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Exploiting the therapeutic vulnerability of IDH-mutant gliomas with zotiraciclib.
Pang Y, Li Q, Sergi Z, Yu G, Sang X, Kim O, Wang H, Ranjan A, Merchant M, Oudit B, Robey RW, Soheilian F, Tran B, Núñez FJ, Zhang M, Song H, Zhang W, Davis D, Gilbert MR, Gottesman MM, Liu Z, Khan J, Thomas CJ, Castro MG, Gujral TS, Wu J. Pang Y, et al. Among authors: gujral ts. bioRxiv [Preprint]. 2024 Jan 2:2023.06.29.547143. doi: 10.1101/2023.06.29.547143. bioRxiv. 2024. PMID: 37786680 Free PMC article. Preprint.
Microfluidic Modulation of Microvasculature in Microdissected Tumors.
Nguyen TNH, Horowitz LF, Nguyen B, Lockhart E, Zhu S, Gujral TS, Folch A. Nguyen TNH, et al. Among authors: gujral ts. bioRxiv [Preprint]. 2024 Oct 7:2024.09.26.615278. doi: 10.1101/2024.09.26.615278. bioRxiv. 2024. PMID: 39386436 Free PMC article. Preprint.
Microdissected tumor cuboids: a microscale cancer model for large-scale testing that retains a complex tumor microenvironment.
Horowitz LF, Rodríguez-Mias RA, Chang M, Zhu S, Gottshall NR, Stepanov I, Stiles C, Yeung M, Nguyen TN, Lockhart EJ, Yeung RS, Villen J, Gujral TS, Folch A. Horowitz LF, et al. Among authors: gujral ts. bioRxiv [Preprint]. 2024 Nov 1:2024.03.22.586189. doi: 10.1101/2024.03.22.586189. bioRxiv. 2024. PMID: 38585935 Free PMC article. Preprint.
Low-Cost Robotic Manipulation of Live Microtissues for Cancer Drug Testing.
Stepanov I, Gottshall NR, Ahmadianyazdi A, Sinha D, Lockhart EJ, Nguyen TNH, Hassan S, Horowitz LF, Yeung RS, Gujral TS, Folch A. Stepanov I, et al. Among authors: gujral ts. bioRxiv [Preprint]. 2024 Aug 6:2024.03.21.586169. doi: 10.1101/2024.03.21.586169. bioRxiv. 2024. PMID: 38586030 Free PMC article. Preprint.
DNAJB1-PRKACA fusion drives fibrolamellar liver cancer through impaired SIK signaling and CRTC2/p300-mediated transcriptional reprogramming.
Gritti I, Wan J, Weeresekara V, Vaz JM, Tarantino G, Bryde TH, Vijay V, Kammula AV, Kattel P, Zhu S, Vu P, Chan M, Wu MJ, Gordan JD, Patra KC, Silveira VS, Manguso RT, Wein MN, Ott CJ, Qi J, Liu D, Sakamoto K, Gujral TS, Bardeesy N. Gritti I, et al. Among authors: gujral ts. Cancer Discov. 2024 Sep 27. doi: 10.1158/2159-8290.CD-24-0634. Online ahead of print. Cancer Discov. 2024. PMID: 39326063
Proteo-metabolomics and patient tumor slice experiments point to amino acid centrality for rewired mitochondria in fibrolamellar carcinoma.
Long D Jr, Chan M, Han M, Kamdar Z, Ma RK, Tsai PY, Francisco AB, Barrow J, Shackelford DB, Yarchoan M, McBride MJ, Orre LM, Vacanti NM, Gujral TS, Sethupathy P. Long D Jr, et al. Among authors: gujral ts. Cell Rep Med. 2024 Sep 17;5(9):101699. doi: 10.1016/j.xcrm.2024.101699. Epub 2024 Aug 28. Cell Rep Med. 2024. PMID: 39208801 Free PMC article.
DNAJB1-PRKACA fusion protein-regulated LINC00473 promotes tumor growth and alters mitochondrial fitness in fibrolamellar carcinoma.
Ma RK, Tsai PY, Farghli AR, Shumway A, Kanke M, Gordan JD, Gujral TS, Vakili K, Nukaya M, Noetzli L, Ronnekleiv-Kelly S, Broom W, Barrow J, Sethupathy P. Ma RK, et al. Among authors: gujral ts. PLoS Genet. 2024 Mar 21;20(3):e1011216. doi: 10.1371/journal.pgen.1011216. eCollection 2024 Mar. PLoS Genet. 2024. PMID: 38512964 Free PMC article.
55 results