Rogawski MA - Search Results

1

Efficacy and Safety of XEN1101, a Novel Potassium Channel Opener, in Adults With Focal Epilepsy: A Phase 2b Randomized Clinical Trial.

French JA, Porter RJ, Perucca E, Brodie MJ, Rogawski MA, Pimstone S, Aycardi E, Harden C, Qian J, Rosenblut CL, Kenney C, Beatch GN; X-TOLE Study Group. French JA, et al. Among authors: rogawski ma. JAMA Neurol. 2023 Nov 1;80(11):1145-1154. doi: 10.1001/jamaneurol.2023.3542. JAMA Neurol. 2023. PMID: 37812429 Free PMC article. Clinical Trial.

2

Tolerability and pharmacokinetics of intravenous allopregnanolone with and without midazolam pretreatment in two healthy dogs.

Bruun DA, Ma B, Chen YJ, Wu CY, Aleman M, Zolkowska D, Smiley-Jewell SM, Rogawski MA, Lein PJ. Bruun DA, et al. Among authors: rogawski ma. Epilepsia Open. 2023 Jun;8(2):666-672. doi: 10.1002/epi4.12723. Epub 2023 Apr 26. Epilepsia Open. 2023. PMID: 36919379 Free PMC article.

3

A randomized, open-label, two-treatment crossover study to evaluate the effect of food on the pharmacokinetics of diazepam nasal spray in healthy adults.

Rogawski MA, Slatko G. Rogawski MA, et al. Epilepsia. 2023 Feb;64(2):364-373. doi: 10.1111/epi.17459. Epub 2022 Dec 21. Epilepsia. 2023. PMID: 36413125 Free PMC article. Clinical Trial.

4

Intravenous and Intramuscular Allopregnanolone for Early Treatment of Status Epilepticus: Pharmacokinetics, Pharmacodynamics, and Safety in Dogs.

Vuu I, Patterson EE, Wu CY, Zolkowska D, Leppik IE, Rogawski MA, Worrell GA, Kremen V, Cloyd JC, Coles LD. Vuu I, et al. Among authors: rogawski ma. J Pharmacol Exp Ther. 2022 Feb;380(2):104-113. doi: 10.1124/jpet.121.000736. Epub 2021 Dec 3. J Pharmacol Exp Ther. 2022. PMID: 34862270 Free PMC article.

5

Strain differences in the extent of brain injury in mice after tetramethylenedisulfotetramine-induced status epilepticus.

Calsbeek JJ, González EA, Boosalis CA, Zolkowska D, Bruun DA, Rowland DJ, Saito NH, Harvey DJ, Chaudhari AJ, Rogawski MA, Garbow JR, Lein PJ. Calsbeek JJ, et al. Among authors: rogawski ma. Neurotoxicology. 2021 Dec;87:43-50. doi: 10.1016/j.neuro.2021.08.011. Epub 2021 Aug 31. Neurotoxicology. 2021. PMID: 34478772 Free PMC article.

6

Cortical excitability threshold can be increased by the AMPA blocker Perampanel in amyotrophic lateral sclerosis.

Oskarsson B, Mauricio EA, Shah JS, Li Z, Rogawski MA. Oskarsson B, et al. Among authors: rogawski ma. Muscle Nerve. 2021 Aug;64(2):215-219. doi: 10.1002/mus.27328. Epub 2021 May 27. Muscle Nerve. 2021. PMID: 34008857 Clinical Trial.

7

Perampanel, a potent AMPA receptor antagonist, protects against tetramethylenedisulfotetramine-induced seizures and lethality in mice: comparison with diazepam.

Zolkowska D, Dhir A, Rogawski MA. Zolkowska D, et al. Among authors: rogawski ma. Arch Toxicol. 2021 Jul;95(7):2459-2468. doi: 10.1007/s00204-021-03053-9. Epub 2021 Apr 29. Arch Toxicol. 2021. PMID: 33914090 Free PMC article.

8

Intranasal Allopregnanolone Confers Rapid Seizure Protection: Evidence for Direct Nose-to-Brain Delivery.

Zolkowska D, Wu CY, Rogawski MA. Zolkowska D, et al. Among authors: rogawski ma. Neurotherapeutics. 2021 Jan;18(1):544-555. doi: 10.1007/s13311-020-00985-5. Epub 2021 Jan 6. Neurotherapeutics. 2021. PMID: 33405197 Free PMC article.

9

Safety, tolerability, and pharmacokinetics of allopregnanolone as a regenerative therapeutic for Alzheimer's disease: A single and multiple ascending dose phase 1b/2a clinical trial.

Hernandez GD, Solinsky CM, Mack WJ, Kono N, Rodgers KE, Wu CY, Mollo AR, Lopez CM, Pawluczyk S, Bauer G, Matthews D, Shi Y, Law M, Rogawski MA, Schneider LS, Brinton RD. Hernandez GD, et al. Among authors: rogawski ma. Alzheimers Dement (N Y). 2020 Dec 16;6(1):e12107. doi: 10.1002/trc2.12107. eCollection 2020. Alzheimers Dement (N Y). 2020. PMID: 33344752 Free PMC article.

10

Allopregnanolone and perampanel as adjuncts to midazolam for treating diisopropylfluorophosphate-induced status epilepticus in rats.

Dhir A, Bruun DA, Guignet M, Tsai YH, González E, Calsbeek J, Vu J, Saito N, Tancredi DJ, Harvey DJ, Lein PJ, Rogawski MA. Dhir A, et al. Among authors: rogawski ma. Ann N Y Acad Sci. 2020 Nov;1480(1):183-206. doi: 10.1111/nyas.14479. Epub 2020 Sep 11. Ann N Y Acad Sci. 2020. PMID: 32915470 Free PMC article.

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