Higgs DR - Search Results

1

Ancient genomic linkage couples metabolism with erythroid development.

Preston AE, Frost JN, Badat M, Teh M, Armitage AE, Norfo R, Wideman SK, Hanifi M, White N, Roy N, Ghesquiere B, Babbs C, Kassouf M, Davies J, Hughes JR, Beagrie R, Higgs DR, Drakesmith H. Preston AE, et al. Among authors: higgs dr. bioRxiv [Preprint]. 2023 Sep 25:2023.09.25.558944. doi: 10.1101/2023.09.25.558944. bioRxiv. 2023. PMID: 37808769 Free PMC article. Preprint.

2

De novo deletion within the telomeric region flanking the human alpha globin locus as a cause of alpha thalassaemia.

Viprakasit V, Kidd AM, Ayyub H, Horsley S, Hughes J, Higgs DR. Viprakasit V, et al. Among authors: higgs dr. Br J Haematol. 2003 Mar;120(5):867-75. doi: 10.1046/j.1365-2141.2003.04197.x. Br J Haematol. 2003. PMID: 12614224 Free article.

3

Comparative analysis of the alpha-like globin clusters in mouse, rat, and human chromosomes indicates a mechanism underlying breaks in conserved synteny.

Tufarelli C, Hardison R, Miller W, Hughes J, Clark K, Ventress N, Frischauf AM, Higgs DR. Tufarelli C, et al. Among authors: higgs dr. Genome Res. 2004 Apr;14(4):623-30. doi: 10.1101/gr.2143604. Genome Res. 2004. PMID: 15060003 Free PMC article.

4

Globin gene activation during haemopoiesis is driven by protein complexes nucleated by GATA-1 and GATA-2.

Anguita E, Hughes J, Heyworth C, Blobel GA, Wood WG, Higgs DR. Anguita E, et al. Among authors: higgs dr. EMBO J. 2004 Jul 21;23(14):2841-52. doi: 10.1038/sj.emboj.7600274. Epub 2004 Jun 24. EMBO J. 2004. PMID: 15215894 Free PMC article.

5

Annotation of cis-regulatory elements by identification, subclassification, and functional assessment of multispecies conserved sequences.

Hughes JR, Cheng JF, Ventress N, Prabhakar S, Clark K, Anguita E, De Gobbi M, de Jong P, Rubin E, Higgs DR. Hughes JR, et al. Among authors: higgs dr. Proc Natl Acad Sci U S A. 2005 Jul 12;102(28):9830-5. doi: 10.1073/pnas.0503401102. Epub 2005 Jul 5. Proc Natl Acad Sci U S A. 2005. PMID: 15998734 Free PMC article.

6

How transcriptional and epigenetic programmes are played out on an individual mammalian gene cluster during lineage commitment and differentiation.

Higgs DR, Vernimmen D, De Gobbi M, Anguita E, Hughes J, Buckle V, Iborra F, Garrick D, Wood WG. Higgs DR, et al. Biochem Soc Symp. 2006;(73):11-22. doi: 10.1042/bss0730011. Biochem Soc Symp. 2006. PMID: 16626283 Free article.

7

Using genomics to study how chromatin influences gene expression.

Higgs DR, Vernimmen D, Hughes J, Gibbons R. Higgs DR, et al. Annu Rev Genomics Hum Genet. 2007;8:299-325. doi: 10.1146/annurev.genom.8.080706.092323. Annu Rev Genomics Hum Genet. 2007. PMID: 17506662 Review.

8

Tissue-specific histone modification and transcription factor binding in alpha globin gene expression.

De Gobbi M, Anguita E, Hughes J, Sloane-Stanley JA, Sharpe JA, Koch CM, Dunham I, Gibbons RJ, Wood WG, Higgs DR. De Gobbi M, et al. Among authors: higgs dr. Blood. 2007 Dec 15;110(13):4503-10. doi: 10.1182/blood-2007-06-097964. Epub 2007 Aug 22. Blood. 2007. PMID: 17715390 Free article.

9

Association between active genes occurs at nuclear speckles and is modulated by chromatin environment.

Brown JM, Green J, das Neves RP, Wallace HA, Smith AJ, Hughes J, Gray N, Taylor S, Wood WG, Higgs DR, Iborra FJ, Buckle VJ. Brown JM, et al. Among authors: higgs dr. J Cell Biol. 2008 Sep 22;182(6):1083-97. doi: 10.1083/jcb.200803174. J Cell Biol. 2008. PMID: 18809724 Free PMC article.

10

The role of X-inactivation in the gender bias of patients with acquired alpha-thalassaemia and myelodysplastic syndrome (ATMDS).

Haas PS, Roy NB, Gibbons RJ, Deville MA, Fisher C, Schwabe M, Bissé E, van Dorsselaer A, Higgs DR, Lübbert M. Haas PS, et al. Among authors: higgs dr. Br J Haematol. 2009 Feb;144(4):538-45. doi: 10.1111/j.1365-2141.2008.07505.x. Br J Haematol. 2009. PMID: 19055664 Free article.

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