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Page 1
European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation.
Budu-Aggrey A, Kilanowski A, Sobczyk MK; 23andMe Research Team; Shringarpure SS, Mitchell R, Reis K, Reigo A; Estonian Biobank Research Team; Mägi R, Nelis M, Tanaka N, Brumpton BM, Thomas LF, Sole-Navais P, Flatley C, Espuela-Ortiz A, Herrera-Luis E, Lominchar JVT, Bork-Jensen J, Marenholz I, Arnau-Soler A, Jeong A, Fawcett KA, Baurecht H, Rodriguez E, Alves AC, Kumar A, Sleiman PM, Chang X, Medina-Gomez C, Hu C, Xu CJ, Qi C, El-Heis S, Titcombe P, Antoun E, Fadista J, Wang CA, Thiering E, Wu B, Kress S, Kothalawala DM, Kadalayil L, Duan J, Zhang H, Hadebe S, Hoffmann T, Jorgenson E, Choquet H, Risch N, Njølstad P, Andreassen OA, Johansson S, Almqvist C, Gong T, Ullemar V, Karlsson R, Magnusson PKE, Szwajda A, Burchard EG, Thyssen JP, Hansen T, Kårhus LL, Dantoft TM, Jeanrenaud ACSN, Ghauri A, Arnold A, Homuth G, Lau S, Nöthen MM, Hübner N, Imboden M, Visconti A, Falchi M, Bataille V, Hysi P, Ballardini N, Boomsma DI, Hottenga JJ, Müller-Nurasyid M, Ahluwalia TS, Stokholm J, Chawes B, Schoos AM, Esplugues A, Bustamante M, Raby B, Arshad S, German C, Esko T, Milani LA, Metspalu A, Terao C, Abuabara K, Løset M, Hveem K, Jacobsson B, Pino-Yanes M, Strachan DP, Grarup N, Linne… See abstract for full author list ➔ Budu-Aggrey A, et al. Among authors: espuela ortiz a. Nat Commun. 2023 Oct 4;14(1):6172. doi: 10.1038/s41467-023-41180-2. Nat Commun. 2023. PMID: 37794016 Free PMC article.
Genomics of Treatable Traits in Asthma.
Espuela-Ortiz A, Martin-Gonzalez E, Poza-Guedes P, González-Pérez R, Herrera-Luis E. Espuela-Ortiz A, et al. Genes (Basel). 2023 Sep 20;14(9):1824. doi: 10.3390/genes14091824. Genes (Basel). 2023. PMID: 37761964 Free PMC article. Review.
Human genetics influences microbiome composition involved in asthma exacerbations despite inhaled corticosteroid treatment.
Perez-Garcia J, Espuela-Ortiz A, Hernández-Pérez JM, González-Pérez R, Poza-Guedes P, Martin-Gonzalez E, Eng C, Sardón-Prado O, Mederos-Luis E, Corcuera-Elosegui P, Sánchez-Machín I, Korta-Murua J, Villar J, Burchard EG, Lorenzo-Diaz F, Pino-Yanes M. Perez-Garcia J, et al. Among authors: espuela ortiz a. J Allergy Clin Immunol. 2023 Sep;152(3):799-806.e6. doi: 10.1016/j.jaci.2023.05.021. Epub 2023 Jun 8. J Allergy Clin Immunol. 2023. PMID: 37301411 Free PMC article.
The upper-airway microbiome as a biomarker of asthma exacerbations despite inhaled corticosteroid treatment.
Perez-Garcia J, González-Carracedo M, Espuela-Ortiz A, Hernández-Pérez JM, González-Pérez R, Sardón-Prado O, Martin-Gonzalez E, Mederos-Luis E, Poza-Guedes P, Corcuera-Elosegui P, Callero A, Sánchez-Machín I, Korta-Murua J, Pérez-Pérez JA, Villar J, Pino-Yanes M, Lorenzo-Diaz F. Perez-Garcia J, et al. Among authors: espuela ortiz a. J Allergy Clin Immunol. 2023 Mar;151(3):706-715. doi: 10.1016/j.jaci.2022.09.041. Epub 2022 Nov 4. J Allergy Clin Immunol. 2023. PMID: 36343772 Free article.
Association of bronchial steroid inducible methylation quantitative trait loci with asthma and chronic obstructive pulmonary disease treatment response.
Slob EMA, Faiz A, van Nijnatten J, Vijverberg SJH, Longo C, Kutlu M, Chew FT, Sio YY, Herrera-Luis E, Espuela-Ortiz A, Perez-Garcia J, Pino-Yanes M, Burchard EG, Potočnik U, Gorenjak M, Palmer C, Maroteau C, Turner S, Verhamme K, Karimi L, Mukhopadhyay S, Timens W, Hiemstra PS, Pijnenburg MW, Neighbors M, Grimbaldeston MA, Tew GW, Brandsma CA, Berce V, Aliee H, Theis F, Sin DD, Li X, van den Berge M, Maitland-van der Zee AH, Koppelman GH. Slob EMA, et al. Among authors: espuela ortiz a. Clin Transl Allergy. 2022 Aug;12(8):e12173. doi: 10.1002/clt2.12173. Clin Transl Allergy. 2022. PMID: 36036237 Free PMC article. No abstract available.
Multi-ancestry genome-wide association study of asthma exacerbations.
Herrera-Luis E, Ortega VE, Ampleford EJ, Sio YY, Granell R, de Roos E, Terzikhan N, Vergara EE, Hernandez-Pacheco N, Perez-Garcia J, Martin-Gonzalez E, Lorenzo-Diaz F, Hashimoto S, Brinkman P; U-BIOPRED Study Group; Jorgensen AL, Yan Q, Forno E, Vijverberg SJ, Lethem R, Espuela-Ortiz A, Gorenjak M, Eng C, González-Pérez R, Hernández-Pérez JM, Poza-Guedes P, Sardón O, Corcuera P, Hawkins GA, Marsico A, Bahmer T, Rabe KF, Hansen G, Kopp MV, Rios R, Cruz MJ, González-Barcala FJ, Olaguibel JM, Plaza V, Quirce S, Canino G, Cloutier M, Del Pozo V, Rodriguez-Santana JR, Korta-Murua J, Villar J, Potočnik U, Figueiredo C, Kabesch M, Mukhopadhyay S, Pirmohamed M, Hawcutt DB, Melén E, Palmer CN, Turner S, Maitland-van der Zee AH, von Mutius E, Celedón JC, Brusselle G, Chew FT, Bleecker E, Meyers D, Burchard EG, Pino-Yanes M. Herrera-Luis E, et al. Among authors: espuela ortiz a. Pediatr Allergy Immunol. 2022 Jun;33(6):e13802. doi: 10.1111/pai.13802. Pediatr Allergy Immunol. 2022. PMID: 35754128 Free PMC article.
LTA4H rs2660845 association with montelukast response in early and late-onset asthma.
Maroteau C, Espuela-Ortiz A, Herrera-Luis E, Srinivasan S, Carr F, Tavendale R, Wilson K, Hernandez-Pacheco N, Chalmers JD, Turner S, Mukhopadhyay S, Maitland-van der Zee AH, Burchard EG, Pino-Yanes M, Young S, Lassi G, Platt A, Palmer CNA; PiCA Consortium. Maroteau C, et al. Among authors: espuela ortiz a. PLoS One. 2021 Sep 22;16(9):e0257396. doi: 10.1371/journal.pone.0257396. eCollection 2021. PLoS One. 2021. PMID: 34550981 Free PMC article.
The Genomics and Metagenomics of Asthma Severity (GEMAS) Study: Rationale and Design.
Perez-Garcia J, Hernández-Pérez JM, González-Pérez R, Sardón O, Martin-Gonzalez E, Espuela-Ortiz A, Mederos-Luis E, Callero A, Herrera-Luis E, Corcuera P, Sánchez-Machín I, Poza-Guedes P, González García LM, Ramírez-Martín P, Pérez-Negrín L, Izaguirre-Flores H, Barrios-Recio J, Pérez-Rodríguez E, Alcoba-Florez J, Cañas JA, Rodrigo Muñoz JM, Del Pozo V, Korta-Murua J, Pérez Méndez LI, Hernandez-Ferrer M, Villar J, Lorenzo-Diaz F, Pino-Yanes M. Perez-Garcia J, et al. Among authors: espuela ortiz a. J Pers Med. 2020 Sep 11;10(3):123. doi: 10.3390/jpm10030123. J Pers Med. 2020. PMID: 32933076 Free PMC article.
Genome-wide association study reveals a novel locus for asthma with severe exacerbations in diverse populations.
Herrera-Luis E, Espuela-Ortiz A, Lorenzo-Diaz F, Keys KL, Mak ACY, Eng C, Huntsman S, Villar J, Rodriguez-Santana JR, Burchard EG, Pino-Yanes M. Herrera-Luis E, et al. Among authors: espuela ortiz a. Pediatr Allergy Immunol. 2021 Jan;32(1):106-115. doi: 10.1111/pai.13337. Epub 2020 Sep 14. Pediatr Allergy Immunol. 2021. PMID: 32841424 Free PMC article.
12 results