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Page 1
Expressed Protein Ligation in Flow.
Kambanis L, Ayoub A, Bedding MJ, Egelund PHG, Maxwell JWC, Franck C, Lambrechts L, Hawkins PME, Chisholm TS, Mackay JP, Sierecki E, Gambin Y, Kulkarni SS, Payne RJ. Kambanis L, et al. Among authors: bedding mj. J Am Chem Soc. 2024 Aug 7;146(31):22027-22035. doi: 10.1021/jacs.4c07462. Epub 2024 Jul 25. J Am Chem Soc. 2024. PMID: 39052634
Exploiting Hydrophobic Amino Acid Scanning to Develop Cyclic Peptide Inhibitors of the SARS-CoV-2 Main Protease with Antiviral Activity.
Harrison K, Carlos PW, Ullrich S, Aggarwal A, Johansen-Leete J, Sasi VM, Barter I, Maxwell JWC, Bedding MJ, Larance M, Turville S, Norman A, Jackson CJ, Nitsche C, Payne RJ. Harrison K, et al. Among authors: bedding mj. Chemistry. 2024 Aug 6;30(44):e202401606. doi: 10.1002/chem.202401606. Epub 2024 Jul 17. Chemistry. 2024. PMID: 38801240
Electrochemical Modification of Polypeptides at Selenocysteine.
Mackay AS, Maxwell JWC, Bedding MJ, Kulkarni SS, Byrne SA, Kambanis L, Popescu MV, Paton RS, Malins LR, Ashhurst AS, Corcilius L, Payne RJ. Mackay AS, et al. Among authors: bedding mj. Angew Chem Int Ed Engl. 2023 Dec 11;62(50):e202313037. doi: 10.1002/anie.202313037. Epub 2023 Nov 9. Angew Chem Int Ed Engl. 2023. PMID: 37818778
Antiviral cyclic peptides targeting the main protease of SARS-CoV-2.
Johansen-Leete J, Ullrich S, Fry SE, Frkic R, Bedding MJ, Aggarwal A, Ashhurst AS, Ekanayake KB, Mahawaththa MC, Sasi VM, Luedtke S, Ford DJ, O'Donoghue AJ, Passioura T, Larance M, Otting G, Turville S, Jackson CJ, Nitsche C, Payne RJ. Johansen-Leete J, et al. Among authors: bedding mj. Chem Sci. 2022 Feb 28;13(13):3826-3836. doi: 10.1039/d1sc06750h. eCollection 2022 Mar 30. Chem Sci. 2022. PMID: 35432913 Free PMC article.
Potent Anti-SARS-CoV-2 Activity by the Natural Product Gallinamide A and Analogues via Inhibition of Cathepsin L.
Ashhurst AS, Tang AH, Fajtová P, Yoon MC, Aggarwal A, Bedding MJ, Stoye A, Beretta L, Pwee D, Drelich A, Skinner D, Li L, Meek TD, McKerrow JH, Hook V, Tseng CT, Larance M, Turville S, Gerwick WH, O'Donoghue AJ, Payne RJ. Ashhurst AS, et al. Among authors: bedding mj. J Med Chem. 2022 Feb 24;65(4):2956-2970. doi: 10.1021/acs.jmedchem.1c01494. Epub 2021 Nov 3. J Med Chem. 2022. PMID: 34730959 Free PMC article.