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Page 1
Novel Corrector for Variants of SLC6A8: A Therapeutic Opportunity for Creatine Transporter Deficiency.
Gechijian LN, Muncipinto G, Rettenmaier TJ, Labenski MT, Rusu V, Rosskamp L, Conway L, van Kalken D, Gross L, Iantosca G, Crotty W, Mathis R, Park H, Rabin B, Westgate C, Lyons M, Deshusses C, Brandon N, Brown DG, Blanchette HS, Pullen N, Jones LH, Barrish JC. Gechijian LN, et al. Among authors: jones lh. ACS Chem Biol. 2024 Nov 15;19(11):2372-2382. doi: 10.1021/acschembio.4c00571. Epub 2024 Oct 17. ACS Chem Biol. 2024. PMID: 39418577 Free PMC article.
Development of a covalent cereblon-based PROTAC employing a fluorosulfate warhead.
Nowak RP, Ragosta L, Huerta F, Liu H, Ficarro SB, Cruite JT, Metivier RJ, Donovan KA, Marto JA, Fischer ES, Zerfas BL, Jones LH. Nowak RP, et al. Among authors: jones lh. RSC Chem Biol. 2023 Aug 31;4(11):906-912. doi: 10.1039/d3cb00103b. eCollection 2023 Nov 1. RSC Chem Biol. 2023. PMID: 37920397 Free PMC article.
The promise of targeted protein degradation approaches.
Daniels DL, Sapkota GP, Jones LH. Daniels DL, et al. Among authors: jones lh. Trends Pharmacol Sci. 2023 Nov;44(11):746-749. doi: 10.1016/j.tips.2023.08.015. Epub 2023 Sep 28. Trends Pharmacol Sci. 2023. PMID: 37775456 No abstract available.
ReSPONDINg TACtically, degrading strategically.
Zerfas BL, Jones LH. Zerfas BL, et al. Among authors: jones lh. Trends Pharmacol Sci. 2023 Nov;44(11):753-754. doi: 10.1016/j.tips.2023.08.010. Epub 2023 Sep 7. Trends Pharmacol Sci. 2023. PMID: 37689534
Clinical Translation of Targeted Protein Degraders.
Kong NR, Jones LH. Kong NR, et al. Among authors: jones lh. Clin Pharmacol Ther. 2023 Sep;114(3):558-568. doi: 10.1002/cpt.2985. Epub 2023 Jul 17. Clin Pharmacol Ther. 2023. PMID: 37399310 Review.
190 results