishida K, Harayama T, Todoroki Y, Shimizu K, Sakamoto N, Oka T, Maekawa M, Chung MH, Kurizaki Y, Kiuchi S, Tokiyoshi K, Buyantogtokh B, Kurata M, Kvasnička A, Takeda U, Uchino H, Hasegawa M, Miyamoto J, Tanabe K, Takeda S, Mori T, Kumakubo R, Tanaka T, Yoshino T, Okamoto M, Takahashi H, Arita M, Tsugawa H. Takeda H, et al. Among authors: oka t. Nat Commun. 2024 Nov 28;15(1):9903. doi: 10.1038/s41467-024-54137-w. Nat Commun. 2024. PMID: 39609386 Free PMC article.
2,878 results