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Page 1
Protein citrullination and NET formation do not contribute to the pathology of A20/TNFAIP3 mutant mice.
Van Damme KFA, Hertens P, Martens A, Gilis E, Priem D, Bruggeman I, Fossoul A, Declercq J, Aegerter H, Wullaert A, Hochepied T, Hoste E, Vande Walle L, Lamkanfi M, Savvides SN, Elewaut D, Lambrecht BN, van Loo G. Van Damme KFA, et al. Among authors: martens a. Sci Rep. 2023 Oct 21;13(1):17992. doi: 10.1038/s41598-023-45324-8. Sci Rep. 2023. PMID: 37865713 Free PMC article.
A20 phosphorylation controls A20 function.
Martens A, van Loo G. Martens A, et al. Nat Immunol. 2019 Oct;20(10):1261-1262. doi: 10.1038/s41590-019-0481-3. Nat Immunol. 2019. PMID: 31534239 No abstract available.
Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities.
Martens A, Priem D, Hoste E, Vetters J, Rennen S, Catrysse L, Voet S, Deelen L, Sze M, Vikkula H, Slowicka K, Hochepied T, Iliaki K, Wullaert A, Janssens S, Lamkanfi M, Beyaert R, Armaka M, Bertrand MJM, van Loo G. Martens A, et al. Nat Immunol. 2020 Apr;21(4):381-387. doi: 10.1038/s41590-020-0621-9. Epub 2020 Mar 16. Nat Immunol. 2020. PMID: 32205881
A20 deficiency in myeloid cells protects mice from diet-induced obesity and insulin resistance due to increased fatty acid metabolism.
Catrysse L, Maes B, Mehrotra P, Martens A, Hoste E, Martens L, Maueröder C, Remmerie A, Bujko A, Slowicka K, Sze M, Vikkula H, Ghesquière B, Scott CL, Saeys Y, van de Sluis B, Ravichandran K, Janssens S, van Loo G. Catrysse L, et al. Among authors: martens l, martens a. Cell Rep. 2021 Sep 21;36(12):109748. doi: 10.1016/j.celrep.2021.109748. Cell Rep. 2021. PMID: 34551300 Free article.
A20 controls RANK-dependent osteoclast formation and bone physiology.
Martens A, Hertens P, Priem D, Rinotas V, Meletakos T, Gennadi M, Van Hove L, Louagie E, Coudenys J, De Muynck A, Gaublomme D, Sze M, van Hengel J, Catrysse L, Hoste E, Zajac JD, Davey RA, Van Hoorebeke L, Hochepied T, Bertrand MJM, Armaka M, Elewaut D, van Loo G. Martens A, et al. EMBO Rep. 2022 Dec 6;23(12):e55233. doi: 10.15252/embr.202255233. Epub 2022 Oct 4. EMBO Rep. 2022. PMID: 36194667 Free PMC article.
Physical and functional interaction between A20 and ATG16L1-WD40 domain in the control of intestinal homeostasis.
Slowicka K, Serramito-Gómez I, Boada-Romero E, Martens A, Sze M, Petta I, Vikkula HK, De Rycke R, Parthoens E, Lippens S, Savvides SN, Wullaert A, Vereecke L, Pimentel-Muiños FX, van Loo G. Slowicka K, et al. Among authors: martens a. Nat Commun. 2019 Apr 23;10(1):1834. doi: 10.1038/s41467-019-09667-z. Nat Commun. 2019. PMID: 31015422 Free PMC article.
OTULIN Prevents Liver Inflammation and Hepatocellular Carcinoma by Inhibiting FADD- and RIPK1 Kinase-Mediated Hepatocyte Apoptosis.
Verboom L, Martens A, Priem D, Hoste E, Sze M, Vikkula H, Van Hove L, Voet S, Roels J, Maelfait J, Bongiovanni L, de Bruin A, Scott CL, Saeys Y, Pasparakis M, Bertrand MJM, van Loo G. Verboom L, et al. Among authors: martens a. Cell Rep. 2020 Feb 18;30(7):2237-2247.e6. doi: 10.1016/j.celrep.2020.01.028. Cell Rep. 2020. PMID: 32075762 Free article.
Identification of Immune-Responsive Gene 1 (IRG1) as a Target of A20.
Van Quickelberghe E, Martens A, Goeminne LJE, Clement L, van Loo G, Gevaert K. Van Quickelberghe E, et al. Among authors: martens a. J Proteome Res. 2018 Jun 1;17(6):2182-2191. doi: 10.1021/acs.jproteome.8b00139. Epub 2018 May 11. J Proteome Res. 2018. PMID: 29733654
A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation.
Voet S, Mc Guire C, Hagemeyer N, Martens A, Schroeder A, Wieghofer P, Daems C, Staszewski O, Vande Walle L, Jordao MJC, Sze M, Vikkula HK, Demeestere D, Van Imschoot G, Scott CL, Hoste E, Gonçalves A, Guilliams M, Lippens S, Libert C, Vandenbroucke RE, Kim KW, Jung S, Callaerts-Vegh Z, Callaerts P, de Wit J, Lamkanfi M, Prinz M, van Loo G. Voet S, et al. Among authors: martens a. Nat Commun. 2018 May 23;9(1):2036. doi: 10.1038/s41467-018-04376-5. Nat Commun. 2018. PMID: 29789522 Free PMC article.
730 results