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Page 1
European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation.
Budu-Aggrey A, Kilanowski A, Sobczyk MK; 23andMe Research Team; Shringarpure SS, Mitchell R, Reis K, Reigo A; Estonian Biobank Research Team; Mägi R, Nelis M, Tanaka N, Brumpton BM, Thomas LF, Sole-Navais P, Flatley C, Espuela-Ortiz A, Herrera-Luis E, Lominchar JVT, Bork-Jensen J, Marenholz I, Arnau-Soler A, Jeong A, Fawcett KA, Baurecht H, Rodriguez E, Alves AC, Kumar A, Sleiman PM, Chang X, Medina-Gomez C, Hu C, Xu CJ, Qi C, El-Heis S, Titcombe P, Antoun E, Fadista J, Wang CA, Thiering E, Wu B, Kress S, Kothalawala DM, Kadalayil L, Duan J, Zhang H, Hadebe S, Hoffmann T, Jorgenson E, Choquet H, Risch N, Njølstad P, Andreassen OA, Johansson S, Almqvist C, Gong T, Ullemar V, Karlsson R, Magnusson PKE, Szwajda A, Burchard EG, Thyssen JP, Hansen T, Kårhus LL, Dantoft TM, Jeanrenaud ACSN, Ghauri A, Arnold A, Homuth G, Lau S, Nöthen MM, Hübner N, Imboden M, Visconti A, Falchi M, Bataille V, Hysi P, Ballardini N, Boomsma DI, Hottenga JJ, Müller-Nurasyid M, Ahluwalia TS, Stokholm J, Chawes B, Schoos AM, Esplugues A, Bustamante M, Raby B, Arshad S, German C, Esko T, Milani LA, Metspalu A, Terao C, Abuabara K, Løset M, Hveem K, Jacobsson B, Pino-Yanes M, Strachan DP, Grarup N, Linne… See abstract for full author list ➔ Budu-Aggrey A, et al. Among authors: arnau soler a. Nat Commun. 2023 Oct 4;14(1):6172. doi: 10.1038/s41467-023-41180-2. Nat Commun. 2023. PMID: 37794016 Free PMC article.
Rare variant analysis in eczema identifies exonic variants in DUSP1, NOTCH4 and SLC9A4.
Grosche S, Marenholz I, Esparza-Gordillo J, Arnau-Soler A, Pairo-Castineira E, Rüschendorf F, Ahluwalia TS, Almqvist C, Arnold A; Australian Asthma Genetics Consortium (AAGC); Baurecht H, Bisgaard H, Bønnelykke K, Brown SJ, Bustamante M, Curtin JA, Custovic A, Dharmage SC, Esplugues A, Falchi M, Fernandez-Orth D, Ferreira MAR, Franke A, Gerdes S, Gieger C, Hakonarson H, Holt PG, Homuth G, Hubner N, Hysi PG, Jarvelin MR, Karlsson R, Koppelman GH, Lau S, Lutz M, Magnusson PKE, Marks GB, Müller-Nurasyid M, Nöthen MM, Paternoster L, Pennell CE, Peters A, Rawlik K, Robertson CF, Rodriguez E, Sebert S, Simpson A, Sleiman PMA, Standl M, Stölzl D, Strauch K, Szwajda A, Tenesa A, Thompson PJ, Ullemar V, Visconti A, Vonk JM, Wang CA, Weidinger S, Wielscher M, Worth CL, Xu CJ, Lee YA. Grosche S, et al. Among authors: arnau soler a. Nat Commun. 2021 Nov 16;12(1):6618. doi: 10.1038/s41467-021-26783-x. Nat Commun. 2021. PMID: 34785669 Free PMC article.
Filaggrin loss-of-function mutations are associated with persistence of egg and milk allergy.
Kalb B, Marenholz I, Jeanrenaud ACSN, Meixner L, Arnau-Soler A, Rosillo-Salazar OD, Ghauri A, Cibin P, Blümchen K, Schlags R, Hansen G, Seidenberg J, Keil T, Lau S, Niggemann B, Beyer K, Lee YA. Kalb B, et al. Among authors: arnau soler a. J Allergy Clin Immunol. 2022 Nov;150(5):1125-1134. doi: 10.1016/j.jaci.2022.05.018. Epub 2022 Jun 15. J Allergy Clin Immunol. 2022. PMID: 35714843 Free article.
An interdisciplinary approach to characterize peanut-allergic patients-First data from the FOOD@ consortium.
Worm M, Alexiou A, Höfer V, Birkner T, Jeanrenaud ACSN, Fauchère F, Pazur K, Steinert C, Arnau-Soler A, Banerjee P, Diefenbach A, Dobbertin-Welsch J, Dölle-Bierke S, Francuzik W, Ghauri A, Heller S, Kalb B, Löber U, Marenholz I, Markó L, Scheffel J, Potapenko O, Roll S, Lau S, Lee YA, Braun J, Thiel A, Babina M, Altrichter S, Forslund SK, Beyer K. Worm M, et al. Among authors: arnau soler a. Clin Transl Allergy. 2022 Oct 5;12(10):e12197. doi: 10.1002/clt2.12197. eCollection 2022 Oct. Clin Transl Allergy. 2022. PMID: 36225266 Free PMC article.
Genome-wide by environment interaction studies of depressive symptoms and psychosocial stress in UK Biobank and Generation Scotland.
Arnau-Soler A, Macdonald-Dunlop E, Adams MJ, Clarke TK, MacIntyre DJ, Milburn K, Navrady L; Generation Scotland; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Hayward C, McIntosh AM, Thomson PA. Arnau-Soler A, et al. Transl Psychiatry. 2019 Feb 4;9(1):14. doi: 10.1038/s41398-018-0360-y. Transl Psychiatry. 2019. PMID: 30718454 Free PMC article.
Genome-wide meta-analyses of stratified depression in Generation Scotland and UK Biobank.
Hall LS, Adams MJ, Arnau-Soler A, Clarke TK, Howard DM, Zeng Y, Davies G, Hagenaars SP, Maria Fernandez-Pujals A, Gibson J, Wigmore EM, Boutin TS, Hayward C, Scotland G; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Porteous DJ, Deary IJ, Thomson PA, Haley CS, McIntosh AM. Hall LS, et al. Among authors: arnau soler a. Transl Psychiatry. 2018 Jan 10;8(1):9. doi: 10.1038/s41398-017-0034-1. Transl Psychiatry. 2018. PMID: 29317602 Free PMC article.
DNA sequence-level analyses reveal potential phenotypic modifiers in a large family with psychiatric disorders.
Ryan NM, Lihm J, Kramer M, McCarthy S, Morris SW, Arnau-Soler A, Davies G, Duff B, Ghiban E, Hayward C, Deary IJ, Blackwood DHR, Lawrie SM, McIntosh AM, Evans KL, Porteous DJ, McCombie WR, Thomson PA. Ryan NM, et al. Among authors: arnau soler a. Mol Psychiatry. 2018 Dec;23(12):2254-2265. doi: 10.1038/s41380-018-0087-4. Epub 2018 Jun 7. Mol Psychiatry. 2018. PMID: 29880880 Free PMC article.
New insights from genetic studies of eczema.
Marenholz I, Arnau-Soler A, Rosillo-Salazar OD, Lee YA. Marenholz I, et al. Among authors: arnau soler a. Med Genet. 2023 Apr 5;35(1):33-45. doi: 10.1515/medgen-2023-2010. eCollection 2023 Apr. Med Genet. 2023. PMID: 38835414 Free PMC article.
A validation of the diathesis-stress model for depression in Generation Scotland.
Arnau-Soler A, Adams MJ, Clarke TK, MacIntyre DJ, Milburn K, Navrady L; Generation Scotland,; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Hayward C, McIntosh A, Thomson PA. Arnau-Soler A, et al. Transl Psychiatry. 2019 Jan 18;9(1):25. doi: 10.1038/s41398-018-0356-7. Transl Psychiatry. 2019. PMID: 30659167 Free PMC article.