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Chromatin remodeller Chd7 is developmentally regulated in the neural crest by tissue-specific transcription factors.
Williams RM, Taylor G, Ling ITC, Candido-Ferreira I, Fountain DM, Mayes S, Ateş-Kalkan PS, Haug JO, Price AJ, McKinney SA, Bozhilovh YK, Tyser RCV, Srinivas S, Hughes JR, Sauka-Spengler T. Williams RM, et al. Among authors: hughes jr. PLoS Biol. 2024 Oct 17;22(10):e3002786. doi: 10.1371/journal.pbio.3002786. eCollection 2024 Oct. PLoS Biol. 2024. PMID: 39418292 Free PMC article.
Focal deletions of a promoter tether activate the IRX3 oncogene in T-cell acute lymphoblastic leukemia.
Rahman S, Bloye G, Farah N, Demeulemeester J, Costa JR, O'Connor D, Pocock R, Rapoz-D'Silva T, Turna A, Wang L, Lee S, Fielding AK, Roels J, Jaksik R, Dawidowska M, Van Vlierberghe P, Hadjur S, Hughes JR, Davies JOJ, Gutierrez A, Kelliher MA, Van Loo P, Dawson MA, Mansour MR. Rahman S, et al. Among authors: hughes jr. Blood. 2024 Nov 28;144(22):2319-2326. doi: 10.1182/blood.2024024300. Blood. 2024. PMID: 39316719 Free article.
Biomarker Detection and Validation for Corneal Involvement in Patients With Acute Infectious Conjunctivitis.
Seitzman GD, Prajna L, Prajna NV, Sansanayudh W, Satitpitakul V, Laovirojjanakul W, Chen C, Zhong L, Ouimette K, Redd T, Deiner MC, Porco TC, McLeod SD, Lietman TM, Hinterwirth A, Doan T; SCORPIO Study Group. Seitzman GD, et al. JAMA Ophthalmol. 2024 Sep 1;142(9):865-871. doi: 10.1001/jamaophthalmol.2024.2891. JAMA Ophthalmol. 2024. PMID: 39145969 Free PMC article.
Single-cell technologies meet Hi-C.
Hughes JR, Davies JOJ. Hughes JR, et al. Nat Genet. 2024 Aug;56(8):1542-1543. doi: 10.1038/s41588-024-01855-y. Nat Genet. 2024. PMID: 39112687 No abstract available.
Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes.
Xiang G, He X, Giardine BM, Isaac KJ, Taylor DJ, McCoy RC, Jansen C, Keller CA, Wixom AQ, Cockburn A, Miller A, Qi Q, He Y, Li Y, Lichtenberg J, Heuston EF, Anderson SM, Luan J, Vermunt MW, Yue F, Sauria MEG, Schatz MC, Taylor J, Göttgens B, Hughes JR, Higgs DR, Weiss MJ, Cheng Y, Blobel GA, Bodine DM, Zhang Y, Li Q, Mahony S, Hardison RC. Xiang G, et al. Among authors: hughes jr. Genome Res. 2024 Aug 20;34(7):1089-1105. doi: 10.1101/gr.277950.123. Genome Res. 2024. PMID: 38951027 Free PMC article.
1,226 results